T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
about
Effector, Memory, and Dysfunctional CD8(+) T Cell Fates in the Antitumor Immune ResponseTargeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor ImmunityThe POSH/JIP-1 scaffold network regulates TCR-mediated JNK1 signals and effector function in CD8(+) T cells.Analysis of transcription factors expressed at the anterior mouse limb bud.Role of tumor suppressor TSC1 in regulating antigen-specific primary and memory CD8 T cell responses to bacterial infection.Inflammation programs self-reactive CD8+ T cells to acquire T-box-mediated effector function but does not prevent deletional toleranceTIM-3 expression characterizes regulatory T cells in tumor tissues and is associated with lung cancer progressionEomesodermin of atlantic salmon: an important regulator of cytolytic gene and interferon gamma expression in spleen lymphocytesAge and CD161 expression contribute to inter-individual variation in interleukin-23 response in CD8+ memory human T cellsThe Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells.Integrated analyses of DNA methylation and hydroxymethylation reveal tumor suppressive roles of ECM1, ATF5, and EOMES in human hepatocellular carcinomaTumoral expression of IL-33 inhibits tumor growth and modifies the tumor microenvironment through CD8+ T and NK cellsT-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells.Checkpoint blockade immunotherapy relies on T-bet but not Eomes to induce effector function in tumor-infiltrating CD8+ T cells.Tc17 cells in patients with uterine cervical cancerTargeting miR-23a in CD8+ cytotoxic T lymphocytes prevents tumor-dependent immunosuppression.Heteroclitic XBP1 peptides evoke tumor-specific memory cytotoxic T lymphocytes against breast cancer, colon cancer, and pancreatic cancer cells.Synergy of brief activation of CD8 T-cells in the presence of IL-12 and adoptive transfer into lymphopenic hosts promotes tumor clearance and anti-tumor memory.Distribution, characterization, and induction of CD8+ regulatory T cells and IL-17-producing CD8+ T cells in nasopharyngeal carcinoma.IRF4 Regulates the Ratio of T-Bet to Eomesodermin in CD8+ T Cells Responding to Persistent LCMV Infection.Vaccination Produces CD4 T Cells with a Novel CD154-CD40-Dependent Cytolytic MechanismCCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cellsProgress in multiple sclerosis genetics.Eomesodermin(lo) CTLA4(hi) Alloreactive CD8+ Memory T Cells Are Associated With Prolonged Renal Transplant Survival Induced by Regulatory Dendritic Cell Infusion in CTLA4 Immunoglobulin-Treated Nonhuman Primates.T-bet expression in CD8+ T cells associated with chronic hepatitis B virus infection.Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes.Antigen spreading-induced CD8+T cells confer protection against the lethal challenge of wild-type malignant mesothelioma by eliminating myeloid-derived suppressor cells.PD-1 Blockade Boosts Radiofrequency Ablation-Elicited Adaptive Immune Responses against Tumor.Ipilimumab reshapes T cell memory subsets in melanoma patients with clinical response.Lenalidomide Polarizes Th1-specific Anti-tumor Immune Response and Expands XBP1 Antigen-Specific Central Memory CD3(+)CD8(+) T cells against Various Solid Tumors.Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes.Therapeutic PD-1 pathway blockade augments with other modalities of immunotherapy T-cell function to prevent immune decline in ovarian cancerInterleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice.The Role of IL-33-Dependent Inflammation in the Tumor Microenvironment.Virus-specific CD4 and CD8 T cell responses in the absence of Th1-associated transcription factorsTbr2 is required to generate a neural circuit mediating the pupillary light reflex.Eomesodermin is required for antitumor immunity mediated by 4-1BB-agonist immunotherapy.Tc17 Cells in Immunity and Systemic Autoimmunity.IL-17A-producing CD8(+)T cells as therapeutic targets in autoimmunity.Higher numbers of T-bet(+) intratumoral lymphoid cells correlate with better survival in gastric cancer.
P2860
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P2860
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
@ast
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
@en
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
@nl
type
label
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
@ast
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
@en
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
@nl
prefLabel
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
@ast
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
@en
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses.
@nl
P2093
P356
P1476
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses
@en
P2093
Binfeng Lu
Changyou Li
Elizabeth Chen
Songguang Ju
Xueguang Zhang
P304
P356
10.4049/JIMMUNOL.1000749
P407
P577
2010-08-16T00:00:00Z