Signal strength in thymic selection and lineage commitment.
about
A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signalingGATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiationRegulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zetaGenome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell typesFunctional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice.Low T cell receptor expression and thermal fluctuations contribute to formation of dynamic multifocal synapses in thymocytes.Distinct temporal patterns of T cell receptor signaling during positive versus negative selection in situDistinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns.Perspectives for computer modeling in the study of T cell activationTCR affinity for self-ligands influences the development and function of encephalitogenic T cells.A requirement for sustained ERK signaling during thymocyte positive selection in vivo.Critical role of TCF-1 in repression of the IL-17 gene.Genetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression.Development of thymically derived natural regulatory T cells.Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes.Life and death in the thymus--cell death signaling during T cell development.Lymphostromal interactions in thymic development and function.Optimal T-cell receptor affinity for inducing autoimmunity.A conformational change senses the strength of T cell receptor-ligand interaction during thymic selection.Known and potential functions for the SLP-76 adapter protein in regulating T-cell activation and development.The NF-κB1 transcription factor prevents the intrathymic development of CD8 T cells with memory propertiesBcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation.Involvement of the TCR Cbeta FG loop in thymic selection and T cell function.The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit+ T cell progenitors and CD4/CD8 lineage decision in the thymusStrength of signal: a fundamental mechanism for cell fate specification.Recent insights into the signals that control alphabeta/gammadelta-lineage fate.The CD8 population in CD4-deficient mice is heavily contaminated with MHC class II-restricted T cells.Phosphorylation of histone deacetylase 7 by protein kinase D mediates T cell receptor-induced Nur77 expression and apoptosis.The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells.c-Rel: shaping CD4 regulatory T cell development in unexpected ways.Differential role of the transcription factor NF-kappaB in selection and survival of CD4+ and CD8+ thymocytes.SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway.Vitamin C promotes maturation of T-cells.Cutting Edge: Ikaros null thymocytes mature into the CD4 lineage with reduced TCR signal: A study using CD3{zeta} immunoreceptor tyrosine-based activation motif transgenic mice.SAP-Dependent and -Independent Regulation of Innate T Cell Development Involving SLAMF Receptors.Apoptosis and autophagy: decoding calcium signals that mediate life or death.T-cell receptor retrogenic mice: a rapid, flexible alternative to T-cell receptor transgenic mice.NF-κB subunit specificity in hemopoiesis.Bcl-2 regulation of the inositol 1,4,5-trisphosphate receptor and calcium signaling in normal and malignant lymphocytes: potential new target for cancer treatment.T Cell's Sense of Self: a Role of Self-Recognition in Shaping Functional Competence of Naïve T Cells.
P2860
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P2860
Signal strength in thymic selection and lineage commitment.
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Signal strength in thymic selection and lineage commitment.
@ast
Signal strength in thymic selection and lineage commitment.
@en
Signal strength in thymic selection and lineage commitment.
@nl
type
label
Signal strength in thymic selection and lineage commitment.
@ast
Signal strength in thymic selection and lineage commitment.
@en
Signal strength in thymic selection and lineage commitment.
@nl
prefLabel
Signal strength in thymic selection and lineage commitment.
@ast
Signal strength in thymic selection and lineage commitment.
@en
Signal strength in thymic selection and lineage commitment.
@nl
P1476
Signal strength in thymic selection and lineage commitment
@en
P2093
Hogquist KA
P304
P356
10.1016/S0952-7915(00)00208-9
P577
2001-04-01T00:00:00Z