The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.
about
Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylationNuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation.Sox15 and Fhl3 transcriptionally coactivate Foxk1 and regulate myogenic progenitor cellsDifferential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2The LIM-only protein FHL2 is a negative regulator of E4F1Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytesProline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only protein 2Four and a half LIM protein 1 binds myosin-binding protein C and regulates myosin filament formation and sarcomere assemblyThe LIM protein, Limd1, regulates AP-1 activation through an interaction with Traf6 to influence osteoclast developmentTranscriptional regulation of adipogenesis by KLF4JNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stressRegulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1)Activator protein 1 (AP-1) contributes to EpCAM-dependent breast cancer invasion.Deficiency in the LIM-only protein Fhl2 impairs skin wound healingLigand-specific sequential regulation of transcription factors for differentiation of MCF-7 cellsFHL5, a novel actin-binding protein, is highly expressed in eel gill pillar cells and responds to wall tension.Disruption of four-and-a-half LIM 2 decreases bone mineral content and bone mineral density in femur and tibia bones of female mice.The LIM-only protein FHL2 mediates ras-induced transformation through cyclin D1 and p53 pathways.Global analysis of ligand sensitivity of estrogen inducible and suppressible genes in MCF7/BUS breast cancer cells by DNA microarrayDeficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice.Fhl2 deficiency results in osteopenia due to decreased activity of osteoblastsFHL2 inhibits the activated osteoclast in a TRAF6-dependent manner.FHL2 expression in peritumoural fibroblasts correlates with lymphatic metastasis in sporadic but not in HNPCC-associated colon cancer.The LIM domain protein FHL2 interacts with the NR5A family of nuclear receptors and CREB to activate the inhibin-α subunit gene in ovarian granulosa cells.Identification of FHL2-regulated genes in liver by microarray and bioinformatics analysis.Site-specific proteolysis of the transcriptional coactivator HCF-1 can regulate its interaction with protein cofactors.FHL2 silencing reduces Wnt signaling and osteosarcoma tumorigenesis in vitro and in vivo.The diverse biofunctions of LIM domain proteins: determined by subcellular localization and protein-protein interaction.The four and a half LIM family members are novel interactants of the human T-cell leukemia virus type 1 Tax oncoproteinIL-1beta regulates FHL2 and other cytoskeleton-related genes in human chondrocytesRunx3-mediated transcriptional program in cytotoxic lymphocytes.FHL2 regulates hematopoietic stem cell functions under stress conditionsKLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2.The four and a half LIM-only protein 2 (FHL2) activates transforming growth factor β (TGF-β) signaling by regulating ubiquitination of the E3 ligase Arkadia.Abnormal sperm in mice with targeted deletion of the act (activator of cAMP-responsive element modulator in testis) gene.Epithelial expression of FHL2 is negatively associated with metastasis-free and overall survival in colorectal cancerMammalian Actin-binding Protein-1/Hip-55 Interacts with FHL2 and Negatively Regulates Cell InvasionLIM-only protein FHL2 activates NF-κB signaling in the control of liver regeneration and hepatocarcinogenesis.The four and a half LIM domains 2 (FHL2) regulates ovarian granulosa cell tumor progression via controlling AKT1 transcription.FHL1 interacts with oestrogen receptors and regulates breast cancer cell growth
P2860
Q24293737-305115FE-0068-410E-8885-C164BE5F179AQ24294613-3A420E12-3FD2-42E3-9342-014BCF3CDA04Q24300409-65C3D64E-9B4E-47FF-9C0A-E4C2F5424506Q24309987-E0737E2B-D961-45E7-BCAB-A94EDA14313CQ24323174-9641FC3E-0727-4DA0-ABAE-D90CB036902DQ24629352-30CC0EB3-07DA-4823-A4C4-0341C86E6E56Q28280935-638A906D-0507-442A-80B3-FE7CB4BD9025Q28291221-7A13B0FE-17EA-4EB9-A38B-4251904374A0Q28512132-4ACBF424-13DE-41E3-B6BA-641DE150A7CAQ28513402-4C2BFF9E-1D63-45E3-8AE5-76C580AFDB1AQ28910415-D307CD0A-B7B1-4D8B-AF0B-E1838FC4C42EQ30008871-83D94913-876A-4E3F-AF2A-6152F4056EA9Q30427356-4D9AE36C-B5C0-4686-B7BE-321F5D635755Q30480424-3221BECE-DFF0-44D3-8737-C2D1CA1F65E1Q30899153-8DF0D50C-518D-4299-9E02-7CBC03838343Q33205331-594DD6A2-C71A-45BC-88B4-50A16FCC1860Q33254909-7D5383FB-4A99-443D-8D71-B50E26A35488Q33385456-6C65807C-B1C3-4CC2-895A-67B294D48F48Q33714276-C3CBE2CB-50A6-42CA-BC2A-C680D24D8917Q33815903-D19408FC-A927-421F-9490-B65DA340B887Q33947126-C94BF985-688E-45E2-93FD-36AF3A36B83DQ34014506-3D56E528-C4A3-41E7-8870-7A7119476526Q34206722-388DF37D-D5C6-47D1-8FC9-16A62AB5D1BFQ34317218-30BF3F24-4D48-4229-B15B-7DDD24348042Q34399565-9BE9F436-9817-4AC8-ACA6-54B55B7CEB12Q34547044-C8F31673-71BE-4CE0-9FC1-87903FB1CE73Q34575984-930BCB8F-EBEA-4F69-91B2-548E107E878EQ34662765-D1B272D5-6822-4CDD-B1B6-E58A7CC0DBC8Q34686753-1421E652-43E0-4017-A3EA-0AF47693C156Q34742553-912D87BA-90E8-4BEB-B2AD-EB34B64EFC44Q35043957-3AF23E57-E68C-4B5C-954B-3C2401C72BD6Q35137904-17FC8396-6C80-4A9F-A1DE-DA4A4EBE518BQ36413193-32A8B143-FC50-4935-BD51-98D6215495FBQ36543763-EFF720EE-7816-4FCF-BFC0-88635F1F5F80Q36986331-1D141EE7-4BEE-4B5C-9A48-8A8321EAE08BQ37003274-9E69EBAF-94DB-4F6C-B169-D6092FB40E3CQ37065685-27578659-104B-4EE8-8818-73CF3FBE41A2Q37122935-598AA4FB-E3C9-43B3-AFA7-563A79D6F5BAQ37151504-BE1EFFAC-B40C-45FE-B5AB-45D60818F9A2Q37293773-77AF8475-EDB0-41AE-A5B0-7806B5DE190D
P2860
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.
@ast
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.
@en
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.
@nl
type
label
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.
@ast
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.
@en
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.
@nl
prefLabel
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.
@ast
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.
@en
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.
@nl
P2860
P356
P1476
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.
@en
P2093
Aurore Morlon
P2860
P304
P356
10.1073/PNAS.0735923100
P407
P577
2003-03-18T00:00:00Z