Selectin-like kinetics and biomechanics promote rapid platelet adhesion in flow: the GPIb(alpha)-vWF tether bond.
about
Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutationsCatch bonds govern adhesion through L-selectin at threshold shearThe platelet and the biophysical microenvironment: lessons from cellular mechanicsMultiscale systems biology and physics of thrombosis under flow.In microfluidico: Recreating in vivo hemodynamics using miniaturized devicesFunctional analysis of the combined role of the O-linked branching enzyme core 2 beta1-6-N-glucosaminyltransferase and dimerization of P-selectin glycoprotein ligand-1 in rolling on P-selectinRegulation of L-selectin-dependent hydrodynamic shear thresholding by leukocyte deformability and shear dependent bond number.L-selectin shear thresholding modulates leukocyte secondary capture.Catch-bond model derived from allostery explains force-activated bacterial adhesion.Neutrophil-bead collision assay: pharmacologically induced changes in membrane mechanics regulate the PSGL-1/P-selectin adhesion lifetime.Neutrophil string formation: hydrodynamic thresholding and cellular deformation during cell collisions.Activation-independent platelet adhesion and aggregation under elevated shear stressPlatelet glycoprotein Ibalpha forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF.Shear-enhanced oral microbial adhesion.Multiscale prediction of patient-specific platelet function under flowPlatelet adhesion involves a novel interaction between vimentin and von Willebrand factor under high shear stressL-selectin-mediated leukocyte tethering in shear flow is controlled by multiple contacts and cytoskeletal anchorage facilitating fast rebinding eventsFimH forms catch bonds that are enhanced by mechanical force due to allosteric regulation.Humanized mouse model of thrombosis is predictive of the clinical efficacy of antiplatelet agents.Three-dimensional multi-scale model of deformable platelets adhesion to vessel wall in blood flow.Effect of Red Blood Cells on Platelet Activation and Thrombus Formation in Tortuous ArteriolesThe mechanism of VWF-mediated platelet GPIbalpha binding.A selective microRNA-based strategy inhibits restenosis while preserving endothelial function.Kinetics of GPIbalpha-vWF-A1 tether bond under flow: effect of GPIbalpha mutations on the association and dissociation rates.Mechanics of transient platelet adhesion to von Willebrand factor under flowvon Willebrand factor self-association on platelet GpIbalpha under hydrodynamic shear: effect on shear-induced platelet activationGPIbα-vWF rolling under shear stress shows differences between type 2B and 2M von Willebrand disease.Platelet adhesion from shear blood flow is controlled by near-wall rebounding collisions with erythrocytesTwo-dimensional kinetics regulation of alphaLbeta2-ICAM-1 interaction by conformational changes of the alphaL-inserted domainPlatelet adhesion under flow.Exploiting the kinetic interplay between GPIbα-VWF binding interfaces to regulate hemostasis and thrombosisSimulation of platelet, thrombus and erythrocyte hydrodynamic interactions in a 3D arteriole with in vivo comparisonMatrix protein microarrays for spatially and compositionally controlled microspot thrombosis under laminar flow.Transport regulation of two-dimensional receptor-ligand associationEffect of loading conditions on the dissociation behaviour of catch bond clusters.Inactive conformation enhances binding function in physiological conditionsTargeting shear stress-induced platelet activation: is lesion-specific antiplatelet therapy a realistic clinical goal?The role of fibrinogen spacing and patch size on platelet adhesion under flow.Avidity enhancement of L-selectin bonds by flow: shear-promoted rotation of leukocytes turn labile bonds into functional tethers.Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress.
P2860
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P2860
Selectin-like kinetics and biomechanics promote rapid platelet adhesion in flow: the GPIb(alpha)-vWF tether bond.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Selectin-like kinetics and biomechanics promote rapid platelet adhesion in flow: the GPIb
@nl
Selectin-like kinetics and bio ...... e GPIb(alpha)-vWF tether bond.
@ast
Selectin-like kinetics and bio ...... e GPIb(alpha)-vWF tether bond.
@en
type
label
Selectin-like kinetics and biomechanics promote rapid platelet adhesion in flow: the GPIb
@nl
Selectin-like kinetics and bio ...... e GPIb(alpha)-vWF tether bond.
@ast
Selectin-like kinetics and bio ...... e GPIb(alpha)-vWF tether bond.
@en
prefLabel
Selectin-like kinetics and biomechanics promote rapid platelet adhesion in flow: the GPIb
@nl
Selectin-like kinetics and bio ...... e GPIb(alpha)-vWF tether bond.
@ast
Selectin-like kinetics and bio ...... e GPIb(alpha)-vWF tether bond.
@en
P2093
P2860
P1433
P1476
Selectin-like kinetics and bio ...... e GPIb(alpha)-vWF tether bond.
@en
P2093
Avril Lawshé
David W Schmidtke
Gaurav Girdhar
Ian J Laurenzi
Scott L Diamond
Teresa A Doggett
Thomas G Diacovo
P2860
P304
P356
10.1016/S0006-3495(02)75161-8
P407
P577
2002-07-01T00:00:00Z