Increased Src activity disrupts cadherin/catenin-mediated homotypic adhesion in human colon cancer and transformed rodent cells.
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Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.Elevated Src family kinase activity stabilizes E-cadherin-based junctions and collective movement of head and neck squamous cell carcinomas.Primary cell lines: false representation or model system? a comparison of four human colorectal tumors and their coordinately established cell linesQuantification of beta-catenin signaling components in colon cancer cell lines, tissue sections, and microdissected tumor cells using reaction monitoring mass spectrometry.Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells.Major role of epidermal growth factor receptor and Src kinases in promoting oxidative stress-dependent loss of adhesion and apoptosis in epithelial cells.Focal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasisProstate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network.Transendothelial migration of melanoma cells involves N-cadherin-mediated adhesion and activation of the beta-catenin signaling pathwayTwo N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis.SRC: a century of science brought to the clinic.Expression, purification, and bioactivity of GST-fused v-Src from a bacterial expression system.A PKA-Csk-pp60Src signaling pathway regulates the switch between endothelial cell invasion and cell-cell adhesion during vascular sprouting.Increases in c-Src expression level and activity do not promote the growth of human colorectal carcinoma cells in vitro and in vivo.Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase.Phase 2 study of bosutinib, a Src inhibitor, in adults with recurrent glioblastoma.Simultaneous expression of caveolin-1 and E-cadherin in ovarian carcinoma cells stabilizes adherens junctions through inhibition of src-related kinasesInterface between breast cancer cells and the tumor microenvironment using platelet-rich plasma to promote tumor angiogenesis - influence of platelets and fibrin bundles on the behavior of breast tumor cells.Src and ADAM-17-mediated shedding of transforming growth factor-alpha is a mechanism of acute resistance to TRAILRegulation of homotypic cell-cell adhesion by branched N-glycosylation of N-cadherin extracellular EC2 and EC3 domains.A regulatory polymorphism at position -309 in PTPRCAP is associated with susceptibility to diffuse-type gastric cancer and gene expression.Oncogenic signaling by tyrosine kinases of the SRC family in advanced colorectal cancer.Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src.Novel mechanistic insights into ectodomain shedding of EGFR Ligands Amphiregulin and TGF-α: impact on gastrointestinal cancers driven by secondary bile acids.A central role for cadherin signaling in cancer.Pervanadate stabilizes desmosomes.Focal adhesion kinase regulates cell-cell contact formation in epithelial cells via modulation of Rho.Caveolin-1-mediated expression and secretion of kallikrein 6 in colon cancer cells.Raf-1 activation in gastrointestinal carcinoid cells decreases tumor cell adhesion.Involvement of Src family kinases in N-cadherin phosphorylation and beta-catenin dissociation during transendothelial migration of melanoma cells.Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitionsPreclinical anticancer activity of the potent, oral Src inhibitor AZD0530Src transformation of colonic epithelial cells: enhanced anchorage-independent growth in an Apc(+/min) background.Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling.
P2860
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P2860
Increased Src activity disrupts cadherin/catenin-mediated homotypic adhesion in human colon cancer and transformed rodent cells.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Increased Src activity disrupt ...... and transformed rodent cells.
@ast
Increased Src activity disrupt ...... and transformed rodent cells.
@en
Increased Src activity disrupt ...... and transformed rodent cells.
@nl
type
label
Increased Src activity disrupt ...... and transformed rodent cells.
@ast
Increased Src activity disrupt ...... and transformed rodent cells.
@en
Increased Src activity disrupt ...... and transformed rodent cells.
@nl
prefLabel
Increased Src activity disrupt ...... and transformed rodent cells.
@ast
Increased Src activity disrupt ...... and transformed rodent cells.
@en
Increased Src activity disrupt ...... and transformed rodent cells.
@nl
P1433
P1476
Increased Src activity disrupt ...... r and transformed rodent cells
@en
P2093
Rosalyn B Irby
Timothy J Yeatman
P304
P407
P577
2002-05-01T00:00:00Z