A CAT reporter construct allows ultrasensitive estimation of TNF synthesis, and suggests that the TNF gene has been silenced in non-macrophage cell lines.
about
MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytesRequirement of two NFATc4 transactivation domains for CBP potentiationIndexing TNF-alpha gene expression using a gene-targeted reporter cell lineA reporter transgene indicates renal-specific induction of tumor necrosis factor (TNF) by shiga-like toxin. Possible involvement of TNF in hemolytic uremic syndrome.Lipid modification of the 17-kilodalton membrane immunogen of Treponema pallidum determines macrophage activation as well as amphiphilicity.The major mRNA-associated protein YB-1 is a potent 5' cap-dependent mRNA stabilizerAnalysis of tumor necrosis factor promoter responses to ultraviolet light.Polymorphism in the 3'-untranslated region of TNFalpha mRNA impairs binding of the post-transcriptional regulatory protein HuR to TNFalpha mRNA.Chromatin structure and DNase I hypersensitivity in the transcriptionally active and inactive porcine tumor necrosis factor gene locusTumor necrosis factor-alpha mediates orthopedic implant osteolysis.The tissue distribution of tumor necrosis factor biosynthesis during endotoxemiaExtinction of the tumor necrosis factor locus, and of genes encoding the lipopolysaccharide signaling pathway.IL-4-Stat6 signaling induces tristetraprolin expression and inhibits TNF-alpha production in mast cells.Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD.Constitutive activity of the tumor necrosis factor promoter is canceled by the 3' untranslated region in nonmacrophage cell lines; a trans-dominant factor overcomes this suppressive effect.Lipopolysaccharide-tumor necrosis factor-glucocorticoid interactions during cecal ligation and puncture-induced sepsis in mature versus senescent mice.Constitutive synthesis of tumor necrosis factor in the thymusNoncoding RNAs and LRRFIP1 regulate TNF expression.Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide.Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide.Characterization of the RNA binding proteins forming complexes with a novel putative regulatory region in the 3'-UTR of TNF-alpha mRNA.Mesenchymal stem cells respond to TNF but do not produce TNF.Two distinct regions in the 3' untranslated region of tumor necrosis factor alpha mRNA form complexes with macrophage proteinsEpigenetic regulation of tumor necrosis factor alpha.The immediate early genes of human cytomegalovirus upregulate tumor necrosis factor-alpha gene expression.Lipopolysaccharide and CpG DNA synergize for tumor necrosis factor-alpha production through activation of NF-kappaB.mRNA and protein stability regulate the differential expression of pro- and anti-inflammatory genes in endotoxin-tolerant THP-1 cells.Human tumor necrosis factor-alpha gene 3' untranslated region confers inducible toxin responsiveness to homologous promoter in monocytic THP-1 cells.Relative contribution of transcription and translation to the induction of tumor necrosis factor-alpha by lipopolysaccharide.Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the ras/raf-1/MEK/MAPK pathway.Silica increases tumor necrosis factor (TNF) production, in part, by upregulating the TNF promoter.Electroporation and DNA-dependent cell death in murine macrophages.Engagement of tumor necrosis factor mRNA by an endotoxin-inducible cytoplasmic protein.
P2860
Q24655976-8E9082E0-B3AA-4EEE-8E47-AB59FB555782Q28213900-AD36949D-0208-49F7-A136-E279C699B934Q33409740-D05585BD-4E98-4F26-8DB3-5C74DCE79BE3Q33493023-E5F0CAA8-D157-451D-861D-B7273C40F6E4Q33618991-2789C8C8-CE9F-4291-BF92-F39279E7FF4DQ34092756-83B78163-E95C-48E6-A546-BC252DDF5B26Q34118614-ED6BB302-1BF9-46F6-A6C8-B4733F9E5FCBQ34229483-57834D16-58AA-45F2-B3C8-D97617D2E692Q35067835-E9140B32-29BE-4CCF-920B-1EAC9E2D72DDQ35754620-6F37E6DA-4C0B-4587-91A1-22AB1683B654Q35820994-33281CB1-C53B-494A-AB8A-3F93BC92BD94Q36361659-2CAB03CC-818E-4FFF-AF9B-2C868FC1BBDDQ36371553-C6942FB1-2F0C-49CE-A003-8F39EFF2BD51Q36736233-A1CC8D4D-0984-4670-8B0E-AA5AC2DA20E5Q36793833-C4DD56E5-9511-47EB-A904-AA918AE64851Q36955855-140091F3-3983-493C-870A-25A7DFE664E4Q37032980-0DD698EA-CA32-4888-83B6-9032C403DCD7Q37662735-76190DDB-C8F6-496B-B15C-862D9098F3B3Q38306725-CDAF4061-3DA8-4B2D-846E-9C5B65EE16D5Q38318972-4E133433-86A1-4F3E-BBEB-A971FF03FA1CQ39724120-62E70350-FFDA-4315-A093-339B4AA22366Q39777508-57F193C2-A75E-4D6B-9A23-6FA5B0A2FC92Q40019999-CFFEAC29-14A4-44F1-958F-EBFE5D45731EQ40130072-FE0EC603-E6E9-475A-A621-1C4E91BAC4D9Q40334183-360CCECD-8EF4-4C49-A3EA-1B461BD78BC5Q40772877-ED1FF1E8-BFB1-42DF-B38F-BE6548D2C55CQ40886672-E7E1AA48-AC35-4B6D-9E53-722533D55656Q40939836-F74B37C9-436C-4589-A808-0A1214723A35Q41066063-EE7B023B-4709-4B0B-9D4E-9E46C6D3E9ADQ41429925-BBD88611-FC04-4428-B96E-16B80CF4BD17Q41432388-C212100A-2919-478D-9C27-DB0AEA2CDDCFQ41561238-5DB64DD1-1A85-47B4-A006-C50758CDC12AQ41941626-7104E753-906F-40C4-AEE8-DE9A9D1323A6
P2860
A CAT reporter construct allows ultrasensitive estimation of TNF synthesis, and suggests that the TNF gene has been silenced in non-macrophage cell lines.
description
1991 nî lūn-bûn
@nan
1991 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
A CAT reporter construct allow ...... in non-macrophage cell lines.
@ast
A CAT reporter construct allow ...... in non-macrophage cell lines.
@en
A CAT reporter construct allow ...... in non-macrophage cell lines.
@nl
type
label
A CAT reporter construct allow ...... in non-macrophage cell lines.
@ast
A CAT reporter construct allow ...... in non-macrophage cell lines.
@en
A CAT reporter construct allow ...... in non-macrophage cell lines.
@nl
prefLabel
A CAT reporter construct allow ...... in non-macrophage cell lines.
@ast
A CAT reporter construct allow ...... in non-macrophage cell lines.
@en
A CAT reporter construct allow ...... in non-macrophage cell lines.
@nl
P2860
P921
P356
P1476
A CAT reporter construct allow ...... in non-macrophage cell lines.
@en
P2093
P2860
P304
P356
10.1172/JCI115137
P407
P577
1991-04-01T00:00:00Z