Large molecule bioanalysis using Q-TOF without predigestion and its data processing challenges.
about
Qualification and application of a liquid chromatography-quadrupole time-of-flight mass spectrometric method for the determination of trastuzumab in rat plasma.Using high-resolution quadrupole TOF technology in DMPK analyses.Application and challenges in using LC-MS assays for absolute quantitative analysis of therapeutic proteins in drug discovery.Quantitation of human peptides and proteins via MS: review of analytically validated assays.Applications of low-flow LC-SRM for the analysis of large molecules in pharmaceutical R&D.LC-MS-based quantification of intact proteins: perspective for clinical and bioanalytical applications.Utilizing enzymatic digestion procedures in the bioanalytical laboratory.High-resolution MS in regulated bioanalysis: where are we now and where do we go from here?Applications of high-resolution MS in bioanalysis.HRMS using a Q-Exactive series mass spectrometer for regulated quantitative bioanalysis: how, when, and why to implement.Application of high-resolution MS for development of peptide and large-molecule drug candidates.The use of generic surrogate peptides for the quantitative analysis of human immunoglobulin G1 in pre-clinical species with high-resolution mass spectrometry.2013 White Paper on recent issues in bioanalysis: 'hybrid'--the best of LBA and LCMS.Validation of hepcidin quantification in plasma using LC-HRMS and discovery of a new hepcidin isoform.Large-molecule quantification: sensitivity and selectivity head-to-head comparison of triple quadrupole with Q-TOF.Characterization and quantification of oxyntomodulin in human and rat plasma using high-resolution accurate mass LC-MS.Toward best practices in data processing and analysis for intact biotherapeutics by MS in quantitative bioanalysis.A Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometric Assay for the Quantification of Fabry Disease Biomarker Globotriaosylceramide (GB3) in Fabry Model Mouse.
P2860
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P2860
Large molecule bioanalysis using Q-TOF without predigestion and its data processing challenges.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
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2012 թվականի մարտին հրատարակված գիտական հոդված
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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name
Large molecule bioanalysis usi ...... ts data processing challenges.
@ast
Large molecule bioanalysis usi ...... ts data processing challenges.
@en
Large molecule bioanalysis usi ...... ts data processing challenges.
@nl
type
label
Large molecule bioanalysis usi ...... ts data processing challenges.
@ast
Large molecule bioanalysis usi ...... ts data processing challenges.
@en
Large molecule bioanalysis usi ...... ts data processing challenges.
@nl
prefLabel
Large molecule bioanalysis usi ...... ts data processing challenges.
@ast
Large molecule bioanalysis usi ...... ts data processing challenges.
@en
Large molecule bioanalysis usi ...... ts data processing challenges.
@nl
P2860
P356
P1433
P1476
Large molecule bioanalysis usi ...... ts data processing challenges.
@en
P2093
Fabio Garofolo
Suma Ramagiri
P2860
P304
P356
10.4155/BIO.12.10
P577
2012-03-01T00:00:00Z