Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
about
Sigma receptors as potential therapeutic targets for neuroprotectionBiomarkers in preclinical cancer imaging.The σ2 receptor: a novel protein for the imaging and treatment of cancer.Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.Ether modifications to 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine (SA4503): effects on binding affinity and selectivity for sigma receptors and monoamine transporters.Fluorescent derivatives of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) as a tool for uptake and cellular localization studies in pancreatic tumor cells.Characterization of interactions of 4-nitrophenylpropyl-N-alkylamine with ς receptors.Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors.Lysosomal membrane permeabilization is an early event in Sigma-2 receptor ligand mediated cell death in pancreatic cancer.Sigma receptors [σRs]: biology in normal and diseased statesPharmacological evaluation of SN79, a sigma (σ) receptor ligand, against methamphetamine-induced neurotoxicity in vivo.Interrogating tumor metabolism and tumor microenvironments using molecular positron emission tomography imaging. Theranostic approaches to improve therapeutics.Synthesis and biological characterisation of 18F-SIG343 and 18F-SIG353, novel and high selectivity σ2 radiotracers, for tumour imaging properties.Selective sigma-1 receptor antagonists for the treatment of pain.Development of (18)F-labeled radiotracers for neuroreceptor imaging with positron emission tomographyRadioiodination and preclinical evaluation of 4-benzyl-1-(3-[125I]-iodobenzylsulfonyl)piperidine as a breast tumor imaging tracer in mouse.The Differentiation of Skin Mesenchymal Stem Cells Towards a Schwann Cell Phenotype: Impact of Sigma-1 Receptor Activation.2-Aminopyridine derivatives as potential σ(2) receptor antagonists.SV119-gold nanocage conjugates: a new platform for targeting cancer cells via sigma-2 receptorsInhibitory effects of sigma-2 receptor agonists on T lymphocyte activation.Radiosynthesis and in vivo evaluation of a novel σ1 selective PET ligand.Synthesis and in vitro evaluation of tetrahydroisoquinolines with pendent aromatics as sigma-2 (σ2) selective ligands.Dose-dependent sigma-1 receptor occupancy by donepezil in rat brain can be assessed with (11)C-SA4503 and microPET.Thiazole-Based σ1 Receptor Ligands: Diversity by Late-Stage C-H Arylation of Thiazoles, Structure-Affinity and Selectivity Relationships, and Molecular Interactions.Are sigma receptor modulators a weapon against multiple sclerosis disease?Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma.Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.Design and Investigation of a [18F]-Labeled Benzamide Derivative as a High Affinity Dual Sigma Receptor Subtype Radioligand for Prostate Tumor Imaging.Synthesis and evaluation of a (18) F-labeled 4-phenylpiperidine-4-carbonitrile radioligand for σ1 receptor imaging.4-Nitro-2,1,3-benzoxadiazole derivatives as potential fluorescent sigma receptor probes
P2860
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P2860
Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
@ast
Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
@en
Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
@nl
type
label
Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
@ast
Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
@en
Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
@nl
prefLabel
Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
@ast
Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
@en
Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
@nl
P2093
P1476
Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
@en
P2093
Anna A Rybczynska
Aren van Waarde
Kiichi Ishiwata
Nisha Ramakrishnan
Philip H Elsinga
Rudi A J O Dierckx
P304
P356
10.2174/138161210793563365
P577
2010-01-01T00:00:00Z