An essential role for DNA methyltransferase DNMT3B in cancer cell survival. - Wikidata - awgldk - TriplyDB

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

http://www.wikidata.org/entity/Q34128797

about

Inactive DNMT3B splice variants modulate de novo DNA methylation DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2 Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation Identification of microRNAs with regulatory potential using a matched microRNA-mRNA time-course data.HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors.DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer Depletion of DNMT3A suppressed cell proliferation and restored PTEN in hepatocellular carcinoma cell.Ornithine decarboxylase antizyme induces hypomethylation of genome DNA and histone H3 lysine 9 dimethylation (H3K9me2) in human oral cancer cell line.An epigenetic perspective on the free radical theory of development Epigenetic drugs against cancer: an evolving landscape.Suppression of intestinal neoplasia by deletion of Dnmt3b.The role of genetics in the establishment and maintenance of the epigenome.Down-regulation of DNMT3b in PC3 cells effects locus-specific DNA methylation, and represses cellular growth and migration.Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b.Methylator phenotype of malignant germ cell tumours in children identifies strong candidates for chemotherapy resistance.DNA methyltransferase 3b silencing affects locus-specific DNA methylation and inhibits proliferation, migration and invasion in human hepatocellular carcinoma SMMC-7721 and BEL-7402 cells.Connections between epigenetic gene silencing and human disease.A comprehensive analysis of radiosensitization targets; functional inhibition of DNA methyltransferase 3B radiosensitizes by disrupting DNA damage regulation.DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity Tumor suppressor gene inactivation during cadmium-induced malignant transformation of human prostate cells correlates with overexpression of de novo DNA methyltransferase.Epigenetic changes in virus-associated human cancers.Concise review: The evolution of human pluripotent stem cell culture: from feeder cells to synthetic coatings Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer.Promoter polymorphisms of DNMT3B and the risk of colorectal cancer in Chinese: a case-control study.Identification of DNMT1 selective antagonists using a novel scintillation proximity assay.DNA methylation in development and human disease DNMT3B 579 G>T promoter polymorphism and risk of esophagus carcinoma in Chinese DNA methyltransferases and TETs in the regulation of differentiation and invasiveness of extra-villous trophoblasts.Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression.A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding.Metabolic defects provide a spark for the epigenetic switch in cancer.Inhibition of de novo Methyltransferase 3B is a Potential Therapy for Hepatocellular Carcinoma.Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities.Epigenetics and blood disorders.Transcriptional regulation of the human DNA methyltransferase 3A and 3B genes by Sp3 and Sp1 zinc finger proteins.DNMT3b Modulates Melanoma Growth by Controlling Levels of mTORC2 Component RICTOR.Aza-deoxycytidine induces apoptosis or differentiation via DNMT3B and targets embryonal carcinoma cells but not their differentiated derivatives.Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibition of Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: Therapeutic Implications.Methy-sens Comet assay and DNMTs transcriptional analysis as a combined approach in epigenotoxicology.Oncogenic nature of a novel mutant AATF and its interactome existing within human cancer cells.

P2860

Q28534738-6FA30D2E-C2B5-4528-AD53-166136FB1CEC Q28584099-1F6A7D96-FD3D-48F5-8BF3-B8D5E0A09C9F Q28730186-9A36A12D-C26E-4172-8432-FD6646A6C2CA Q33419254-98C35DC4-7F3C-40F5-8D67-F0D1D874721A Q33818402-9179E87D-5936-44E3-92FF-747647F46A8D Q33837632-F18F3733-55CA-4E5B-93A8-44344701A338 Q33847115-45D868B2-DA03-4DF4-9F0F-C5FF0E89BA09 Q34103537-D6DFA64C-B9BE-43A2-93C0-879977C4686E Q34309185-5900A316-072C-4C46-A4A2-B26A67132ECF Q34431964-E43E7347-BF56-49E4-A490-D5A591C4E55A Q34563186-8D3C15DB-3194-41C9-A685-11A670F256BD Q34649133-B593D594-737E-484D-B369-F70C5A47D39B Q34829786-E0FB1BC7-043B-4C03-8F40-1F515539CF47 Q35169651-BC221E7E-1B25-4A98-BC1D-8918D1B58A07 Q35208036-57D0FE78-80DF-4A80-B322-FEEDBF352F01 Q35758190-AAA49162-A947-4974-BA34-C5260B0C33FD Q35843804-6B6C9121-55EF-402B-81AF-DF7B7E6A7C83 Q35868661-F47C8B95-AB13-46FB-9825-4B0B18B89AD0 Q36032155-04C71495-7D14-4E8A-B3FB-AAF818AEFF92 Q36065002-F178FB22-2CC0-455C-96B0-0FCDE1551F60 Q36109306-F3A38B66-9F15-4822-B0EE-5A1805C72762 Q36509204-3C12C1E0-2678-4625-8D50-F884795A36EA Q36667464-2493E0E7-0376-427C-B39A-D01A3D8D53BC Q36836582-0E195B71-80CA-4181-87B7-0005EB8442B0 Q37000576-232DD11D-454E-4C08-A200-88F0C8A7B318 Q37110130-E609366B-75CD-4027-9BA0-BA8103C9919F Q37245503-EF53D3D0-B4AE-4D8F-A041-1841D9FE2F54 Q37361953-88C3254B-E858-49B3-A35A-2FDA9654E771 Q37419612-B9D54872-51F5-4914-81C9-EC3704D6E1C6 Q37440613-D1627802-C13E-49A2-89DD-3A357EBB212D Q37442063-4623B828-0861-42BD-94BD-B02418213AA5 Q37498968-65C0F8A9-2A0F-4B8C-B916-934A6C345940 Q37737945-EFEC369D-10DB-4C08-AF73-3E8AC77DF026 Q38019955-3F11FFF1-AE5A-418A-9BDE-A9ED9B257C41 Q38336777-BAAC5DA9-61AB-424E-8388-CEF424CB87AE Q38790387-5877CDD2-5088-43DD-9062-BA059EBF6CD7 Q38838783-25B8ECA6-AC88-49BB-9CC3-905AC657A84E Q38876540-A746CF3F-1223-437D-8871-74A6587733C6 Q38927646-6792C71A-0692-4813-B5FC-D5203325C035 Q38955553-635E862B-5972-46E2-95F4-2303C465FD85

P2860

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

http://www.wikidata.org/entity/Q34128797

description

2002 nî lūn-bûn

@nan

2002 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

@ast

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

@en

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

@nl

type

label

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

@ast

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

@en

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

@nl

prefLabel

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

@ast

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

@en

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

@nl

P1433

Q34128797-009472C7-7BAA-4C86-9D2A-7D9276697F75

P1476

Q34128797-AE1A30D6-3F5F-47D8-9E6E-82E795AC8A1B

P2093

Q34128797-16EF8554-23E7-4AC2-87C1-F96A26D2CBAB

Q34128797-4C2C41E5-6A4D-437B-BE76-5AE82EDE24C6

Q34128797-8BB57D9D-03CA-4267-9BCE-ED6D47A218C4

Q34128797-C10F26E5-E1AD-45FA-82A9-11D75E9BBE45

Q34128797-D4E851C2-D107-4FEA-966A-03FABCF60530

Q34128797-F5A70D44-EAA4-41C9-A8FE-717062C02D0F

P2860

Q34128797-0FCDC5BF-090A-472A-9C63-8A8A83A8B9F2

Q34128797-10FBA7DD-3D58-4689-99FC-25AC5CDF1E26

Q34128797-1B5F0936-1B94-463B-A311-4A9D161F3C5B

Q34128797-294E00F1-0407-4EFA-ACAF-03C84A566E48

Q34128797-3B79F999-DEAE-43D8-8D10-2E32622D46B7

Q34128797-4F44BE98-090E-42E8-B2D5-5D2A697E31B1

Q34128797-5149FCCF-BD80-4D46-9973-37633C2C6EB5

Q34128797-52A661DA-AFB8-4CA1-9F25-91A09C71C03F

Q34128797-5431A333-CD47-4336-9EFE-D8D49E7CB79C

Q34128797-549A9D02-F596-4ADC-B6B6-B52D8DBDC941

P304

Q34128797-F2FAB1F4-5B32-43A2-9C1E-D92BCB4F1AA2

P31

Q34128797-D4D6F2BC-EB7D-4B63-85A6-DF0F88D397A9

P356

Q34128797-C00E1758-DC46-41A6-95AB-2C6BD48E9156

P407

Q34128797-FB0C4727-4F8E-46F1-881F-5DE3720AAA7D

P433

Q34128797-9B1EBB9B-EAE7-4E1B-9338-54C401CAA8A9

P478

Q34128797-356FA29C-0730-40BB-8431-BF2AE91EFC61

P577

Q34128797-534E9EAA-185D-4E2C-B35B-599020C12121

P698

Q34128797-EF2F7D85-AEE6-426B-8D04-32E05992D6AD

P356

P1433

Journal of Biological Chemistry

P1476

An essential role for DNA methyltransferase DNMT3B in cancer cell survival.

@en

P2093

A Robert MacLeod

http://www.w3.org/2001/XMLSchema#string

Hannah Nguyen

http://www.w3.org/2001/XMLSchema#string

Ian C Chute

http://www.w3.org/2001/XMLSchema#string

Marie-France Robert

http://www.w3.org/2001/XMLSchema#string

Normand Beaulieu

http://www.w3.org/2001/XMLSchema#string

Steves Morin

http://www.w3.org/2001/XMLSchema#string

P2860

Role of DNA 5-methylcytosine transferase in cell transformation by fos

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

Cloning, expression and chromosome locations of the human DNMT3 gene family

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression

Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

P304

28176-28181

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M204734200

http://www.w3.org/2001/XMLSchema#string

P407

P433

31

http://www.w3.org/2001/XMLSchema#string

P478

277

http://www.w3.org/2001/XMLSchema#string

P577

2002-05-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

12015329

http://www.w3.org/2001/XMLSchema#string