ABT-737 overcomes resistance to immunotoxin-mediated apoptosis and enhances the delivery of pseudomonas exotoxin-based proteins to the cell cytosol.
about
Mechanisms of drug resistance in colon cancer and its therapeutic strategiesThe development of immunoconjugates for targeted cancer therapyMechanisms of action of therapeutic antibodies for cancerSynergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanomaChemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins.Emerging Bcl-2 inhibitors for the treatment of cancer.Cytolethal distending toxin B as a cell-killing component of tumor-targeted anthrax toxin fusion proteins.MicroRNA-195 promotes apoptosis in mouse podocytes via enhanced caspase activity driven by BCL2 insufficiency.Combination treatments with the PKC inhibitor, enzastaurin, enhance the cytotoxicity of the anti-mesothelin immunotoxin, SS1P.Killing of resistant cancer cells with low Bak by a combination of an antimesothelin immunotoxin and a TRAIL Receptor 2 agonist antibody.A guide to taming a toxin--recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer.Targeting malignant B cells with an immunotoxin against ROR1Antigen shedding may improve efficiencies for delivery of antibody-based anticancer agents in solid tumorsThe transferrin receptor and the targeted delivery of therapeutic agents against cancer.Combination treatments with ABT-263 and an immunotoxin produce synergistic killing of ABT-263-resistant small cell lung cancer cell lines.Antibody-based therapeutics for the treatment of human B cell malignanciesImmunotoxins: the role of the toxin.Antitumor effects of immunotoxins are enhanced by lowering HCK or treatment with SRC kinase inhibitors.Enhancing immunotoxin cell-killing activity via combination therapy with ABT-737.Targeting a Cancer-Specific Epitope of the Epidermal Growth Factor Receptor in Triple-Negative Breast Cancer.Methylseleninic acid potentiates multiple types of cancer cells to ABT-737-induced apoptosis by targeting Mcl-1 and Bad.Clinical targeting recombinant immunotoxins for cancer therapyImproved Protein Toxin Delivery Based on ATTEMPTS Systems.Essential role for Bim in mediating the apoptotic and antitumor activities of immunotoxins.
P2860
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P2860
ABT-737 overcomes resistance to immunotoxin-mediated apoptosis and enhances the delivery of pseudomonas exotoxin-based proteins to the cell cytosol.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
ABT-737 overcomes resistance t ...... proteins to the cell cytosol.
@ast
ABT-737 overcomes resistance t ...... proteins to the cell cytosol.
@en
ABT-737 overcomes resistance t ...... proteins to the cell cytosol.
@nl
type
label
ABT-737 overcomes resistance t ...... proteins to the cell cytosol.
@ast
ABT-737 overcomes resistance t ...... proteins to the cell cytosol.
@en
ABT-737 overcomes resistance t ...... proteins to the cell cytosol.
@nl
prefLabel
ABT-737 overcomes resistance t ...... proteins to the cell cytosol.
@ast
ABT-737 overcomes resistance t ...... proteins to the cell cytosol.
@en
ABT-737 overcomes resistance t ...... proteins to the cell cytosol.
@nl
P2093
P2860
P1476
ABT-737 overcomes resistance t ...... d proteins to the cell cytosol
@en
P2093
Antonella Antignani
Ashima K Sharma
David J Fitzgerald
Elizabeth Moskatel
Gal Ben-Josef
Roberta Traini
P2860
P304
P356
10.1158/1535-7163.MCT-10-0257
P577
2010-06-29T00:00:00Z