Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer. - Wikidata - awgldk - TriplyDB

Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer.

Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer.

http://www.wikidata.org/entity/Q34158474

about

Androgen receptor footprint on the way to prostate cancer progression Role of the inositol polyphosphate-4-phosphatase type II Inpp4b in the generation of ovarian teratomas Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis.Androgen synthesis inhibitors in the treatment of castration-resistant prostate cancer.A pan-cancer proteomic perspective on The Cancer Genome Atlas.Epigenetic inactivation of inositol polyphosphate 4-phosphatase B (INPP4B), a regulator of PI3K/AKT signaling pathway in EBV-associated nasopharyngeal carcinoma INPP4B: the new kid on the PI3K block.PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control Estrogen receptor alpha prevents bladder cancer via INPP4B inhibited akt pathway in vitro and in vivo.Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1.An integrative analysis of PIK3CA mutation, PTEN, and INPP4B expression in terms of trastuzumab efficacy in HER2-positive breast cancer Tolerability, safety and pharmacokinetics of ridaforolimus in combination with bicalutamide in patients with asymptomatic, metastatic castration-resistant prostate cancer (CRPC).PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting.Phosphatases: the new brakes for cancer development?An ShRNA Based Genetic Screen Identified Sesn2 as a Potential Tumor Suppressor in Lung Cancer via Suppression of Akt-mTOR-p70S6K Signaling Expression of ERG protein in prostate cancer: variability and biological correlates.Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment.In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes.Expression and transcriptional profiling of the LKB1 tumor suppressor in cervical cancer cells INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas.PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma INPP4B is an oncogenic regulator in human colon cancer.Loss of PI(4,5)P2 5-Phosphatase A Contributes to Resistance of Human Melanoma Cells to RAF/MEK Inhibitors.Genomic profiling defines subtypes of prostate cancer with the potential for therapeutic stratification Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation.Alterations of INPP4B, PIK3CA and pAkt of the PI3K pathway are associated with squamous cell carcinoma of the lung.Targeting the PI3K signaling pathway in cancer therapy.Specific changes in the expression of imprinted genes in prostate cancer--implications for cancer progression and epigenetic regulation.Management of metastatic castration-resistant prostate cancer: recent advances.Phosphoinositide 3-kinase and INPP4B in human breast cancer.Role of oestrogen receptors in bladder cancer development.A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation.Phosphatidylinositolphosphate phosphatase activities and cancer.The extended human PTPome: a growing tyrosine phosphatase family.Mir-765 promotes cell proliferation by downregulating INPP4B expression in human hepatocellular carcinoma.INPP4B suppresses prostate cancer cell invasion INPP4B overexpression enhances the antitumor efficacy of PARP inhibitor AG014699 in MDA-MB-231 triple-negative breast cancer cells.Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch.

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P2860

Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer.

http://www.wikidata.org/entity/Q34158474

description

2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Decreased expression and andro ...... ene INPP4B in prostate cancer.

@ast

Decreased expression and andro ...... ene INPP4B in prostate cancer.

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Decreased expression and andro ...... ene INPP4B in prostate cancer.

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type

label

Decreased expression and andro ...... ene INPP4B in prostate cancer.

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Decreased expression and andro ...... ene INPP4B in prostate cancer.

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Decreased expression and andro ...... ene INPP4B in prostate cancer.

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Decreased expression and andro ...... ene INPP4B in prostate cancer.

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Decreased expression and andro ...... ene INPP4B in prostate cancer.

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Decreased expression and andro ...... ene INPP4B in prostate cancer.

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0008-5472.CAN-10-2314

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Cancer Research

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Decreased expression and andro ...... gene INPP4B in prostate cancer

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Anna Frolov

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Gustavo Ayala

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Long-jiang Shao

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Michael M Ittmann

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Myles C Hodgson

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Nancy L Weigel

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Rile Li

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P2860

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Androgen-induced proliferative quiescence in prostate cancer cells: the role of AS3 as its mediator

Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

Expression of novel genes linked to the androgen-induced, proliferative shutoff in prostate cancer cells

Involvement of arginine methyltransferase CARM1 in androgen receptor function and prostate cancer cell viability

A genetic screen for candidate tumor suppressors identifies REST

Regulation of androgen receptor signaling by PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor through distinct mechanisms in prostate cancer cells

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Pten is essential for embryonic development and tumour suppression

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Leif E. Peterson

Irina U. Agoulnik

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2011-01-11T00:00:00Z

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21224358

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