Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer. - Wikidata - awgldk - TriplyDB

Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer.

Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer.

http://www.wikidata.org/entity/Q34186022

about

Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors Dopamine D3 Receptor Antagonists as Potential Therapeutics for the Treatment of Neurological Diseases.Allosteric mechanisms within the adenosine A2A-dopamine D2 receptor heterotetramer Hormones and Neuropeptide Receptor Heteromers in the Ventral Tegmental Area. Targets for the Treatment of Loss of Control of Food Intake and Substance Use Disorders The GPCR heterotetramer: challenging classical pharmacology.Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer Mechanisms of the psychostimulant effects of caffeine: implications for substance use disorders.Targeting the dopamine D3 receptor: an overview of drug design strategies.Functional Characterization of a Novel Series of Biased Signaling Dopamine D3 Receptor Agonists.Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis.Enhanced Natriuresis and Diuresis in Wistar Rats Caused by the Costimulation of Renal Dopamine D3 and Angiotensin II Type 2 Receptors.Opposing aging-related shift of excitatory dopamine D1 and inhibitory D3 receptor protein expression in striatum and spinal cord Evidence for Noncanonical Neurotransmitter Activation: Norepinephrine as a Dopamine D2-Like Receptor Agonist A Significant Role of the Truncated Ghrelin Receptor GHS-R1b in Ghrelin-induced Signaling in Neurons.Loss of dopamine D1 receptors and diminished D1/5 receptor-mediated ERK phosphorylation in the periaqueductal gray after spinal cord lesion.Role of iso-receptors in receptor-receptor interactions with a focus on dopamine iso-receptor complexes.Revealing G-protein-coupled receptor oligomerization at the single-molecule level through a nanoscopic lens: methods, dynamics and biological function.D-512, a novel dopamine D2/3 receptor agonist, demonstrates greater anti-Parkinsonian efficacy than ropinirole in Parkinsonian rats.Morphine responsiveness to thermal pain stimuli is aging-associated and mediated by dopamine D1 and D3 receptor interactions.Connectome and molecular pharmacological differences in the dopaminergic system in restless legs syndrome (RLS): plastic changes and neuroadaptations that may contribute to augmentation.Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum.Potential for targeting dopamine/DARPP-32 signaling in neuropsychiatric and neurodegenerative disorders.The dopamine D2 receptor dimer and its interaction with homobivalent antagonists: homology modeling, docking and molecular dynamics Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area.Behavioral control by striatal adenosine A2A -dopamine D2 receptor heteromers.Dopamine D3 Receptor Modulates l-DOPA-Induced Dyskinesia by Targeting D1 Receptor-Mediated Striatal Signaling.Pivotal Role of Adenosine Neurotransmission in Restless Legs Syndrome.Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression.Temporal reprogramming of calcium signalling via crosstalk of gonadotrophin receptors that associate as functionally asymmetric heteromers.Allosterism within delta opioid-kappa opioid receptor heteromers in peripheral sensory neurons: Regulation of kappa opioid agonist efficacy.

P2860

Q27347603-720E2C69-430E-470B-8E56-DEB12AD5A928 Q28067056-BDE9FB03-D7B0-44F9-B3A2-A744001FB305 Q28263053-7C091EA5-564D-468E-8B12-42E26BDE2136 Q33689876-10C72448-5BB9-4098-BDCA-A6274519E32F Q34463989-84CD1542-CEF5-468E-BB9D-764F0B655348 Q34481913-A5EF9311-5A29-4E47-8B8B-AD1956099C46 Q34509861-B6254E0F-27D3-4DD5-9352-23751B85B8A3 Q34524556-B71F71FA-4C32-4D33-8D56-7EBF1BA8FDD1 Q34543859-A7127B7B-15C6-4D73-9474-C4D50E2CEDF2 Q35547856-24B3CAA3-4EFD-4720-8DB4-9CC8D6851429 Q35892818-2902D3FE-9964-4A04-A327-00933BE3D3D2 Q36363450-9CEA885F-893B-42F5-824E-BF44952F5096 Q36598111-3AF07562-C603-4666-AC3C-D4139EF2527C Q36733481-E00787AC-A9B1-47BE-9C37-3DEBF442F688 Q37065864-1833E969-8A0F-4091-B6B6-CC13001CA6CA Q37603968-F69707B2-7D22-47E8-B745-A8A8ADCC701E Q38595178-619DB545-75EA-4BEC-8272-2B28777310D9 Q38618328-84A58691-759C-4FA5-8CBD-5A03BF1B2D12 Q38699002-BA9DBC5B-4D71-432E-BF39-EBD52BE585B7 Q38930685-E6E8DA48-FD23-462A-91FB-D9896FC7C818 Q38931189-2EED37B9-2613-4F9C-A979-AE98BE1212EC Q39013000-DEFC33F7-61A5-485B-98BB-46D3A2058E8E Q39067400-CAD6C442-BC28-4E1B-8486-16BD624E5F15 Q39523785-150AA236-95E0-467B-BC86-75EF735F42AC Q41843746-2D0BE1A2-C6F4-4AD7-9A73-74909FCBAD7D Q47624646-315D3A4E-37A5-4A3A-A557-C78745C2A350 Q47637177-5A74B347-4567-480B-B5AF-A063E81EBBC5 Q47642330-1D3A34CA-EB59-4386-AD2E-7314E62366A8 Q47988327-452A86C8-65BF-4CF2-9BE8-D3A5AA13966C Q48112856-30F69D38-05A5-4FEC-B9B5-49F2F083A981 Q50048275-B4C1518E-6C97-4B31-8060-9304852E0FC5

P2860

Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer.

http://www.wikidata.org/entity/Q34186022

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Functional selectivity of allo ...... D1-D3 receptor heterotetramer.

@ast

Functional selectivity of allo ...... D1-D3 receptor heterotetramer.

@en

Functional selectivity of allo ...... D1-D3 receptor heterotetramer.

@nl

type

label

Functional selectivity of allo ...... D1-D3 receptor heterotetramer.

@ast

Functional selectivity of allo ...... D1-D3 receptor heterotetramer.

@en

Functional selectivity of allo ...... D1-D3 receptor heterotetramer.

@nl

prefLabel

Functional selectivity of allo ...... D1-D3 receptor heterotetramer.

@ast

Functional selectivity of allo ...... D1-D3 receptor heterotetramer.

@en

Functional selectivity of allo ...... D1-D3 receptor heterotetramer.

@nl

P1433

Q34186022-51F615EE-1D4E-42E4-832E-326B9824A92A

P1476

Q34186022-9C93270F-228F-4BA7-BCCF-706C03E05BBC

P2093

Q34186022-0E7EF2AA-592E-4CB9-AD7E-B8ADDD2DA262

Q34186022-14FCE06A-6D84-42A7-B469-642873B616FE

Q34186022-55E7707C-062C-413B-8B13-1EC08BA6473F

Q34186022-676F529A-DC92-473F-AACB-3F5F83CBEE07

Q34186022-744BAF76-C10C-428F-B8B1-F50FEE45F54E

Q34186022-90A33C1C-DCB2-4E8E-995C-E00B7F67929D

Q34186022-A3316DFE-AF94-4906-884F-8F269E1957B3

Q34186022-A65B971E-06C3-4E37-9986-7007B465D0D4

Q34186022-B2BA64F9-4102-4B7C-BED5-160E850444A2

Q34186022-CB8F24BA-ED19-4A0B-B328-4CF9D777CE02

P2860

Q34186022-006B4970-4CC2-4D03-98BA-960581C9AFB0

Q34186022-01E67228-B623-4973-9480-716485CF0F6A

Q34186022-1DB64E4E-FB74-4823-9438-49B97C71C41D

Q34186022-1F0AE753-4243-436C-970E-6C20E312A43B

Q34186022-2F6030E9-2808-4B88-B818-154297B93F67

Q34186022-3B2AE385-5B24-4BBE-9326-DF880477F4B8

Q34186022-3DB10BD2-C2A7-4667-95AE-1222F5333DCC

Q34186022-45772B30-359B-4993-AEE7-342D0804A0C8

Q34186022-53146CF7-3304-479F-84A1-FE79715A9EED

Q34186022-675E2A3D-E8EF-49DE-8FEA-ED35072B75E6

P304

Q34186022-54732F04-D758-4097-BD7B-8CA674E82140

P31

Q34186022-02FF1421-8686-4B3C-BE79-B9B46BEAC5FE

P356

Q34186022-1B00EB36-0AEB-46AD-99CB-7B42B5E35598

P433

Q34186022-EAE6692B-9A65-4B65-A614-03F92142FE4E

P478

Q34186022-597DD8BB-8792-41A7-8647-E23CEB260824

P50

Q34186022-2AC7D7AA-138E-4636-8F9D-EF29E6AE1D68

Q34186022-2FBA5F37-1FC3-4B7B-8FF5-4FD5C34DE59D

Q34186022-39BC498E-A005-429A-8B6F-6B29DBEA2312

Q34186022-818C418E-62F0-4F3E-ADEA-2A3C6A286192

P577

Q34186022-4E7F3568-BE86-444B-9A30-F1001F070429

P5875

Q34186022-48177688-8FDC-430C-8CD4-C60409CE5355

P698

Q34186022-23B672D2-6CE3-41B9-AB60-E73A4CED2C4F

P921

Q34186022-08660CEA-BBB3-43FB-A9D1-6FF328F24D0D

Q34186022-e2e87d5f-ed3a-41a2-9651-3ac4131d9376

P932

Q34186022-73CB8C41-56EA-4718-B027-55D91BB5F6A5

P356

P1433

Molecular Pharmacology

P1476

Functional selectivity of allo ...... D1-D3 receptor heterotetramer

@en

P2093

Antoni Cortés

http://www.w3.org/2001/XMLSchema#string

Carme Lluís

http://www.w3.org/2001/XMLSchema#string

Estefania Moreno

http://www.w3.org/2001/XMLSchema#string

Gemma Navarro

http://www.w3.org/2001/XMLSchema#string

Josefa Mallol

http://www.w3.org/2001/XMLSchema#string

Marta Sánchez-Soto

http://www.w3.org/2001/XMLSchema#string

Ning-Sheng Cai

http://www.w3.org/2001/XMLSchema#string

Sandeep Kumar-Barodia

http://www.w3.org/2001/XMLSchema#string

Vicent Casadó

http://www.w3.org/2001/XMLSchema#string

Xavier Guitart

http://www.w3.org/2001/XMLSchema#string

P2860

Dopamine D2 receptors form higher order oligomers at physiological expression levels

Reciprocal regulation of dopamine D1 and D3 receptor function and trafficking by heterodimerization

Adaptive increase in D3 dopamine receptors in the brain reward circuits of human cocaine fatalities

Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors

Building a new conceptual framework for receptor heteromers

Identification of dopamine D1-D3 receptor heteromers. Indications for a role of synergistic D1-D3 receptor interactions in the striatum

Striatal pre- and postsynaptic profile of adenosine A(2A) receptor antagonists

Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase

Structure-based analysis of GPCR function: evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein.

Uncoupling the dopamine D1-D2 receptor complex exerts antidepressant-like effects.

P304

417-429

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1124/MOL.114.093096

http://www.w3.org/2001/XMLSchema#string

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

86

http://www.w3.org/2001/XMLSchema#string

P50

Enric I. Canela

Peter McCormick

P577

2014-08-05T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

264537974

http://www.w3.org/2001/XMLSchema#string

P698

25097189

http://www.w3.org/2001/XMLSchema#string

P921

G protein-coupled receptor

P932

4164978

http://www.w3.org/2001/XMLSchema#string