Polymorphisms in the multiple drug resistance protein 1 and in P-glycoprotein 1 are associated with time to event outcomes in patients with advanced multiple myeloma treated with bortezomib and pegylated liposomal doxorubicin.

Polymorphisms in the multiple drug resistance protein 1 and in P-glycoprotein 1 are associated with time to event outcomes in patients with advanced multiple myeloma treated with bortezomib and pegylated liposomal doxorubicin.

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http://www.wikidata.org/entity/Q34130459

Q34130459

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Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms.Characterisation of the clinical pharmacokinetics of actinomycin D and the influence of ABCB1 pharmacogenetic variation on actinomycin D disposition in children with cancer.Bortezomib in multiple myeloma: systematic review and clinical considerations.A comprehensive investigation on common polymorphisms in the MDR1/ABCB1 transporter gene and susceptibility to colorectal cancer.Interaction of innovative small molecule drugs used for cancer therapy with drug transporters.Efflux transporter variants as predictors of drug toxicity in lung cancer patients: systematic review and meta-analysis.CNS uptake of bortezomib is enhanced by P-glycoprotein inhibition: implications for spinal muscular atrophy Genetic variations in multiple myeloma II: association with effect of treatment.Pharmacogenetics of genes across the doxorubicin pathway.Pegylated liposomal doxorubicin: a review of its use in metastatic breast cancer, ovarian cancer, multiple myeloma and AIDS-related Kaposi's sarcoma.Latest advances and current challenges in the treatment of multiple myeloma.Emerging biological insights and novel treatment strategies in multiple myeloma.Perspectives in the treatment of multiple myeloma.The role of P-glycoprotein in drug resistance in multiple myeloma.MRP1 and its role in anticancer drug resistance.Mechanisms of Drug Resistance in Relapse and Refractory Multiple Myeloma.Predictive value of ABCB1 polymorphisms G2677T/A, C3435T, and their haplotype in small cell lung cancer patients treated with chemotherapy.Pharmacogenetic study of the impact of ABCB1 single-nucleotide polymorphisms on lenalidomide treatment outcomes in patients with multiple myeloma: results from a phase IV observational study and subsequent phase II clinical trial.Association of MDR1 single-nucleotide polymorphisms and haplotype variants with multiple myeloma in Chinese Jiangsu Han population.

P2860

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P2860

Polymorphisms in the multiple drug resistance protein 1 and in P-glycoprotein 1 are associated with time to event outcomes in patients with advanced multiple myeloma treated with bortezomib and pegylated liposomal doxorubicin.

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http://www.wikidata.org/entity/Q34130459

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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