Mammalian genes are transcribed with widely different bursting kinetics.
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PML promotes MHC class II gene expression by stabilizing the class II transactivatorGene switching rate determines response to extrinsic perturbations in the self-activation transcriptional network motifSingle-cell transcriptome sequencing: recent advances and remaining challengesMathematical models light up plant signalingGenetic determinants and cellular constraints in noisy gene expressionThe prolactin gene: a paradigm of tissue-specific gene regulation with complex temporal transcription dynamicsUsing variability in gene expression as a tool for studying gene regulationTranscription goes digitalApproaches to engineer stability of beetle luciferasesMolecular architecture of the mammalian circadian clockProtein expression analyses at the single cell levelA continuum model of transcriptional bursting.Rapid transcriptional pulsing dynamics of high expressing retroviral transgenes in embryonic stem cellsPersistent cell-autonomous circadian oscillations in fibroblasts revealed by six-week single-cell imaging of PER2::LUC bioluminescenceSingle mammalian cells compensate for differences in cellular volume and DNA copy number through independent global transcriptional mechanisms.High-throughput analysis of NF-κB dynamics in single cells reveals basal nuclear localization of NF-κB and spontaneous activation of oscillationsReal-time quantification of protein expression at the single-cell level via dynamic protein synthesis translocation reporters.Unbiased identification of signal-activated transcription factors by barcoded synthetic tandem repeat promoter screening (BC-STAR-PROM)Clk post-transcriptional control denoises circadian transcription both temporally and spatially.New methods to image transcription in living fly embryos: the insights so far, and the prospectsQuantitative imaging of mammalian transcriptional dynamics: from single cells to whole embryosFrom Structural Variation of Gene Molecules to Chromatin Dynamics and Transcriptional BurstingEstimation and discrimination of stochastic biochemical circuits from time-lapse microscopy datalinc-HOXA1 is a noncoding RNA that represses Hoxa1 transcription in cisA computational framework for analyzing stochasticity in gene expressionEffects of cell-cycle-dependent expression on random fluctuations in protein levelsRNA synthesis is associated with multiple TBP-chromatin binding eventsRNA-sequencing from single nuclei.Measuring chromatin interaction dynamics on the second time scale at single-copy genes.Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome.Functional optoacoustic human angiography with handheld video rate three dimensional scannerQuantitative assessment of ratiometric bimolecular beacons as a tool for imaging single engineered RNA transcripts and measuring gene expression in living cells.Patch-clamp recordings and calcium imaging followed by single-cell PCR reveal the developmental profile of 13 genes in iPSC-derived human neurons.Mechanism of transcriptional bursting in bacteria.Universal dynamical properties preclude standard clustering in a large class of biochemical data.Tracing the molecular basis of transcriptional dynamics in noisy data by using an experiment-based mathematical model.A stochastic transcriptional switch model for single cell imaging data.Determining Physical Mechanisms of Gene Expression Regulation from Single Cell Gene Expression DataTranscriptional regulation of lineage commitment--a stochastic model of cell fate decisions.Robustness of DNA repair through collective rate control.
P2860
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P2860
Mammalian genes are transcribed with widely different bursting kinetics.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
Mammalian genes are transcribed with widely different bursting kinetics.
@ast
Mammalian genes are transcribed with widely different bursting kinetics.
@en
Mammalian genes are transcribed with widely different bursting kinetics.
@nl
type
label
Mammalian genes are transcribed with widely different bursting kinetics.
@ast
Mammalian genes are transcribed with widely different bursting kinetics.
@en
Mammalian genes are transcribed with widely different bursting kinetics.
@nl
prefLabel
Mammalian genes are transcribed with widely different bursting kinetics.
@ast
Mammalian genes are transcribed with widely different bursting kinetics.
@en
Mammalian genes are transcribed with widely different bursting kinetics.
@nl
P2093
P2860
P356
P1433
P1476
Mammalian genes are transcribed with widely different bursting kinetics.
@en
P2093
David Gatfield
Felix Naef
Kim Schneider
Nacho Molina
P2860
P304
P356
10.1126/SCIENCE.1198817
P407
P577
2011-03-17T00:00:00Z