RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells
about
Y-box-binding protein 1 interacts with hepatitis C virus NS3/4A and influences the equilibrium between viral RNA replication and infectious particle productionTowards in vivo application of RNA interference - new toys, old problemsActively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA.Prospects for nucleic acid-based therapeutics against hepatitis C virusCombinations of siRNAs against La Autoantigen with NS5B or hVAP-A Have Additive Effect on Inhibition of HCV ReplicationHepatitis C Virus Replicons Escape RNA Interference Induced by a Short Interfering RNA Directed against the NS5b Coding RegionEffect of cell growth on hepatitis C virus (HCV) replication and a mechanism of cell confluence-based inhibition of HCV RNA and protein expressionSmall interfering RNA targeted to stem-loop II of the 5' untranslated region effectively inhibits expression of six HCV genotypesSmall Interfering RNA Targeted to Hepatitis C Virus 5' Nontranslated Region Exerts Potent Antiviral EffectNew pandemics: HIV and AIDS, HCV and chronic hepatitis, influenza virus and fluSuppression Of Hepatitis C Virus Core Protein By Short Hairpin Rna Expression Vectors In The Core Protein Expression Huh-7 CellsHarnessing the RNA interference pathway to advance treatment and prevention of hepatocellular carcinomaCombined antiviral activity of interferon-α and RNA interference directed against hepatitis C without affecting vector delivery and gene silencingRefractoriness of hepatitis C virus internal ribosome entry site to processing by Dicer in vivoInhibition of west nile virus replication by retrovirus-delivered small interfering RNA in human neuroblastoma cellsInvestigating a New Generation of Ribozymes in Order to Target HCVsiRNAs: potential therapeutic agents against hepatitis C virusBioluminescence imaging allows monitoring hepatitis C virus core protein inhibitors in miceExploring the functions of RNA interference pathway proteins: some functions are more RISCy than others?In silico target-specific siRNA design based on domain transfer in heterogeneous data.High-throughput RNAi screening in vitro: from cell lines to primary cells.Oligonucleotide-based knockdown technologies: antisense versus RNA interference.Short interfering RNA (siRNA) as a novel therapeutic.Synthetic small interfering RNA targeting heat shock protein 105 induces apoptosis of various cancer cells both in vitro and in vivo.Hepatitis B virus inhibition in mice by lentiviral vector mediated short hairpin RNA.Minimal-length Synthetic shRNAs Formulated with Lipid Nanoparticles are Potent Inhibitors of Hepatitis C Virus IRES-linked Gene Expression in MiceInhibition of coxsackievirus B3 replication by small interfering RNAs requires perfect sequence match in the central region of the viral positive strand.In vitro inhibition of porcine hemagglutinating encephalomyelitis virus replication with siRNAs targeting the spike glycoprotein and replicase polyprotein genes.Self-assembled lipid nanomedicines for siRNA tumor targeting.Activity-based protein profiling identifies a host enzyme, carboxylesterase 1, which is differentially active during hepatitis C virus replication.Human Ago2 is required for efficient microRNA 122 regulation of hepatitis C virus RNA accumulation and translation.Unlocking the potential of the human genome with RNA interference.The FHA domain protein SNIP1 is a regulator of the cell cycle and cyclin D1 expression.Inhibition of core gene of HCV 3a genotype using synthetic and vector derived siRNAssiRNA therapeutics: big potential from small RNAs.Antiviral effects of human immunodeficiency virus type 1-specific small interfering RNAs against targets conserved in select neurotropic viral strains.RNAi therapeutics: principles, prospects and challenges.Post-transcriptional inhibition of hepatitis C virus replication through small interference RNA.Inhibition of full length hepatitis C virus particles of 1a genotype through small interference RNATransient replication of Hepatitis C Virus sub-genomic RNA in murine cell lines is enabled by miR-122 and varies with cell passage
P2860
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P2860
RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
RNA interference blocks gene e ...... ropagated in human liver cells
@ast
RNA interference blocks gene e ...... ropagated in human liver cells
@en
RNA interference blocks gene e ...... ropagated in human liver cells
@nl
type
label
RNA interference blocks gene e ...... ropagated in human liver cells
@ast
RNA interference blocks gene e ...... ropagated in human liver cells
@en
RNA interference blocks gene e ...... ropagated in human liver cells
@nl
prefLabel
RNA interference blocks gene e ...... ropagated in human liver cells
@ast
RNA interference blocks gene e ...... ropagated in human liver cells
@en
RNA interference blocks gene e ...... ropagated in human liver cells
@nl
P2093
P2860
P356
P1476
RNA interference blocks gene e ...... ropagated in human liver cells
@en
P2093
Anastasia Khvorova
Christopher D Richardson
Farida Sarangi
Ian Gaël Rodrigue-Gervais
Joyce A Wilson
Marees Harris-Brandts
Sarah Sabatinos
Sudha Arya
Sumedha Jayasena
Sylvie Beaulieu
P2860
P304
P356
10.1073/PNAS.252758799
P407
P577
2003-02-19T00:00:00Z