cAMP sensitivity of HCN pacemaker channels determines basal heart rate but is not critical for autonomic rate control. - Wikidata - awgldk - TriplyDB

cAMP sensitivity of HCN pacemaker channels determines basal heart rate but is not critical for autonomic rate control.

cAMP sensitivity of HCN pacemaker channels determines basal heart rate but is not critical for autonomic rate control.

http://www.wikidata.org/entity/Q34130292

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Hyperpolarization-activated current, If, in mathematical models of rabbit sinoatrial node pacemaker cells Modern concepts concerning the origin of the heartbeat.Pacemaker activity of the human sinoatrial node: an update on the effects of mutations in HCN4 on the hyperpolarization-activated current Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish.Pacemaker current inhibition in experimental human cardiac sympathetic activation: a double-blind, randomized, crossover study.A long lasting β1 adrenergic receptor stimulation of cAMP/protein kinase A (PKA) signal in cardiac myocytes.Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation Potential effects of intrinsic heart pacemaker cell mechanisms on dysrhythmic cardiac action potential firing The genetic basis for inherited forms of sinoatrial dysfunction and atrioventricular node dysfunction Impaired signaling intrinsic to sinoatrial node pacemaker cells affects heart rate variability during cardiac disease.Transcription factor ISL1 is essential for pacemaker development and function.Biological Heart Rate Reduction Through Genetic Suppression of Gα(s) Protein in the Sinoatrial Node.The Popeye Domain Containing Genes and cAMP Signaling Exploring HCN channels as novel drug targets.HCN4, Sinus Bradycardia and Atrial Fibrillation.HCN Channel C-Terminal Region Speeds Activation Rates Independently of Autoinhibition.Free energy landscape remodeling of the cardiac pacemaker channel explains the molecular basis of familial sinus bradycardia The HCN4 channel mutation D553N associated with bradycardia has a C-linker mediated gating defect.HCN4 pacemaker channels attenuate the parasympathetic response and stabilize the spontaneous firing of the sinoatrial node.Mutation in S6 domain of HCN4 channel in patient with suspected Brugada syndrome modifies channel function.Rescuing cardiac automaticity in L-type Cav1.3 channelopathies and beyond.The Popeye Domain Containing Genes and Their Function as cAMP Effector Proteins in Striated Muscle.

P2860

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P2860

cAMP sensitivity of HCN pacemaker channels determines basal heart rate but is not critical for autonomic rate control.

http://www.wikidata.org/entity/Q34130292

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

cAMP sensitivity of HCN pacema ...... al for autonomic rate control.

@ast

cAMP sensitivity of HCN pacema ...... al for autonomic rate control.

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cAMP sensitivity of HCN pacema ...... al for autonomic rate control.

@nl

type

label

cAMP sensitivity of HCN pacema ...... al for autonomic rate control.

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cAMP sensitivity of HCN pacema ...... al for autonomic rate control.

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cAMP sensitivity of HCN pacema ...... al for autonomic rate control.

@nl

prefLabel

cAMP sensitivity of HCN pacema ...... al for autonomic rate control.

@ast

cAMP sensitivity of HCN pacema ...... al for autonomic rate control.

@en

cAMP sensitivity of HCN pacema ...... al for autonomic rate control.

@nl

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CIRCEP.110.949768

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Circulation: Arrhythmia and Electrophysiology

P1476

cAMP sensitivity of HCN pacema ...... al for autonomic rate control.

@en

P2093

Andreas Draguhn

http://www.w3.org/2001/XMLSchema#string

Claus Bruehl

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Dierk Thomas

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Hugo A Katus

http://www.w3.org/2001/XMLSchema#string

Jörg Zehelein

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Michael Koenen

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Nana Duhme

http://www.w3.org/2001/XMLSchema#string

Patrick A Schweizer

http://www.w3.org/2001/XMLSchema#string

Rüdiger Becker

http://www.w3.org/2001/XMLSchema#string

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542-552

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scholarly article

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10.1161/CIRCEP.110.949768

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5

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3

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2010-08-07T00:00:00Z

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20693575

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