Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter. - Wikidata - awgldk - TriplyDB

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

http://www.wikidata.org/entity/Q34184485

about

AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4 The tumor suppressor Par-4 activates an extrinsic pathway for apoptosis Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells The ZNF304-integrin axis protects against anoikis in cancer Expression and regulation of prostate apoptosis response-4 (Par-4) in human glioma stem cells in drug-induced apoptosis Par-4: a new activator of myosin phosphatase Prostate apoptosis response-4 is involved in the apoptosis response to docetaxel in MCF-7 breast cancer cells Dietary terpenoids and prostate cancer chemoprevention.Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network.Tumour-suppression activity of the proapoptotic regulator Par4.WT1 promotes cell proliferation in non-small cell lung cancer cell lines through up-regulating cyclin D1 and p-pRb in vitro and in vivo.Prostate apoptosis response 4 (Par-4), a novel substrate of caspase-3 during apoptosis activation.Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD).Role of PAR-4 in ovarian cancer.Multimolecular complex of Par-4 and E2F1 binding to Smac promoter contributes to glutamate-induced apoptosis in human- bone mesenchymal stem cells.Par-4 binds to topoisomerase 1 and attenuates its DNA relaxation activity Apoptosis and tumor resistance conferred by Par-4 Post-translational regulation of the cleaved fragment of Par-4 in ovarian and endometrial cancer cells.Par-4/THAP1 complex and Notch3 competitively regulated pre-mRNA splicing of CCAR1 and affected inversely the survival of T-cell acute lymphoblastic leukemia cells Oncoviruses and Pathogenic MicroRNAs in Humans.TRIM21 is a novel regulator of Par-4 in colon and pancreatic cancer cells The transcriptional complex between the BCL2 i-motif and hnRNP LL is a molecular switch for control of gene expression that can be modulated by small molecules.PAR-4 as a possible new target for pancreatic cancer therapy.Par-4 as a potential target for cancer therapy.PAWR-mediated suppression of BCL2 promotes switching of 3-azido withaferin A (3-AWA)-induced autophagy to apoptosis in prostate cancer cells.WT1 silencing by RNAi synergizes with chemotherapeutic agents and induces chemosensitization to doxorubicin and cisplatin in B16F10 murine melanoma cells.TMZ-induced PrPc/par-4 interaction promotes the survival of human glioma cells.Raloxifene induces cell death and inhibits proliferation through multiple signaling pathways in prostate cancer cells expressing different levels of estrogen receptor α and β.Regulation of vascular endothelial growth factor, VEGF, gene promoter by the tumor suppressor, WT1.The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.HER2/neu increases the expression of Wilms' Tumor 1 (WT1) protein to stimulate S-phase proliferation and inhibit apoptosis in breast cancer cells.Androgens repress Bcl-2 expression via activation of the retinoblastoma (RB) protein in prostate cancer cells.Exacerbation of apoptosis of cortical neurons following traumatic brain injury in par-4 transgenic mice.HtrA2, taming the oncogenic activities of WT1.Par-4 is an essential downstream target of DAP-like kinase (Dlk) in Dlk/Par-4-mediated apoptosis.Vascular endothelial growth factor (VEGF) is suppressed in WT1-transfected LNCaP cells.TNF-α and IFN-γ Together Up-Regulates Par-4 Expression and Induce Apoptosis in Human Neuroblastomas.Transcriptional regulation of pro-apoptotic Par-4 by NF-kappaB/p65 and its function in controlling cell kinetics during early events in endometrial tumourigenesis.

P2860

Q24300117-992BFC32-8812-48E7-BC26-F39DAEC92EFB Q24317521-427E3832-68F0-4F9F-968E-95698E40E491 Q24675830-2DEFCB8A-8C4F-4988-84AF-9738F64E02C1 Q24679137-8CA9ABAB-A49A-472E-9AB6-77FF28C0D135 Q28115264-D8C2446A-D078-43A6-AD29-C42B09AB8A2B Q28539708-750219D0-AC99-4A45-AAF4-359C51167DD5 Q28573207-A4C8147B-1798-40A1-83B6-0555311A2609 Q30437841-586F3A21-C45C-4429-B732-2FBF109F984E Q33606380-692A642D-E33E-4D3E-9F74-71EB45EF16CC Q33907135-33C5240E-F646-484A-AE8A-8CEA82B8BBDD Q34360323-38268DD2-5F97-4052-9CE9-DB17477FA3D2 Q34924201-675BF512-2A08-41CA-8725-52506BE75F3B Q35739198-8E7073C9-8BC4-4F18-9734-79CC0F2E41B9 Q36033271-346E907C-B6F4-4A0E-8C30-104BADDFFB5B Q36356036-468CAA64-9311-45FA-BAD4-ECFE23C6A42E Q36859241-506A7783-473E-4450-BF11-43EE9A4BE2E6 Q36926017-22C7BDFC-1E53-4BEC-8172-B6503F996B64 Q37287045-84E8A121-D222-4D8B-BAFB-8733DB883AD5 Q37392887-0841257F-5BB2-4136-9334-C8AF7C8AD741 Q37503176-64557959-EFEA-4358-8DD4-7610D230D205 Q37634314-EC60D292-95CB-4899-BA4E-FA73674BC575 Q37662004-6F7805D0-76DD-40D8-9A43-5F4CC7BFB887 Q37701002-CEEFE1D5-1D99-46CC-B6C0-A2D0EECFBC87 Q37738894-D9A94E9D-45CE-4EA2-924C-9C1A99E1F548 Q38051738-8B48181D-17FC-4FE8-ACDC-29A8BC06127C Q38895762-D8EB8ED6-3D67-487C-B5E5-D6D9F680467A Q39323696-62DCEB46-9F74-4458-9600-F7EB18D4FB8D Q39590618-6223FBCA-E42A-4F3D-BC11-61316FFB6167 Q39644350-EB05D82B-B0E0-4383-B4BB-DB5192D9FFC7 Q40204188-F520E239-59D7-44AC-BEDF-20536133EB41 Q40337569-862E10A1-67FE-45C5-AE0D-4859FF7884DF Q40464845-4F66B1CA-CA63-4203-AEE5-37A05C393DB1 Q40607145-C9221621-A5CC-45DF-AA52-118C60869428 Q40795389-492681CB-C222-404B-9268-0DB7D8BB33A7 Q42061130-113EE268-E076-4BE7-802D-7621D9A34EE9 Q42554900-A89E33DD-600B-45B9-9D45-E08230F9BD1A Q52569623-A2197EA9-732C-4725-B269-C623AF2FAB3B Q52738313-38A75EBA-7341-48A3-A010-38EE47EAD3DE Q53301550-1925AD55-AC6E-4B4E-AD57-D176EB49DC40

P2860

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

http://www.wikidata.org/entity/Q34184485

description

2003 nî lūn-bûn

@nan

2003 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի մարտին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

@ast

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

@en

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

@nl

type

label

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

@ast

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

@en

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

@nl

prefLabel

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

@ast

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

@en

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

@nl

P1433

Q34184485-26BB63D5-9A1E-426E-B787-CCEDF6EB55FA

P1476

Q34184485-B4DBA53D-AE6D-41BC-81FE-A36171CD3778

P2093

Q34184485-291E9F98-4E74-4235-B952-0E4AF0044489

Q34184485-4EA2A743-146B-400E-92ED-C44F0EAEB0C8

Q34184485-7AF20BB4-0C53-42E0-93C5-499F74797D79

Q34184485-A9ACEC29-33B5-48A3-AB1C-045003221C35

Q34184485-E0A72D30-165E-4819-A989-17AF825FDACE

Q34184485-F6FF2BCB-D273-4342-AA50-195B09424A11

P2860

Q34184485-1446384F-CEA7-45DB-ACD1-694991E48904

Q34184485-16868B07-A79F-4231-90F4-7FB63437324C

Q34184485-1DEE560F-D491-470A-B6FF-CFCA259BC723

Q34184485-2CC4075A-47E7-4021-ADB4-17EC5EDBCFD2

Q34184485-32B4BCC8-1A62-4DDB-B0B1-12238C404EDA

Q34184485-39603CD8-8492-40CA-95EB-578DFE77AEFF

Q34184485-500E57F3-9467-4AE6-BDC8-AFDC445D8082

Q34184485-57425F28-88AA-4798-8497-01CA9D572994

Q34184485-5D1EC1EA-2367-464F-98CA-84BC3F3A452F

Q34184485-5D7EAE28-911C-4EB3-AF57-8C1362D1F030

P304

Q34184485-4BFA0599-AF0A-4E68-AE5B-BB8ACCFB6C4C

P31

Q34184485-4250EC51-D814-40D8-A0A3-BF7AB56C9B79

P356

Q34184485-B8EF173C-33FC-4AA1-8CE3-D017069113FE

P407

Q34184485-45F11476-5551-4A37-8671-8B205F15F92F

P433

Q34184485-6E05367C-1878-48D9-8D7F-B1448905A9D5

P478

Q34184485-A0F6C795-A02E-4F78-9392-646B93558103

P577

Q34184485-78CD6349-204A-473E-BDFD-2E370517A2CC

P5875

Q34184485-635BC2A9-B909-4451-96D1-6C9F19B7B14E

P698

Q34184485-92FC67C8-2E35-4200-B0E1-363D93642FDC

P356

P1433

Journal of Biological Chemistry

P1476

Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

@en

P2093

Ana M Tari

http://www.w3.org/2001/XMLSchema#string

Gabriel Lopez-Berestein

http://www.w3.org/2001/XMLSchema#string

Rakesh Kumar

http://www.w3.org/2001/XMLSchema#string

Sandip K Mishra

http://www.w3.org/2001/XMLSchema#string

Sangeeta K Cheema

http://www.w3.org/2001/XMLSchema#string

Vivek M Rangnekar

http://www.w3.org/2001/XMLSchema#string

P2860

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1

The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C

Par4 is a coactivator for a splice isoform-specific transcriptional activation domain in WT1

Interaction partners of Dlk/ZIP kinase: co-expression of Dlk/ZIP kinase and Par-4 results in cytoplasmic retention and apoptosis

Treatment options in androgen-independent prostate cancer.

Treatment of locally advanced prostate cancer: is chemotherapy the next step?

Synthetic haptens as probes of antibody response and immunorecognition.

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation.

Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis

P304

19995-20005

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M205865200

http://www.w3.org/2001/XMLSchema#string

P407

P433

22

http://www.w3.org/2001/XMLSchema#string

P478

278

http://www.w3.org/2001/XMLSchema#string

P577

2003-03-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

10850478

http://www.w3.org/2001/XMLSchema#string

P698

12644474

http://www.w3.org/2001/XMLSchema#string