CYP24A1 inhibition enhances the antitumor activity of calcitriol.
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Calcitriol in Combination Therapy for Prostate Cancer: Pharmacokinetic and Pharmacodynamic InteractionsPerspectives of differentiation therapies of acute myeloid leukemia: the search for the molecular basis of patients' variable responses to 1,25-dihydroxyvitamin d and vitamin d analogsCYP17 inhibitors for prostate cancer therapyAstemizole synergizes calcitriol antiproliferative activity by inhibiting CYP24A1 and upregulating VDR: a novel approach for breast cancer therapyNovel alkynylphosphonate analogue of calcitriol with potent antiproliferative effects in cancer cells and lack of calcemic activity.Vitamin D: considerations in the continued development as an agent for cancer prevention and therapy.Vitamin D metabolism and action in the prostate: implications for health and disease.VDR activity is differentially affected by Hic-5 in prostate cancer and stromal cells.CYP24A1 exacerbated activity during diabetes contributes to kidney tubular apoptosis via caspase-3 increased expression and activation.Inhibition of protein kinase CK2 reduces Cyp24a1 expression and enhances 1,25-dihydroxyvitamin D(3) antitumor activity in human prostate cancer cells.Inhibitory effects of calcitriol on the growth of MCF-7 breast cancer xenografts in nude mice: selective modulation of aromatase expression in vivo.Vitamin d, sunlight and prostate cancer riskAberrant DNA methylation of drug metabolism and transport genes in nodular goiterA Functional and Putative Physiological Role of Calcitriol in Patched1/Smoothened Interaction.Vitamin D resistance and colon cancer prevention.Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis.CYP24 inhibition as a therapeutic target in FGF23-mediated renal phosphate wasting disordersImpaired vitamin D metabolism in CKDHigh throughput LC-MS/MS method for the simultaneous analysis of multiple vitamin D analytes in serum.Inecalcitol, an analog of 1,25D3, displays enhanced antitumor activity through the induction of apoptosis in a squamous cell carcinoma model systemProgesterone potentiates the growth inhibitory effects of calcitriol in endometrial cancer via suppression of CYP24A1.The role of vitamin D in cancer prevention and treatment.The role of vitamin D in cancer prevention and treatment.Vitamin D in cancer chemoprevention.Vitamin D analogue: potent antiproliferative effects on cancer cell lines and lack of hypercalcemic activity.Increased CYP24A1 expression is associated with BRAF(V600E) mutation and advanced stages in papillary thyroid carcinoma.The effect of vitamin D3 and ketoconazole combination on VDR-mediated P-gp expression and function in human colon adenocarcinoma cells: implications in drug disposition and resistance.Vitamin D in combination cancer treatment.Take another CYP: confirming a novel mechanism for "idiopathic" hypercalcemia.The cellular selection between apoptosis and autophagy: roles of vitamin D, glucose and immune response in diabetic nephropathy.Exploring vitamin D metabolism and function in cancer.Dose Escalation of Vitamin D3 Yields Similar Cryosurgical Outcome to Single Dose Exposure in a Prostate Cancer Model.Regulation of CYP27B1 and CYP24A1 hydroxylases limits cell-autonomous activation of vitamin D in dendritic cells.Temporal changes in tissue 1α,25-dihydroxyvitamin D3, vitamin D receptor target genes, and calcium and PTH levels after 1,25(OH)2D3 treatment in mice.Vitamin D in prostate cancer.
P2860
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P2860
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
@ast
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
@en
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
@nl
type
label
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
@ast
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
@en
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
@nl
prefLabel
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
@ast
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
@en
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
@nl
P2093
P2860
P356
P1433
P1476
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
@en
P2093
Candace S Johnson
Donald L Trump
Josephia R Muindi
Kristie L Engler
Rui-Xian Kong
Wei-Dong Yu
P2860
P304
P356
10.1210/EN.2009-1156
P407
P577
2010-06-30T00:00:00Z