Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen. - Wikidata - awgldk - TriplyDB

Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen.

Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen.

http://www.wikidata.org/entity/Q34186414

about

The structural features of Trask that mediate its anti-adhesive functions The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motility Adhesion signaling by a novel mitotic substrate of src kinases CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1.Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia.Characterization of SEZ6L2 cell-surface protein as a novel prognostic marker for lung cancer.New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells.Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta.A rapid subtractive immunization method to prepare discriminatory monoclonal antibodies for food E. coli O157:H7 contamination CDCP1 identifies a CD146 negative subset of marrow fibroblasts involved with cytokine production.Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers.Phosphorylation of Trask by Src kinases inhibits integrin clustering and functions in exclusion with focal adhesion signaling CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.Structural requirements for cub domain containing protein 1 (CDCP1) and Src dependent cell transformation VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration Role of DNA methylation for expression of novel stem cell marker CDCP1 in hematopoietic cells.Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination.Trask phosphorylation defines the reverse mode of a phosphotyrosine signaling switch that underlies cell anchorage state Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells.A tumor-suppressing function in the epithelial adhesion protein Trask.CUB domain containing protein 1 (CDCP1) modulates adhesion and motility in colon cancer cells.Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734 The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration Efficient construct of a large and functional scFv yeast display library derived from the ascites B cells of ovarian cancer patients by three-fragment transformation-associated recombination.ADAM9 enhances CDCP1 protein expression by suppressing miR-218 for lung tumor metastasis.Trask loss enhances tumorigenic growth by liberating integrin signaling and growth factor receptor cross-talk in unanchored cells Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients Dysregulated expression of cell surface glycoprotein CDCP1 in prostate cancer CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma.Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer.The role of membrane microdomains in transmembrane signaling through the epithelial glycoprotein Gp140/CDCP1.Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and metastatic dissemination Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.The transmembrane src substrate Trask is an epithelial protein that signals during anchorage deprivation.CDCP1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer.Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis.Roles of CUB domain-containing protein 1 signaling in cancer invasion and metastasis.Cell surface remodeling by plasmin: a new function for an old enzyme.Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance.

P2860

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P2860

Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen.

http://www.wikidata.org/entity/Q34186414

description

2003 nî lūn-bûn

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2003 թուականի Մարտին հրատարակուած գիտական յօդուած

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2003 թվականի մարտին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Subtractive immunization using ...... orylated glycoprotein antigen.

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Subtractive immunization using ...... orylated glycoprotein antigen.

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Subtractive immunization using ...... orylated glycoprotein antigen.

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Subtractive immunization using ...... orylated glycoprotein antigen.

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Subtractive immunization using ...... orylated glycoprotein antigen.

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Subtractive immunization using ...... orylated glycoprotein antigen.

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Subtractive immunization using ...... orylated glycoprotein antigen.

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Subtractive immunization using ...... orylated glycoprotein antigen.

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Subtractive immunization using ...... orylated glycoprotein antigen.

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P1433

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P1433

P1476

Subtractive immunization using ...... horylated glycoprotein antigen

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P2093

David Tarin

http://www.w3.org/2001/XMLSchema#string

Gisela F Claassen

http://www.w3.org/2001/XMLSchema#string

Hongyan Liang

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Jacqueline E Testa

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James P Quigley

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Ronald T Aimes

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P2860

SMART, a simple modular architecture research tool: identification of signaling domains

Sequence and structure-based prediction of eukaryotic protein phosphorylation sites

Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymes

Stoichiometry of complexes between mannose-binding protein and its associated serine proteases. Defining functional units for complement activation

Identification and characterization of two distinct ligand binding regions of cubilin

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

The CUB domain. A widespread module in developmentally regulated proteins.

Homogeneous glycopeptides and glycoproteins for biological investigation.

Peripheral T-cell tolerance induced in naive and primed mice by subcutaneous injection of peptides from the major cat allergen Fel d I

Predicting the orientation of eukaryotic membrane-spanning proteins.

P2888

P304

1783-1794

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scholarly article

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10.1038/SJ.ONC.1206220

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P407

P433

12

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P478

22

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P50

Andries Zijlstra

P577

2003-03-01T00:00:00Z

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7816509

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P6179

1036369351

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12660814

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P921

phosphorylation