Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production. - Wikidata - awgldk - TriplyDB

Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production.

Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production.

http://www.wikidata.org/entity/Q34147790

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10E,12Z-conjugated linoleic acid impairs adipocyte triglyceride storage by enhancing fatty acid oxidation, lipolysis, and mitochondrial reactive oxygen species Molecular targets for 17α-ethynyl-5-androstene-3β,7β,17β-triol, an anti-inflammatory agent derived from the human metabolome Macrophage-secreted factors promote a profibrotic phenotype in human preadipocytes Antiobesity mechanisms of action of conjugated linoleic acid.Moderate doses of conjugated linoleic acid reduce fat gain, maintain insulin sensitivity without impairing inflammatory adipose tissue status in mice fed a high-fat diet In vitro study of the effect of diesterified alkoxyglycerols with conjugated linoleic acid on adipocyte inflammatory mediators.trans-10,cis-12-Conjugated linoleic acid instigates inflammation in human adipocytes compared with preadipocytes Inflammation and insulin resistance induced by trans-10, cis-12 conjugated linoleic acid depend on intracellular calcium levels in primary cultures of human adipocytes t10,c12-CLA decreases adiposity in peripubertal mice without dose-related detrimental effects on mammary development, inflammation status, and metabolism Cross regulation of sirtuin 1, AMPK, and PPARγ in conjugated linoleic acid treated adipocytes.JNK inhibition by SP600125 attenuates trans-10, cis-12 conjugated linoleic acid-mediated regulation of inflammatory and lipogenic gene expression Obesity, insulin resistance and free fatty acids.Adipose tissue ATP binding cassette transporter A1 contributes to high-density lipoprotein biogenesis in vivo.Trans-10, cis-12 conjugated linoleic acid decreases de novo lipid synthesis in human adipocytes Low level of trans-10, cis-12 conjugated linoleic acid decreases adiposity and increases browning independent of inflammatory signaling in overweight Sv129 mice Sphingolipids are required for efficient triacylglycerol loss in conjugated linoleic Acid treated adipocytes.Oleic acid attenuates trans-10,cis-12 conjugated linoleic acid-mediated inflammatory gene expression in human adipocytes.trans-10,cis-12 conjugated linoleic acid promotes bone formation by inhibiting adipogenesis by peroxisome proliferator activated receptor-γ-dependent mechanisms and by directly enhancing osteoblastogenesis from bone marrow mesenchymal stem cells.Conjugated linoleic acid intake in humans: a systematic review focusing on its effect on body composition, glucose, and lipid metabolism.Diacylglycerol kinase inhibitor R59022 attenuates conjugated linoleic acid-mediated inflammation in human adipocytes.Obesity-related upregulation of monocyte chemotactic factors in adipocytes: involvement of nuclear factor-kappaB and c-Jun NH2-terminal kinase pathways.The phospholipase C inhibitor U73122 attenuates trans-10, cis-12 conjugated linoleic acid-mediated inflammatory signaling and insulin resistance in human adipocytes.Conjugated linoleic acid-mediated inflammation and insulin resistance in human adipocytes are attenuated by resveratrol.Oxidized LDL impair adipocyte response to insulin by activating serine/threonine kinases.Bioactive dietary long-chain fatty acids: emerging mechanisms of action.The effect of trans-10, cis-12 conjugated linoleic acid on gene expression profiles related to lipid metabolism in human intestinal-like Caco-2 cells.Mammary gland development--It's not just about estrogen Dietary determinants of subclinical inflammation, dyslipidemia and components of the metabolic syndrome in overweight children: a review.Isomer-specific effects of CLA on gene expression in human adipose tissue depending on PPARgamma2 P12A polymorphism: a double blind, randomized, controlled cross-over study.Influence of conjugated linoleic acids on functional properties of vascular cells.Implication of conjugated linoleic acid (CLA) in human health.Gene expression silencing with 'specific' small interfering RNA goes beyond specificity - a study of key parameters to take into account in the onset of small interfering RNA off-target effects.Trans-10, cis-12 conjugated linoleic acid activates the integrated stress response pathway in adipocytes.Dairy nutrients and their effect on inflammatory profile in molecular studies.Conjugated linoleic acid inhibits osteoclast differentiation of RAW264.7 cells by modulating RANKL signaling.PPARs and lipid ligands in inflammation and metabolism.Dietary t10,c12-CLA but not c9,t11 CLA reduces adipocyte size in the absence of changes in the adipose renin-angiotensin system in fa/fa Zucker rats.Absorption and metabolism of cis-9,trans-11-CLA and of its oxidation product 9,11-furan fatty acid by Caco-2 cells.Trans-10, cis-12 conjugated linoleic acid antagonizes ligand-dependent PPARgamma activity in primary cultures of human adipocytes.FFA-induced adipocyte inflammation and insulin resistance: involvement of ER stress and IKKβ pathways.

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P2860

Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production.

http://www.wikidata.org/entity/Q34147790

description

2005 nî lūn-bûn

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2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Conjugated linoleic acid promo ...... dependent cytokine production.

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Conjugated linoleic acid promo ...... dependent cytokine production.

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Conjugated linoleic acid promo ...... dependent cytokine production.

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type

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Conjugated linoleic acid promo ...... dependent cytokine production.

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Conjugated linoleic acid promo ...... dependent cytokine production.

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Conjugated linoleic acid promo ...... dependent cytokine production.

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Conjugated linoleic acid promo ...... dependent cytokine production.

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Conjugated linoleic acid promo ...... dependent cytokine production.

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Journal of Biological Chemistry

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Conjugated linoleic acid promo ...... -dependent cytokine production

@en

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J Mark Brown

http://www.w3.org/2001/XMLSchema#string

J Nathan Provo

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Michael K McIntosh

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Robin Hopkins

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P2860

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Obesity is associated with macrophage accumulation in adipose tissue

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B

Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade

Shaping the nuclear action of NF-kappaB

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural views.

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10.1074/JBC.M508159200

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46

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280

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