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Analysis of variation at transcription factor binding sites in Drosophila and humansSynthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactionsDerivation of genetic interaction networks from quantitative phenotype dataNetwork hubs buffer environmental variation in Saccharomyces cerevisiaeGenotype to phenotype: a complex problem'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?Epistasis--the essential role of gene interactions in the structure and evolution of genetic systemsComplexity of type 2 diabetes mellitus data sets emerging from nutrigenomic research: a case for dimensionality reduction?Dissection of epistasis in oligogenic Bardet-Biedl syndromeGenetic analysis of yeast Yip1p function reveals a requirement for Golgi-localized rab proteins and rab-Guanine nucleotide dissociation inhibitorTFIID and Spt-Ada-Gcn5-acetyltransferase functions probed by genome-wide synthetic genetic array analysis using a Saccharomyces cerevisiae taf9-ts alleleA microRNA imparts robustness against environmental fluctuation during developmentSystematic quantification of gene interactions by phenotypic array analysisCommensurate distances and similar motifs in genetic congruence and protein interaction networks in yeastLarge-scale 13C-flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeastPolymorphisms of the Flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in CaucasiansStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewFine tuning chemotherapy to match BRCA1 statusChemical-genetic profile analysis of five inhibitory compounds in yeast.A yeast phenomic model for the gene interaction network modulating CFTR-ΔF508 protein biogenesis.Avl9p, a member of a novel protein superfamily, functions in the late secretory pathway.Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast.The ATP-dependent chromatin remodeling enzyme Fun30 represses transcription by sliding promoter-proximal nucleosomes.Annotating novel genes by integrating synthetic lethals and genomic information.Ltv1 is required for efficient nuclear export of the ribosomal small subunit in Saccharomyces cerevisiaePosttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks.Yeast Pak1 kinase associates with and activates Snf1Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway.Transcriptome profiling to identify genes involved in peroxisome assembly and functionUse of poly ADP-ribose polymerase [PARP] inhibitors in cancer cells bearing DDR defects: the rationale for their inclusion in the clinicPrediction of Genetic Interactions Using Machine Learning and Network PropertiesThe Aspergillus nidulans musN gene encodes a RecQ helicase that interacts with the PI-3K-related kinase UVSBInformation flow analysis of interactome networksSynergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazoleAncestral genes can control the ability of horizontally acquired loci to confer new traitsAdaptation of the myoglobin knockout mouse to hypoxic stressASDCD: antifungal synergistic drug combination databaseThe causal effect of vitamin D binding protein (DBP) levels on calcemic and cardiometabolic diseases: a Mendelian randomization studyPredicting human genetic interactions from cancer genome evolutionRibosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Principles for the buffering of genetic variation.
@ast
Principles for the buffering of genetic variation.
@en
Principles for the buffering of genetic variation.
@nl
type
label
Principles for the buffering of genetic variation.
@ast
Principles for the buffering of genetic variation.
@en
Principles for the buffering of genetic variation.
@nl
altLabel
Principles for the Buffering of Genetic Variation
@en
Principles for the buffering of genetic variation
@en
prefLabel
Principles for the buffering of genetic variation.
@ast
Principles for the buffering of genetic variation.
@en
Principles for the buffering of genetic variation.
@nl
P2093
P1433
P1476
Principles for the buffering of genetic variation.
@en
P2093
Hartman JL 4th
Hartwell L
P304
P356
10.1126/SCIENCE.291.5506.1001
P407
P577
2001-02-01T00:00:00Z