Selective stabilization of the chorismate mutase transition state by a positively charged hydrogen bond donor.
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pH Dependence of Catalysis by Pseudomonas aeruginosa Isochorismate–Pyruvate Lyase: Implications for Transition State Stabilization and the Role of Lysine 42Semisynthetic Nanoreactor for Reversible Single-Molecule Covalent ChemistryElectrostatic transition state stabilization rather than reactant destabilization provides the chemical basis for efficient chorismate mutase catalysis.Mechanistic insights into the isochorismate pyruvate lyase activity of the catalytically promiscuous PchB from combinatorial mutagenesis and selection.Toward accurate screening in computer-aided enzyme design.Transition-state charge stabilization through multiple non-covalent interactions in the guanidinium-catalyzed enantioselective Claisen rearrangementThe proficiency of a thermophilic chorismate mutase enzyme is solely through an entropic advantage in the enzyme reaction.The near attack conformation approach to the study of the chorismate to prephenate reaction.Pericyclic reactions catalyzed by chorismate-utilizing enzymes.Deciphering enzymes. Genetic selection as a probe of structure and mechanism.Mechanisms and free energies of enzymatic reactions.Chiral N-Heterocyclic Carbene Catalyzed Annulations of Enals and Ynals with Stable Enols: A Highly Enantioselective Coates-Claisen Rearrangement.An interpretation of fluctuations in enzyme catalysis rate, spectral diffusion, and radiative component of lifetimes in terms of electric field fluctuations.How an enzyme surmounts the activation energy barrier.Preliminary X-ray crystallographic analysis of the secreted chorismate mutase from Mycobacterium tuberculosis: a tricky crystallization problem solved.The empirical valence bond as an effective strategy for computer-aided enzyme design.Mutagenesis studies of substrate recognition and catalysis in the sortase A transpeptidase from Staphylococcus aureus.Design, selection, and characterization of a split chorismate mutase.A residue outside the active site CXXC motif regulates the catalytic efficiency of Glutaredoxin 3.Quantum chemical modeling of the reaction path of chorismate mutase based on the experimental substrate/product complexIsotope effects on the enzymatic and nonenzymatic reactions of chorismate.Conformational effects in enzyme catalysis: QM/MM free energy calculation of the 'NAC' contribution in chorismate mutase.Probing protein environment in an enzymatic process: All-electron quantum chemical analysis combined with ab initio quantum mechanical/molecular mechanical modeling of chorismate mutase.Dissection of the difference between the group I metal ions in inhibiting GSK3β: a computational study.
P2860
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P2860
Selective stabilization of the chorismate mutase transition state by a positively charged hydrogen bond donor.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Selective stabilization of the ...... y charged hydrogen bond donor.
@ast
Selective stabilization of the ...... y charged hydrogen bond donor.
@en
Selective stabilization of the ...... y charged hydrogen bond donor.
@nl
type
label
Selective stabilization of the ...... y charged hydrogen bond donor.
@ast
Selective stabilization of the ...... y charged hydrogen bond donor.
@en
Selective stabilization of the ...... y charged hydrogen bond donor.
@nl
prefLabel
Selective stabilization of the ...... y charged hydrogen bond donor.
@ast
Selective stabilization of the ...... y charged hydrogen bond donor.
@en
Selective stabilization of the ...... y charged hydrogen bond donor.
@nl
P2093
P356
P1476
Selective stabilization of the ...... y charged hydrogen bond donor.
@en
P2093
Alexander Kienhöfer
Donald Hilvert
Peter Kast
P304
P356
10.1021/JA0341992
P407
P577
2003-03-01T00:00:00Z