about
Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastomaSmall-molecule inhibitors of the Myc oncoproteinMYC activation is a hallmark of cancer initiation and maintenanceOmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumorsTherapeutic aspects of c-MYC signaling in inflammatory and cancerous colonic diseasesDrugging the addict: non-oncogene addiction as a target for cancer therapyInhibitor of MYC identified in a Kröhnke pyridine libraryMYC on the path to cancerInactivation of MYC reverses tumorigenesis.The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy.Exploiting biological diversity and genomic aberrations in chronic lymphocytic leukemia.Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis.The Max b-HLH-LZ can transduce into cells and inhibit c-Myc transcriptional activities.Cancer. Taking a back door to target Myc.A cell engineering strategy to enhance the safety of stem cell therapies.Transcriptional amplification in tumor cells with elevated c-Myc.Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft modelThe bromodomain and extra-terminal inhibitor CPI203 enhances the antiproliferative effects of rapamycin on human neuroendocrine tumors.Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia.Finding cancer's weakest link.Genomics in 2011: challenges and opportunities.Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells.Deciphering the Key Features of Malignant Tumor Microenvironment for Anti-cancer TherapyStrategies to Inhibit Myc and Their Clinical ApplicabilityRole of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma.Inhibition of Myc family proteins eradicates KRas-driven lung cancer in miceNoncanonical roles of the immune system in eliciting oncogene addictionCombined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinomaGrowth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation.Multiple Roles of MYC in Integrating Regulatory Networks of Pluripotent Stem Cells.Andrographolide suppress tumor growth by inhibiting TLR4/NF-κB signaling activation in insulinomaNatriuretic peptide receptor A signaling regulates stem cell recruitment and angiogenesis: a model to study linkage between inflammation and tumorigenesis.The chemokine system and cancer.Tumor microenvironment: becoming sick of Myc.Immunology in the clinic review series; focus on cancer: multiple roles for the immune system in oncogene addiction.The impact of tumor microenvironment on cancer treatment and its modulation by direct and indirect antivascular strategies.MYC oncogene in myeloid neoplasias.MYC-y mice: from tumour initiation to therapeutic targeting of endogenous MYC.The fine balance of chemokines during disease: trafficking, inflammation, and homeostasis.The accumulation of DNA repair defects is the molecular origin of carcinogenesis.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Endogenous Myc maintains the tumor microenvironment.
@ast
Endogenous Myc maintains the tumor microenvironment.
@en
Endogenous Myc maintains the tumor microenvironment.
@nl
type
label
Endogenous Myc maintains the tumor microenvironment.
@ast
Endogenous Myc maintains the tumor microenvironment.
@en
Endogenous Myc maintains the tumor microenvironment.
@nl
prefLabel
Endogenous Myc maintains the tumor microenvironment.
@ast
Endogenous Myc maintains the tumor microenvironment.
@en
Endogenous Myc maintains the tumor microenvironment.
@nl
P2093
P2860
P356
P1433
P1476
Endogenous Myc maintains the tumor microenvironment.
@en
P2093
Anthony N Karnezis
Douglas Hanahan
Gerard I Evan
Lamorna Brown Swigart
Nicole M Sodir
P2860
P304
P356
10.1101/GAD.2038411
P50
P577
2011-04-08T00:00:00Z