Revisiting thymic positive selection and the mature T cell repertoire for antigen.
about
Lower Affinity T Cells are Critical Components and Active Participants of the Immune ResponseIndoctrinating T cells to attack pathogens through homeschoolingEstablishment and Maintenance of the Human Naïve CD4+ T-Cell CompartmentTCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicitySelf-recognition drives the preferential accumulation of promiscuous CD4(+) T-cells in aged mice.T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production.Brief Report: Role of Thymic Reconstitution in the Outcome of AIDS-Related PMLHydrophobic CDR3 residues promote the development of self-reactive T cells.DNA demethylating agent decitabine broadens the peripheral T cell receptor repertoire.MHC class I-associated peptides derive from selective regions of the human genome.Human TCR-MHC coevolution after divergence from mice includes increased nontemplate-encoded CDR3 diversity.Cutting Edge: CD3 ITAM Diversity Is Required for Optimal TCR Signaling and Thymocyte Development.Development of T-cell tolerance utilizes both cell-autonomous and cooperative presentation of self-antigen.Self-reactivity as the necessary cost of maintaining a diverse memory T-cell repertoire.Ectopic Aire Expression in the Thymic Cortex Reveals Inherent Properties of Aire as a Tolerogenic Factor within the Medulla.Crossreactive αβ T Cell Receptors Are the Predominant Targets of Thymocyte Negative Selection.NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoing positive selection.A "hotspot" for autoimmune T cells in type 1 diabetes.The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor.Regulatory T cells constrain the TCR repertoire of antigen-stimulated conventional CD4 T cells.Preparation and Applications of Organotypic Thymic Slice Cultures.A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice.
P2860
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P2860
Revisiting thymic positive selection and the mature T cell repertoire for antigen.
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Revisiting thymic positive selection and the mature T cell repertoire for antigen.
@ast
Revisiting thymic positive selection and the mature T cell repertoire for antigen.
@en
Revisiting thymic positive selection and the mature T cell repertoire for antigen.
@nl
type
label
Revisiting thymic positive selection and the mature T cell repertoire for antigen.
@ast
Revisiting thymic positive selection and the mature T cell repertoire for antigen.
@en
Revisiting thymic positive selection and the mature T cell repertoire for antigen.
@nl
prefLabel
Revisiting thymic positive selection and the mature T cell repertoire for antigen.
@ast
Revisiting thymic positive selection and the mature T cell repertoire for antigen.
@en
Revisiting thymic positive selection and the mature T cell repertoire for antigen.
@nl
P2093
P2860
P1433
P1476
Revisiting thymic positive selection and the mature T cell repertoire for antigen.
@en
P2093
João P Monteiro
Judith N Mandl
Nienke Vrisekoop
Ronald N Germain
P2860
P304
P356
10.1016/J.IMMUNI.2014.07.007
P407
P577
2014-08-01T00:00:00Z