Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways.
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Flavokawain B, a kava chalcone, inhibits growth of human osteosarcoma cells through G2/M cell cycle arrest and apoptosisKava, the anxiolytic herb: back to basics to prevent liver injury?Hepatotoxicity Induced by "the 3Ks": Kava, Kratom and KhatDihydro-5,6-dehydrokavain (DDK) from Alpinia zerumbet: Its Isolation, Synthesis, and CharacterizationMolecular targeted approaches to cancer therapy and prevention using chalconesMeasuring the chemical and cytotoxic variability of commercially available kava (Piper methysticum G. Forster)Kava and kava hepatotoxicity: requirements for novel experimental, ethnobotanical and clinical studies based on a review of the evidence.Methysticin and 7,8-dihydromethysticin are two major kavalactones in kava extract to induce CYP1A1.Flavokawains a and B in kava, not dihydromethysticin, potentiate acetaminophen-induced hepatotoxicity in C57BL/6 mice.Dietary feeding of Flavokawain A, a Kava chalcone, exhibits a satisfactory safety profile and its association with enhancement of phase II enzymes in mice.The role of chalcones in suppression of NF-κB-mediated inflammation and cancer.Flavokawain B, a novel, naturally occurring chalcone, exhibits robust apoptotic effects and induces G2/M arrest of a uterine leiomyosarcoma cell line.Crude Extracts, Flavokawain B and Alpinetin Compounds from the Rhizome of Alpinia mutica Induce Cell Death via UCK2 Enzyme Inhibition and in Turn Reduce 18S rRNA Biosynthesis in HT-29 Cells.Kava blocks 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in association with reducing O6-methylguanine DNA adduct in A/J miceHormetics: dietary triggers of an adaptive stress response.The flavokawains: uprising medicinal chalcones.The In Vitro and In Vivo Antiangiogenic Effects of Flavokawain B.Chalcone flavokawain B induces autophagic-cell death via reactive oxygen species-mediated signaling pathways in human gastric carcinoma and suppresses tumor growth in nude mice.Insulin and IGFs enhance hepatocyte differentiation from human embryonic stem cells via the PI3K/AKT pathway.Toxicokinetics of kava.Gene Expression Analysis Reveals the Concurrent Activation of Proapoptotic and Antioxidant-Defensive Mechanisms in Flavokawain B-Treated Cervical Cancer HeLa Cells.Kavain Involvement in LPS-Induced Signaling Pathways.In Silico Discovery of Potential Uridine-Cytidine Kinase 2 Inhibitors from the Rhizome of Alpinia mutica.
P2860
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P2860
Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways.
description
2010 nî lūn-bûn
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2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Flavokawain B, the hepatotoxic ...... B and MAPK signaling pathways.
@ast
Flavokawain B, the hepatotoxic ...... B and MAPK signaling pathways.
@en
Flavokawain B, the hepatotoxic ...... B and MAPK signaling pathways.
@nl
type
label
Flavokawain B, the hepatotoxic ...... B and MAPK signaling pathways.
@ast
Flavokawain B, the hepatotoxic ...... B and MAPK signaling pathways.
@en
Flavokawain B, the hepatotoxic ...... B and MAPK signaling pathways.
@nl
prefLabel
Flavokawain B, the hepatotoxic ...... B and MAPK signaling pathways.
@ast
Flavokawain B, the hepatotoxic ...... B and MAPK signaling pathways.
@en
Flavokawain B, the hepatotoxic ...... B and MAPK signaling pathways.
@nl
P2093
P2860
P356
P1433
P1476
Flavokawain B, the hepatotoxic ...... aB and MAPK signaling pathways
@en
P2093
Bo-Yang Yu
David Piwnica-Worms
Ji-Hua Liu
Ling-Ling Feng
Samuel X Qiu
Shimon Gross
Vijay Sharma
P2860
P304
P356
10.1096/FJ.10-163311
P407
P50
P577
2010-08-09T00:00:00Z