Directed evolution of novel adeno-associated viruses for therapeutic gene delivery. - Wikidata - awgldk - TriplyDB

Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.

Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.

http://www.wikidata.org/entity/Q34188892

about

Gene therapy for hemophilia E Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal--Tailored Acceleration of AAV Evolution Barriers to inhaled gene therapy of obstructive lung diseases: A review Applying evolutionary biology to address global challenges.SCHEMA computational design of virus capsid chimeras: calibrating how genome packaging, protection, and transduction correlate with calculated structural disruption.A viral over-expression system for the major malaria mosquito Anopheles gambiae.Adeno-associated virus: fit to serve Novel adeno-associated viruses derived from pig tissues transduce most major organs in mice.Gene replacement therapies for duchenne muscular dystrophy using adeno-associated viral vectors.Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors.An experimental and computational evolution-based method to study a mode of co-evolution of overlapping open reading frames in the AAV2 viral genome.High capsid-genome correlation facilitates creation of AAV libraries for directed evolution Reprogramming Immune Response With Capsid-Optimized AAV6 Vectors for Immunotherapy of Cancer In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy Strategies to circumvent humoral immunity to adeno-associated viral vectors.Long-term robust myocardial transduction of the dog heart from a peripheral vein by adeno-associated virus serotype-8.Immune responses to AAV vectors: overcoming barriers to successful gene therapy Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system.The MRI contrast agent gadoteridol enhances distribution of rAAV1 in the rat hippocampus.AAV Vectors Vaccines Against Infectious Diseases.Antisense gene silencing: therapy for neurodegenerative disorders?Effect of bortezomib on the efficacy of AAV9.SERCA2a treatment to preserve cardiac function in a rat pressure-overload model of heart failure.Advances in homology directed genetic engineering of human pluripotent and adult stem cells.Mapping the AAV Capsid Host Antibody Response toward the Development of Second Generation Gene Delivery Vectors Advances in AAV vector development for gene therapy in the retina.Gene therapy for the neurological manifestations in lysosomal storage disorders.Gene therapy for restoring heart rhythm.Current status of haemophilia gene therapy.Engineering adeno-associated viruses for clinical gene therapy.Gene therapies for inherited retinal disorders.Harnessing the Therapeutic Potential of MicroRNAs for Cardiovascular Disease.Beyond traditional pharmacology: new tools and approaches.CRISPR-Cas9: a new and promising player in gene therapy.Adeno-associated virus (AAV) vectors in cancer gene therapy.The CRF family of neuropeptides and their receptors - mediators of the central stress response.Development of novel AAV serotype 6 based vectors with selective tropism for human cancer cells.Prolonged expression of an anti-HIV-1 gp120 minibody to the female rhesus macaque lower genital tract by AAV gene transfer Adeno-Associated Virus (AAV) as a Vector for Gene Therapy.Nanoparticles for gene delivery.

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Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.

http://www.wikidata.org/entity/Q34188892

description

2012 nî lūn-bûn

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2012 թուականի Մարտին հրատարակուած գիտական յօդուած

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2012 թվականի մարտին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.

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Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.

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Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.

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type

label

Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.

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Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.

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Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.

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prefLabel

Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.

@ast

Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.

@en

Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.

@nl

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Directed evolution of novel adeno-associated viruses for therapeutic gene delivery

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D V Schaffer

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M A Bartel

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P2860

A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells

Site-specific integration by adeno-associated virus

A viral assembly factor promotes AAV2 capsid formation in the nucleolus

Exploring protein fitness landscapes by directed evolution

Safety and efficacy of gene transfer for Leber's congenital amaurosis

Directed evolution of adeno-associated virus to an infectious respiratory virus

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

Effect of gene therapy on visual function in Leber's congenital amaurosis

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

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694-700

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10.1038/GT.2012.20

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6

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19

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John R Weinstein

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2012-03-08T00:00:00Z

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221688303

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22402323

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directed evolution