Evaluation of anti-podoplanin rat monoclonal antibody NZ-1 for targeting malignant gliomas - Wikidata - awgldk - TriplyDB

Evaluation of anti-podoplanin rat monoclonal antibody NZ-1 for targeting malignant gliomas

Evaluation of anti-podoplanin rat monoclonal antibody NZ-1 for targeting malignant gliomas

http://www.wikidata.org/entity/Q34160649

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Toxin-based targeted therapy for malignant brain tumors A cancer-specific monoclonal antibody recognizes the aberrantly glycosylated podoplanin.LpMab-12 Established by CasMab Technology Specifically Detects Sialylated O-Glycan on Thr52 of Platelet Aggregation-Stimulating Domain of Human Podoplanin.PKA and CDK5 can phosphorylate specific serines on the intracellular domain of podoplanin (PDPN) to inhibit cell motility Plant lectin can target receptors containing sialic acid, exemplified by podoplanin, to inhibit transformed cell growth and migration.SIB-DOTA: a trifunctional prosthetic group potentially amenable for multi-modal labeling that enhances tumor uptake of internalizing monoclonal antibodies The chimeric antibody chLpMab-7 targeting human podoplanin suppresses pulmonary metastasis via ADCC and CDC rather than via its neutralizing activity.Identification of a novel platelet antagonist that binds to CLEC-2 and suppresses podoplanin-induced platelet aggregation and cancer metastasis Serines in the intracellular tail of podoplanin (PDPN) regulate cell motility.Recombinant anti-podoplanin (NZ-1) immunotoxin for the treatment of malignant brain tumors.Development and characterization of anti-glycopeptide monoclonal antibodies against human podoplanin, using glycan-deficient cell lines generated by CRISPR/Cas9 and TALEN.Radioimmunotherapy for high-grade glioma.Antibody-drug conjugates in glioblastoma therapy: the right drugs to the right cells.Development and validation of a cell-based fluorescent method for measuring antibody affinity.Antitumor effect of novel anti-podoplanin antibody NZ-12 against malignant pleural mesothelioma in an orthotopic xenograft model.Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms.Characterization of monoclonal antibody LpMab-3 recognizing sialylated glycopeptide of podoplanin.Podoplanin: a marker for reactive gliosis in gliomas and brain injury.Podoplanin Expression in Canine Melanoma.Recombinant Immunotoxin Therapy of Glioblastoma: Smart Design, Key Findings, and Specific Challenges.Development of RAP Tag, a Novel Tagging System for Protein Detection and Purification.Antitumor activity of chLpMab-2, a human-mouse chimeric cancer-specific antihuman podoplanin antibody, via antibody-dependent cellular cytotoxicity.Selection of novel affinity-matured human chondroitin sulfate proteoglycan 4 antibody fragments by yeast display.

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Evaluation of anti-podoplanin rat monoclonal antibody NZ-1 for targeting malignant gliomas

http://www.wikidata.org/entity/Q34160649

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Evaluation of anti-podoplanin ...... or targeting malignant gliomas

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Evaluation of anti-podoplanin ...... or targeting malignant gliomas

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Evaluation of anti-podoplanin ...... or targeting malignant gliomas

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Evaluation of anti-podoplanin ...... or targeting malignant gliomas

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Evaluation of anti-podoplanin ...... or targeting malignant gliomas

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Evaluation of anti-podoplanin ...... or targeting malignant gliomas

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Evaluation of anti-podoplanin ...... or targeting malignant gliomas

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Evaluation of anti-podoplanin ...... or targeting malignant gliomas

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J.NUCMEDBIO.2010.03.010

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Nuclear Medicine and Biology

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Evaluation of anti-podoplanin ...... or targeting malignant gliomas

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Charles Pegram

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Chien-Tsun Kuan

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Ganesan Vaidyanathan

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Kazuhiko Mishima

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Michael R Zalutsky

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Mika Kato Kaneko

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Nidhi Srivastava

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Stephen T Keir

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Vidyalakshmi Chandramohan

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Yukinari Kato

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P2860

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Identification of human brain tumour initiating cells

Molecular identification of Aggrus/T1alpha as a platelet aggregation-inducing factor expressed in colorectal tumors

The platelet aggregation-inducing factor aggrus/podoplanin promotes pulmonary metastasis

Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton

Podoplanin expression in primary central nervous system germ cell tumors: a useful histological marker for the diagnosis of germinoma

Functional sialylated O-glycan to platelet aggregation on Aggrus (T1alpha/Podoplanin) molecules expressed in Chinese hamster ovary cells

Characterization of human PA2.26 antigen (T1alpha-2, podoplanin), a small membrane mucin induced in oral squamous cell carcinomas

Low podoplanin expression in pretreatment biopsy material predicts poor prognosis in advanced-stage squamous cell carcinoma of the uterine cervix treated by primary radiation

Increased expression of podoplanin in malignant astrocytic tumors as a novel molecular marker of malignant progression

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785-794

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10.1016/J.NUCMEDBIO.2010.03.010

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7

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37

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Darell D. Bigner

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46426662

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