SL65.0155, a novel 5-hydroxytryptamine(4) receptor partial agonist with potent cognition-enhancing properties.
about
5-HT4 receptor agonists increase sAPPalpha levels in the cortex and hippocampus of male C57BL/6j miceRole of the serotonin 5-HT(2A) receptor in learningRapamycin-sensitive signalling in long-term consolidation of auditory cortex-dependent memoryA biphasic and brain-region selective down-regulation of cyclic adenosine monophosphate concentrations supports object recognition in the ratConstitutive dimerization of human serotonin 5-HT4 receptors in living cells.Hyperfunction of muscarinic receptor maintains long-term memory in 5-HT4 receptor knock-out miceE-6801, a 5-HT6 receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat.Blockade of dopamine D₃ but not D₂ receptors reverses the novel object discrimination impairment produced by post-weaning social isolation: implications for schizophrenia and its treatment.Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents.Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.Alzheimer's disease and age-related memory decline (preclinical)Evaluation in monkey of two candidate PET radioligands, [(11) C]RX-1 and [(18) F]RX-2, for imaging brain 5-HT4 receptorsAging in Sensory and Motor Neurons Results in Learning Failure in Aplysia californica.Age-related deficits in synaptic plasticity rescued by activating PKA or PKC in sensory neurons of Aplysia californica.Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation.Synthesis and structure-affinity relationships of selective high-affinity 5-HT(4) receptor antagonists: application to the design of new potential single photon emission computed tomography tracers.Role of serotonin in Alzheimer's disease: a new therapeutic target?The role of serotonin in memory: interactions with neurotransmitters and downstream signaling.Modulating 5-HT4 and 5-HT6 receptors in Alzheimer's disease treatment.Multitarget strategies in Alzheimer's disease: benefits and challenges on the road to therapeutics.Co-modulation of an allosteric modulator of nicotinic receptor-cholinesterase inhibitor (galantamine) and a 5-HT4 receptor agonist (RS-67333): effect on scopolamine-induced memory deficit in the mouse.Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors. Distinct molecular events with different GRK2 requirements.Serotonin 5-HT4 receptors and forebrain cholinergic system: receptor expression in identified cell populations.The 5-hydroxytryptamine4 receptor exhibits frequency-dependent properties in synaptic plasticity and behavioural metaplasticity in the hippocampal CA1 region in vivo.In-vivo rat striatal 5-HT4 receptor occupancy using non-radiolabelled SB207145.
P2860
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P2860
SL65.0155, a novel 5-hydroxytryptamine(4) receptor partial agonist with potent cognition-enhancing properties.
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
SL65.0155, a novel 5-hydroxytr ...... ognition-enhancing properties.
@ast
SL65.0155, a novel 5-hydroxytr ...... ognition-enhancing properties.
@en
SL65.0155, a novel 5-hydroxytr ...... ognition-enhancing properties.
@nl
type
label
SL65.0155, a novel 5-hydroxytr ...... ognition-enhancing properties.
@ast
SL65.0155, a novel 5-hydroxytr ...... ognition-enhancing properties.
@en
SL65.0155, a novel 5-hydroxytr ...... ognition-enhancing properties.
@nl
prefLabel
SL65.0155, a novel 5-hydroxytr ...... ognition-enhancing properties.
@ast
SL65.0155, a novel 5-hydroxytr ...... ognition-enhancing properties.
@en
SL65.0155, a novel 5-hydroxytr ...... ognition-enhancing properties.
@nl
P2093
P50
P356
P1476
SL65.0155, a novel 5-hydroxytr ...... ognition-enhancing properties.
@en
P2093
Aline Dumuis
Alistair Lochead
Bernard Scatton
Dominique Caille
Elee Duconseille
Jean-Paul Terranova
Joel Bockaert
Olivier E Bergis
Pascal George
Paul C Moser
P304
P356
10.1124/JPET.102.034249
P407
P577
2002-08-01T00:00:00Z