A mutant of Burkholderia pseudomallei, auxotrophic in the branched chain amino acid biosynthetic pathway, is attenuated and protective in a murine model of melioidosis.
about
Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets?Melioidosis: epidemiology, pathophysiology, and management.Development of Burkholderia mallei and pseudomallei vaccinesConsensus on the development of vaccines against naturally acquired melioidosisMelioidosis vaccines: a systematic review and appraisal of the potential to exploit biodefense vaccines for public health purposesStructural insights into WcbI, a novel polysaccharide-biosynthesis enzymeContinuing evolution of Burkholderia mallei through genome reduction and large-scale rearrangementsStrategies toward vaccines against Burkholderia mallei and Burkholderia pseudomallei.Recombinant Salmonella Expressing Burkholderia mallei LPS O Antigen Provides Protection in a Murine Model of Melioidosis and Glanders.Burkholderia pseudomallei Colony Morphotypes Show a Synchronized Metabolic Pattern after Acute Infection.Phenotypic and functional characterization of human memory T cell responses to Burkholderia pseudomallei.Within-Host Evolution of Burkholderia pseudomallei during Chronic Infection of Seven Australasian Cystic Fibrosis Patients.Genome wide transcriptome profiling of a murine acute melioidosis model reveals new insights into how Burkholderia pseudomallei overcomes host innate immunityAn avirulent Burkholderia pseudomallei ∆purM strain with atypical type B LPS: expansion of the toolkit for biosafe studies of melioidosis.A Burkholderia pseudomallei deltapurM mutant is avirulent in immunocompetent and immunodeficient animals: candidate strain for exclusion from select-agent listsHumoral and cell-mediated adaptive immune responses are required for protection against Burkholderia pseudomallei challenge and bacterial clearance postinfection.Immunogenic Consensus Sequence T helper Epitopes for a Pan-Burkholderia Biodefense Vaccine.Integrative genomic analysis identifies isoleucine and CodY as regulators of Listeria monocytogenes virulenceIdentification of Burkholderia pseudomallei genes required for the intracellular life cycle and in vivo virulence.Evaluation of surrogate animal models of melioidosisCombining vaccination and postexposure CpG therapy provides optimal protection against lethal sepsis in a biodefense model of human melioidosis.CD4+ T-cell immunity to the Burkholderia pseudomallei ABC transporter LolC in melioidosisA thrombomodulin mutation that impairs active protein C generation is detrimental in severe pneumonia-derived gram-negative sepsis (melioidosis).A vaccine for tularaemia.Melioidosis vaccines.Global map of growth-regulated gene expression in Burkholderia pseudomallei, the causative agent of melioidosis.Development of vaccines against burkholderia pseudomallei.A naturally derived outer-membrane vesicle vaccine protects against lethal pulmonary Burkholderia pseudomallei infection.Characterization of Burkholderia pseudomallei Strains Using a Murine Intraperitoneal Infection Model and In Vitro Macrophage Assays.Whole-genome sequencing of Bacillus subtilis XF-1 reveals mechanisms for biological control and multiple beneficial properties in plants.Characterization of the Burkholderia pseudomallei K96243 capsular polysaccharide I coding region.Fate of a Burkholderia pseudomallei lipopolysaccharide mutant in the mouse macrophage cell line RAW 264.7: possible role for the O-antigenic polysaccharide moiety of lipopolysaccharide in internalization and intracellular survival.Identification of a LolC homologue in Burkholderia pseudomallei, a novel protective antigen for melioidosisImmunogenic recombinant Burkholderia pseudomallei MprA serine protease elicits protective immunity in miceRole of RelA and SpoT in Burkholderia pseudomallei virulence and immunityDevelopment of capsular polysaccharide-based glycoconjugates for immunization against melioidosis and glandersTwo stable variants of Burkholderia pseudomallei strain MSHR5848 express broadly divergent in vitro phenotypes associated with their virulence differences.Structural diversity of Burkholderia pseudomallei lipopolysaccharides affects innate immune signaling.Burkholderia vaccines: are we moving forward?Growth inhibition of pathogenic bacteria by sulfonylurea herbicides
P2860
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P2860
A mutant of Burkholderia pseudomallei, auxotrophic in the branched chain amino acid biosynthetic pathway, is attenuated and protective in a murine model of melioidosis.
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A mutant of Burkholderia pseud ...... a murine model of melioidosis.
@ast
A mutant of Burkholderia pseud ...... a murine model of melioidosis.
@en
A mutant of Burkholderia pseud ...... a murine model of melioidosis.
@nl
type
label
A mutant of Burkholderia pseud ...... a murine model of melioidosis.
@ast
A mutant of Burkholderia pseud ...... a murine model of melioidosis.
@en
A mutant of Burkholderia pseud ...... a murine model of melioidosis.
@nl
prefLabel
A mutant of Burkholderia pseud ...... a murine model of melioidosis.
@ast
A mutant of Burkholderia pseud ...... a murine model of melioidosis.
@en
A mutant of Burkholderia pseud ...... a murine model of melioidosis.
@nl
P2093
P2860
P1476
A mutant of Burkholderia pseud ...... a murine model of melioidosis.
@en
P2093
P C F Oyston
R W Titball
P2860
P304
P356
10.1128/IAI.70.9.5290-5294.2002
P407
P577
2002-09-01T00:00:00Z