Serotonin reuptake inhibition: an update on current research strategies.
about
Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease.Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT(1A) receptor.Development of potent dopamine-norepinephrine uptake inhibitors (DNRIs) based on a (2S,4R,5R)-2-benzhydryl-5-((4-methoxybenzyl)amino)tetrahydro-2H-pyran-4-ol molecular template.The novel trisubstituted pyran derivative D-142 has triple monoamine reuptake inhibitory activity and exerts potent antidepressant-like activity in rodents.Trends in the development of new antidepressants. Is there a light at the end of the tunnel?High-throughput electronic biology: mining information for drug discovery.Structural exploration of (3S,6S)-6-benzhydryl-N-benzyltetrahydro-2H-pyran-3-amine analogues: identification of potent triple monoamine reuptake inhibitors as potential antidepressants3-Aryl-3-arylmethoxyazetidines. A new class of high affinity ligands for monoamine transporters.Triple reuptake inhibitors as potential next-generation antidepressants: a new hope?Synthesis and monoamine transporter affinity of 3alpha-arylmethoxy-3beta-arylnortropanes.Flexible and biomimetic analogs of triple uptake inhibitor 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: Synthesis, biological characterization, and development of a pharmacophore model.Differential, but not opponent, effects of L -DOPA and citalopram on action learning with reward and punishment.Neurochemical modulation of response inhibition and probabilistic learning in humans.GABA transporter-1 (GAT1)-deficient mice: differential tonic activation of GABAA versus GABAB receptors in the hippocampus.3-[(Aryl)(4-fluorobenzyloxy)methyl]piperidine derivatives: high-affinity ligands for the serotonin transporter.Revealing vilazodone's binding mechanism underlying its partial agonism to the 5-HT1A receptor in the treatment of major depressive disorder.Synthesis and evaluation of novel 2,3-dihydrobenzo[b][1,4]dioxin- and indolealkylamine derivatives as potential antidepressants.
P2860
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P2860
Serotonin reuptake inhibition: an update on current research strategies.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Serotonin reuptake inhibition: an update on current research strategies.
@ast
Serotonin reuptake inhibition: an update on current research strategies.
@en
Serotonin reuptake inhibition: an update on current research strategies.
@nl
type
label
Serotonin reuptake inhibition: an update on current research strategies.
@ast
Serotonin reuptake inhibition: an update on current research strategies.
@en
Serotonin reuptake inhibition: an update on current research strategies.
@nl
prefLabel
Serotonin reuptake inhibition: an update on current research strategies.
@ast
Serotonin reuptake inhibition: an update on current research strategies.
@en
Serotonin reuptake inhibition: an update on current research strategies.
@nl
P356
P1476
Serotonin reuptake inhibition: an update on current research strategies.
@en
P2093
P304
P356
10.2174/0929867024606795
P577
2002-04-01T00:00:00Z