miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells.
about
Clinical significance of microRNAs in chronic and acute human leukemiaMicroRNAs in B-cell lymphomas: how a complex biology gets more complexLF-MF inhibits iron metabolism and suppresses lung cancer through activation of P53-miR-34a-E2F1/E2F3 pathway.MDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer.Posttranscriptional deregulation of Src due to aberrant miR34a and miR203 contributes to gastric cancer developmentSodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3.Targeting the Warburg effect with a novel glucose transporter inhibitor to overcome gemcitabine resistance in pancreatic cancer cells.The p53 transcriptional pathway is preserved in ATMmutated and NOTCH1mutated chronic lymphocytic leukemias.The anti-leukemic activity of sodium dichloroacetate in p53mutated/null cells is mediated by a p53-independent ILF3/p21 pathwayMiR-34a suppresses amphiregulin and tumor metastatic potential of head and neck squamous cell carcinoma (HNSCC)p53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Integrated Pulsed Stable Isotope Labeling With Amino Acids in Cell Culture (pSILAC) and Next Generation Sequencing (NGS) AnalysesLincHOTAIR epigenetically silences miR34a by binding to PRC2 to promote the epithelial-to-mesenchymal transition in human gastric cancerMicroRNAs in Acute Myeloid Leukemia and Other Blood Disorders.MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid MalignanciesThe miR-34a-LDHA axis regulates glucose metabolism and tumor growth in breast cancerIbrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia.rs35301225 polymorphism in miR-34a promotes development of human colon cancer by deregulation of 3'UTR in E2F1 in Chinese population.MYBL2 (B-Myb): a central regulator of cell proliferation, cell survival and differentiation involved in tumorigenesis.Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1.Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia.Upregulation of SOCS-1 by Nutlin-3 in acute myeloid leukemia cells but not in primary normal cells.MiRNA-329 targeting E2F1 inhibits cell proliferation in glioma cells.Proper design of silica nanoparticles combines high brightness, lack of cytotoxicity and efficient cell endocytosis.Selective induction of TP53I3/p53-inducible gene 3 (PIG3) in myeloid leukemic cells, but not in normal cells, by Nutlin-3.MiR-34a inhibits proliferation and migration of breast cancer through down-regulation of Bcl-2 and SIRT1.Transcriptome-wide characterization of the endogenous miR-34A-p53 tumor suppressor networkComparative miRNA Expression Profile Analysis of Squamous Cell Carcinoma and Peritumoral Mucosa from the Meso- and Hypopharynx.The non-genotoxic activator of the p53 pathway Nutlin-3 shifts the balance between E2F7 and E2F1 transcription factors in leukemic cells.miR-34a increases cisplatin sensitivity of osteosarcoma cells in vitro through up-regulation of c-Myc and Bim signal.
P2860
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P2860
miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells.
@ast
miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells.
@en
miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells.
@nl
type
label
miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells.
@ast
miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells.
@en
miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells.
@nl
prefLabel
miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells.
@ast
miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells.
@en
miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells.
@nl
P2093
P1476
miR-34a induces the downregulation of both E2F1 and B-Myb oncogenes in leukemic cells.
@en
P2093
Elisabetta Melloni
Maria Elena Sana
Maria Grazia di Iasio
Raffaella Bosco
Rebecca Voltan
P304
P356
10.1158/1078-0432.CCR-10-3244
P407
P577
2011-03-02T00:00:00Z