3-Deazaneplanocin A: a new inhibitor of S-adenosylhomocysteine synthesis and its effects in human colon carcinoma cells.
about
Broad-spectrum antiviral activities of neplanocin A, 3-deazaneplanocin A, and their 5'-nor derivativesRelationship between intracellular concentration of S-adenosylhomocysteine and inhibition of vaccinia virus replication and inhibition of murine L-929 cell growth.Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.3-Deazaneplanocin A (DZNep), an inhibitor of S-adenosylmethionine-dependent methyltransferase, promotes erythroid differentiation.Promotion of glioblastoma cell motility by enhancer of zeste homolog 2 (EZH2) is mediated by AXL receptor kinaseInhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer(-)-Epigallocatechin-3-gallate and DZNep reduce polycomb protein level via a proteasome-dependent mechanism in skin cancer cells9-(trans-2',trans-3'-Dihydroxycyclopent-4'-enyl)-adenine and -3-deazaadenine: analogs of neplanocin A which retain potent antiviral activity but exhibit reduced cytotoxicity.Survival of skin cancer stem cells requires the Ezh2 polycomb group protein.Molecular mechanisms involved in the synergistic interaction of the EZH2 inhibitor 3-deazaneplanocin A with gemcitabine in pancreatic cancer cells.Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cellsInhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cellsEpigenetic cancer prevention mechanisms in skin cancer.Epigenetic modifications in prostate cancer.The role of polycomb repressive complexes in biliary tract cancer.Anti-inflammatory and chondroprotective effects of the S-adenosylhomocysteine hydrolase inhibitor 3-Deazaneplanocin A, in human articular chondrocytes.EZH2 inhibitors: a patent review (2014-2016).DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice.EZH2 regulates spinal neuroinflammation in rats with neuropathic pain.
P2860
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P2860
3-Deazaneplanocin A: a new inhibitor of S-adenosylhomocysteine synthesis and its effects in human colon carcinoma cells.
description
1986 nî lūn-bûn
@nan
1986 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
name
3-Deazaneplanocin A: a new inh ...... n human colon carcinoma cells.
@ast
3-Deazaneplanocin A: a new inh ...... n human colon carcinoma cells.
@en
3-Deazaneplanocin A: a new inh ...... n human colon carcinoma cells.
@nl
type
label
3-Deazaneplanocin A: a new inh ...... n human colon carcinoma cells.
@ast
3-Deazaneplanocin A: a new inh ...... n human colon carcinoma cells.
@en
3-Deazaneplanocin A: a new inh ...... n human colon carcinoma cells.
@nl
prefLabel
3-Deazaneplanocin A: a new inh ...... n human colon carcinoma cells.
@ast
3-Deazaneplanocin A: a new inh ...... n human colon carcinoma cells.
@en
3-Deazaneplanocin A: a new inh ...... n human colon carcinoma cells.
@nl
P2093
P1476
3-Deazaneplanocin A: a new inh ...... n human colon carcinoma cells.
@en
P2093
D R Haines
R I Glazer
V E Marquez
P304
P356
10.1016/0006-2952(86)90774-4
P407
P577
1986-12-01T00:00:00Z