A tripartite motif protein TRIM11 binds and destabilizes Humanin, a neuroprotective peptide against Alzheimer's disease-relevant insults.
about
A screen for proteins that interact with PAX6: C-terminal mutations disrupt interaction with HOMER3, DNCL1 and TRIM11Cloning and characterization of a novel human SPRYD4 gene encoding a putative SPRY domain-containing proteinInteraction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosisTRIM11 binds to and destabilizes a key component of the activator-mediated cofactor complex (ARC105) through the ubiquitin-proteasome systemTRIM E3 ligases interfere with early and late stages of the retroviral life cycleA novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradationStructural and functional insights into the B30.2/SPRY domain.The emerging role of the mitochondrial-derived peptide humanin in stress resistanceTRIM family proteins and their emerging roles in innate immunityLoss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancerTrim11 modulates the function of neurogenic transcription factor Pax6 through ubiquitin-proteosome systemA specific region of 37 amino acid residues in the SPRY (B30.2) domain of African green monkey TRIM5alpha determines species-specific restriction of simian immunodeficiency virus SIVmac infection.APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease.FBXL21 association with schizophrenia in Irish family and case-control samples.Species-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restrictionThe human antiviral factor TRIM11 is under the regulation of HIV-1 Vpr.Mitochondrial stress signaling in longevity: a new role for mitochondrial function in agingHumanin and age-related diseases: a new link?Humanin binds MPP8: mapping interaction sites of the peptide and protein.TRIM11 negatively regulates IFNβ production and antiviral activity by targeting TBK1TRIM32 protein sensitizes cells to tumor necrosis factor (TNFα)-induced apoptosis via its RING domain-dependent E3 ligase activity against X-linked inhibitor of apoptosis (XIAP).Role of TRIM5α RING domain E3 ubiquitin ligase activity in capsid disassembly, reverse transcription blockade, and restriction of simian immunodeficiency virus.Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha.Expression of butyrophilin (Btn1a1) in lactating mammary gland is essential for the regulated secretion of milk-lipid droplets.Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain.The role of ubiquitin-protein ligases in neurodegenerative disease.Secreted calmodulin-like skin protein inhibits neuronal death in cell-based Alzheimer's disease models via the heterotrimeric Humanin receptorBiochemical and biophysical characterization of a chimeric TRIM21-TRIM5alpha proteinTRIM11 overexpression promotes proliferation, migration and invasion of lung cancer cellsCommon disease signatures from gene expression analysis in Huntington's disease human blood and brainTRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth.Strategies for the identification of ubiquitin ligase inhibitors.TRIM11, a direct target of miR-24-3p, promotes cell proliferation and inhibits apoptosis in colon cancer.Protective effects of Humanin and calmodulin-like skin protein in Alzheimer's disease and broad range of abnormalities.Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer cell proliferation in vitro and in vivo.Humanin: Functional Interfaces with IGF-I.The E3 ubiquitin ligase TRIM11 mediates the degradation of congenital central hypoventilation syndrome-associated polyalanine-expanded PHOX2B.Functional interactions between ubiquitin E2 enzymes and TRIM proteins.Trim11 increases expression of dopamine beta-hydroxylase gene by interacting with Phox2b.Proliferation and invasion of ovarian cancer cells are suppressed by knockdown of TRIM11.
P2860
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P2860
A tripartite motif protein TRIM11 binds and destabilizes Humanin, a neuroprotective peptide against Alzheimer's disease-relevant insults.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
A tripartite motif protein TRI ...... er's disease-relevant insults.
@ast
A tripartite motif protein TRI ...... er's disease-relevant insults.
@en
A tripartite motif protein TRI ...... er's disease-relevant insults.
@nl
type
label
A tripartite motif protein TRI ...... er's disease-relevant insults.
@ast
A tripartite motif protein TRI ...... er's disease-relevant insults.
@en
A tripartite motif protein TRI ...... er's disease-relevant insults.
@nl
prefLabel
A tripartite motif protein TRI ...... er's disease-relevant insults.
@ast
A tripartite motif protein TRI ...... er's disease-relevant insults.
@en
A tripartite motif protein TRI ...... er's disease-relevant insults.
@nl
P2093
P2860
P1476
A tripartite motif protein TRI ...... er's disease-relevant insults.
@en
P2093
Hirohisa Tajima
Ikuo Nishimoto
Kenzo Terashita
Masaoki Kawasumi
Miho Ishizaka
Mikiro Nawa
Sadakazu Aiso
Takako Niikura
Yohichi Yamagishi
Yuichi Hashimoto
P2860
P304
P356
10.1046/J.1460-9568.2003.02553.X
P407
P577
2003-03-01T00:00:00Z