Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways. - Wikidata - awgldk - TriplyDB

Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.

Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.

http://www.wikidata.org/entity/Q34156507

about

Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53 Identification of tandem duplicate regulatory small RNAs in Pseudomonas aeruginosa involved in iron homeostasis Small silencing RNAs: an expanding universe MicroRNA targets in Drosophila A rapid and sensitive assay for quantification of siRNA efficiency and specificity Mutant p53 and ETS2, a Tale of Reciprocity Targeting Oncogenic Mutant p53 for Cancer Therapy A biochemical framework for RNA silencing in plants Designing siRNA that distinguish between genes that differ by a single nucleotide E2F3 is a mediator of DNA damage-induced apoptosis.Enhanced therapeutic efficacy by simultaneously targeting two genetic defects in tumors.RNAi technology: a revolutionary tool for the colorectal cancer therapeutics.Targeted knockdown of Bcl2 in tumor cells using a synthetic TRAIL 3'-UTR microRNA Drug-induced caspase 8 upregulation sensitises cisplatin-resistant ovarian carcinoma cells to rhTRAIL-induced apoptosis.Gene therapy for head and neck squamous cell carcinoma using KITENIN (KAI1 COOH-Terminal Interacting Tetraspanin)-antisense therapy.Nanogyroids incorporating multivalent lipids: enhanced membrane charge density and pore forming ability for gene silencing.RNA interference: a potent tool for gene-specific therapeutics.Development of gene-specific double-stranded RNA drugs.High-throughput gene silencing using cell arrays.Using RNAi to catch Drosophila genes in a web of interactions: insights into cancer research.RNA interference as a potential tool in the treatment of leukaemia.siRNA as a route to new cancer therapies.Epigenetic manipulation of gene expression: a toolkit for cell biologists The therapeutic potential of RNA interference.Selective killing of p53-deficient cancer cells by SP600125.Single domain antibodies for the knockdown of cytosolic and nuclear proteins.Individualised cancer therapeutics: dream or reality?Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity The role of p73 in hematological malignancies.Potential applications of RNA interference technology in the treatment of cancer.Suppression of keratoepithelin and myocilin by small interfering RNA (an American Ophthalmological Society thesis).The canonical Wnt signalling pathway and its APC partner in colon cancer development.Allele-specific silencing of mutant p53 attenuates dominant-negative and gain-of-function activities.Gene discovery in cervical cancer : towards diagnostic and therapeutic biomarkers.Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant alleles.Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins.Cationic liposome-nucleic acid complexes for gene delivery and silencing: pathways and mechanisms for plasmid DNA and siRNA.Lipid-based systemic delivery of siRNA.Preeclampsia is associated with alterations in the p53-pathway in villous trophoblast.RNAi: a potential new class of therapeutic for human genetic disease.

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Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.

http://www.wikidata.org/entity/Q34156507

description

2002 nî lūn-bûn

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2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Synthetic small inhibiting RNA ...... ions and restore p53 pathways.

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Synthetic small inhibiting RNA ...... ions and restore p53 pathways.

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Synthetic small inhibiting RNA ...... ions and restore p53 pathways.

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type

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Synthetic small inhibiting RNA ...... ions and restore p53 pathways.

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Synthetic small inhibiting RNA ...... ions and restore p53 pathways.

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Synthetic small inhibiting RNA ...... ions and restore p53 pathways.

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prefLabel

Synthetic small inhibiting RNA ...... ions and restore p53 pathways.

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Synthetic small inhibiting RNA ...... ions and restore p53 pathways.

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Synthetic small inhibiting RNA ...... ions and restore p53 pathways.

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Proceedings of the National Academy of Sciences of the United States of America

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Synthetic small inhibiting RNA ...... tions and restore p53 pathways

@en

P2093

Arlette Vervisch

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Guillermina Lozano

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Heike Lehrmann

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Irina Naguibneva

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Luis Alfonso Martinez

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P2860

p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53

Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

RNA interference is mediated by 21- and 22-nucleotide RNAs

Role for a bidentate ribonuclease in the initiation step of RNA interference

A system for stable expression of short interfering RNAs in mammalian cells

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

p53, the cellular gatekeeper for growth and division

WAF1, a potential mediator of p53 tumor suppression

Surfing the p53 network

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

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Annick Harel-Bellan

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11059884

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