Insights into the biosynthesis of hormaomycin, an exceptionally complex bacterial signaling metabolite.
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Crystal structure of a member of a novel family of dioxygenases (PF10014) reveals a conserved cupin fold and active siteUnusual N-prenylation in diazepinomicin biosynthesis: the farnesylation of a benzodiazepine substrate is catalyzed by a new member of the ABBA prenyltransferase superfamilyAdaptation of an L-proline adenylation domain to use 4-propyl-L-proline in the evolution of lincosamide biosynthesisBiosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pairAn environmental bacterial taxon with a large and distinct metabolic repertoire.Identification of the dioxygenase-generated intermediate formed during biosynthesis of the dihydropyrrole moiety common to anthramycin and sibiromycinLincomycin biosynthesis involves a tyrosine hydroxylating heme protein of an unusual enzyme family.Lincosamide synthetase--a unique condensation system combining elements of nonribosomal peptide synthetase and mycothiol metabolism.Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.Nonproteinogenic amino acid building blocks for nonribosomal peptide and hybrid polyketide scaffolds.Nonribosomal Peptide Synthesis-Principles and Prospects.Molecular regulation of antibiotic biosynthesis in streptomyces.Structure and noncanonical chemistry of nonribosomal peptide biosynthetic machinery.A heme peroxidase with a functional role as an L-tyrosine hydroxylase in the biosynthesis of anthramycin.Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.New Concept of the Biosynthesis of 4-Alkyl-L-Proline Precursors of Lincomycin, Hormaomycin, and Pyrrolobenzodiazepines: Could a γ-Glutamyltransferase Cleave the C-C Bond?Biosynthetic engineering of nonribosomal peptide synthetases.Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.Co-overexpression of lmbW and metK led to increased lincomycin A production and decreased byproduct lincomycin B content in an industrial strain of Streptomyces lincolnensis.4-alkyl-L-(Dehydro)proline biosynthesis in actinobacteria involves N-terminal nucleophile-hydrolase activity of γ-glutamyltranspeptidase homolog for C-C bond cleavageAn Activator of an Adenylation Domain Revealed by Activity but Not Sequence Homology.The novel transcriptional regulator LmbU promotes lincomycin biosynthesis through regulating expression of its target genes in Streptomyces lincolnensis.Evolution-guided adaptation of an adenylation domain substrate specificity to an unusual amino acid.Reprogramming the Biosynthesis of Cyclodepsipeptide Synthetases to Obtain New Enniatins and Beauvericins.Production of Antimicrobial Compounds by Fermentation.Novel pathway of 3-hydroxyanthranilic acid formation in limazepine biosynthesis reveals evolutionary relation between phenazines and pyrrolobenzodiazepines.C-C bond cleavage in biosynthesis of 4-alkyl-L-proline precursors of lincomycin and anthramycin cannot precede C-methylation
P2860
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P2860
Insights into the biosynthesis of hormaomycin, an exceptionally complex bacterial signaling metabolite.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Insights into the biosynthesis ...... acterial signaling metabolite.
@ast
Insights into the biosynthesis ...... acterial signaling metabolite.
@en
Insights into the biosynthesis ...... acterial signaling metabolite.
@nl
type
label
Insights into the biosynthesis ...... acterial signaling metabolite.
@ast
Insights into the biosynthesis ...... acterial signaling metabolite.
@en
Insights into the biosynthesis ...... acterial signaling metabolite.
@nl
prefLabel
Insights into the biosynthesis ...... acterial signaling metabolite.
@ast
Insights into the biosynthesis ...... acterial signaling metabolite.
@en
Insights into the biosynthesis ...... acterial signaling metabolite.
@nl
P2093
P1476
Insights into the biosynthesis ...... bacterial signaling metabolite
@en
P2093
Axel Zeeck
Bernadette Geers
Daniel Flachshaar
Ivonne Höfer
Markus Radzom
Xiaofeng Cai
P304
P356
10.1016/J.CHEMBIOL.2010.12.018
P577
2011-03-01T00:00:00Z