A critical evaluation of in vitro cell culture models for high-throughput drug screening and toxicity.
about
Animal-Free Chemical Safety AssessmentModeling Barrier Tissues In Vitro: Methods, Achievements, and ChallengesHuman corneal cell culture models for drug toxicity studiesDevelopment of a convenient in vivo hepatotoxin assay using a transgenic zebrafish line with liver-specific DsRed expressionHydrogel Based 3-Dimensional (3D) System for Toxicity and High-Throughput (HTP) Analysis for Cultured Murine Ovarian FolliclesNew surface radiolabeling schemes of super paramagnetic iron oxide nanoparticles (SPIONs) for biodistribution studiesBiology-inspired microphysiological system approaches to solve the prediction dilemma of substance testingBreath biomarkers in toxicology.Standing surface acoustic wave based cell coculture.Data-driven approaches used for compound library design, hit triage and bioactivity modeling in high-throughput screening.Three-dimensional osteogenic and chondrogenic systems to model osteochondral physiology and degenerative joint diseasesMicroarray platform affords improved product analysis in mammalian cell growth studies.Toxicologic pathology in the 21st century.Bioconversion of α-linolenic acid into n-3 long-chain polyunsaturated fatty acid in hepatocytes and ad hoc cell culture optimisation.The relevance and potential roles of microphysiological systems in biology and medicineQuantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.Biomimetic 3D Tissue Models for Advanced High-Throughput Drug Screening.Toxicity Minimized Cryoprotectant Addition and Removal Procedures for Adherent Endothelial CellsFunctional and cytometric examination of different human lung epithelial cell types as drug transport barriersThree-dimensional (3D) tumor spheroid invasion assay.Effects of a discoloration-resistant calcium aluminosilicate cement on the viability and proliferation of undifferentiated human dental pulp stem cells.Quantification of Low-Level Drug Effects Using Real-Time, in vitro Measurement of Oxygen Consumption Rate.Modeling Fetal Alcohol Spectrum Disorder: Validating an Ex Vivo Primary Hippocampal Cell Culture System.Biology of the cardiac myocyte in heart disease.Clarifying intact 3D tissues on a microfluidic chip for high-throughput structural analysis.Designing regenerative biomaterial therapies for the clinic.Three-dimensionally engineered biomimetic tissue models for in vitro drug evaluation: delivery, efficacy and toxicity.Oncogene and non-oncogene addiction in inflammation-associated cancers.Assessing nanoparticle toxicity in cell-based assays: influence of cell culture parameters and optimized models for bridging the in vitro-in vivo gap.3D in vitro tissue models and their potential for drug screening.An evaluation of the latest in vitro tools for drug metabolism studies.Linking physiology to toxicity using DILIsym®, a mechanistic mathematical model of drug-induced liver injury.Cardiomyocyte culture - an update on the in vitro cardiovascular model and future challenges.Drug safety testing paradigm, current progress and future challenges: an overview.Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment.Regulatory toxicology in the twenty-first century: challenges, perspectives and possible solutions.Omics for aquatic ecotoxicology: control of extraneous variability to enhance the analysis of environmental effects.New developments concerning the proximal tubule in diabetic nephropathy: in vitro models and mechanisms.Employing proteomics to unravel the molecular effects of antipsychotics and their role in schizophrenia.Hydrogel Environment Supports Cell Culture Expansion of a Grade IV Astrocytoma.
P2860
Q26738977-2AAC92F9-72B7-415A-9520-C196436E9324Q26748486-258714D9-6399-4845-B559-2E6EDE1CF0DFQ28080232-0893B4C3-0B1D-40E9-AEFC-9BB47E871957Q28540884-258282D3-D8EF-4806-BA61-3BC321756434Q28550164-F90FDAA0-6AAA-4633-90CF-C562B27BEC3EQ28834078-6878C6BD-9461-4E30-A195-F972E4DF1B60Q30358385-7EA1EE34-A48F-4F00-9330-05B6FE773D32Q30392488-E0C1F958-DBC1-4687-A066-34AC21E2A304Q30402674-86AE724A-5010-4354-A2F8-5E7B535120A3Q31139520-0D0A66D7-8C66-4B3B-8BBD-923EE965DD45Q33628872-021233DF-172A-4BC4-8556-ADE512541B93Q34031179-36032236-393D-4823-961A-7DB7CC656457Q34473377-293AC44F-81BD-4CA6-8AD8-D202663F8531Q34989183-C8477B57-9FE4-40AE-BCC4-65A8D2217986Q35090569-E4CFF6D8-C604-4476-AE48-138A58BF4EA2Q35592860-CB9DA643-E514-4B98-AF3B-787BE515B277Q35694549-C4D275A2-8F94-4F3C-B9F5-9EE90BD9887FQ35852102-FF3AF9F0-39F5-4444-80D7-60E090E2AFE3Q35889102-0FD1267D-E1F3-4706-A792-CE6194D64FA9Q35972563-386599BD-935D-48D5-ACAC-94D4463413BEQ36329470-83C57FA5-42E0-46D3-A8EA-9A83A08802C4Q36794245-01157F44-9883-464B-8BB5-B59FC0D0F16FQ36957804-46C19447-A016-4945-A933-86791F3D71D9Q37095254-8E84A51D-81D8-4E37-A59A-C00171CC13E4Q37549815-B3660197-7F1C-4C9D-AAE4-BC6628A26534Q38059838-206D0A10-7991-4189-A093-CD5A2850F1E8Q38071670-7416C792-0767-4D52-8A14-420061DF4A81Q38096415-E54D2F04-D15D-4694-9857-FD3840BD7096Q38123394-FE7671D7-6E88-401D-A9D3-C14193EC5862Q38154340-3F8BFE89-F4D7-412D-A341-22A6523D7041Q38160881-572F409A-77AE-44EE-8797-3AA8F1530CAEQ38161471-C2C9AD6F-0D48-4E7E-B8A5-7EBFDD04E0A9Q38167330-41DBD157-4086-4829-9E6B-7C08A8B3CF51Q38207946-B16D264B-C6C9-4DDA-8996-79E8869BE323Q38218018-6151C4CB-0E08-4EF7-B743-B20B2BBB5F81Q38395314-A3C55A14-D380-49A0-9668-801B5034F2B3Q38397747-AB3A0B4E-B9AF-4DBC-A3C5-D9E9120E7E82Q38553929-948D41BA-E53B-4968-9EC7-F63F3F8FDF58Q38672722-5AFB434F-6BED-44CC-97C7-6CA2F85A1203Q38700987-1E2C307B-D997-4800-B776-80E42C34D005
P2860
A critical evaluation of in vitro cell culture models for high-throughput drug screening and toxicity.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
A critical evaluation of in vi ...... t drug screening and toxicity.
@ast
A critical evaluation of in vi ...... t drug screening and toxicity.
@en
A critical evaluation of in vi ...... t drug screening and toxicity.
@nl
type
label
A critical evaluation of in vi ...... t drug screening and toxicity.
@ast
A critical evaluation of in vi ...... t drug screening and toxicity.
@en
A critical evaluation of in vi ...... t drug screening and toxicity.
@nl
prefLabel
A critical evaluation of in vi ...... t drug screening and toxicity.
@ast
A critical evaluation of in vi ...... t drug screening and toxicity.
@en
A critical evaluation of in vi ...... t drug screening and toxicity.
@nl
P2093
P1476
A critical evaluation of in vi ...... t drug screening and toxicity.
@en
P2093
Anna Astashkina
Brenda Mann
David W Grainger
P304
P356
10.1016/J.PHARMTHERA.2012.01.001
P577
2012-01-10T00:00:00Z