Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain.
about
In vitro binding of the asialoglycoprotein receptor to the beta adaptin of plasma membrane coated vesiclesHuman genes involved in cholesterol metabolism: chromosomal mapping of the loci for the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase with cDNA probesThe LDL receptorHepatitis C Virus entry: the early steps in the viral replication cycleAtomic structure of the autosomal recessive hypercholesterolemia phosphotyrosine-binding domain in complex with the LDL-receptor tailThematic review series: the pathogenesis of atherosclerosis: an interpretive history of the cholesterol controversy, part III: mechanistically defining the role of hyperlipidemiaThe adaptor protein AP-3 is required for CD1d-mediated antigen presentation of glycosphingolipids and development of Valpha14i NKT cellsEndocytosis of the class I major histocompatibility antigen via a phorbol myristate acetate-inducible pathway is a cell-specific phenomenon and requires the cytoplasmic domain.Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases.Nonsense mutations in the human beta-globin gene affect mRNA metabolism.Isolation and sequence of a cDNA clone encoding the 31-kDa subunit of bovine kidney vacuolar H+-ATPaseCytoplasmic domain affects membrane expression and function of an Ia molecule.Nine cystic fibrosis patients homozygous for the CFTR nonsense mutation R1162X have mild or moderate lung disease.Four DNA polymorphisms in the LDL receptor gene: their genetic relationship and use in the study of variation at the LDL receptor locus.Recognition of sorting signals by clathrin adaptors.Finnish type of low density lipoprotein receptor gene mutation (FH-Helsinki) deletes exons encoding the carboxy-terminal part of the receptor and creates an internalization-defective phenotypeMutations in the cytoplasmic domain of EGF receptor affect EGF binding and receptor internalization.Reconstitution of vesicle fusions occurring in endocytosis with a cell-free system.Purification and properties of a new clathrin assembly protein.Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbit.A methodology for multivariate phenotype-based genome-wide association studies to mine pleiotropic genesReceptor-mediated endocytosisFunctional domains of the poliovirus receptor.Nonpolarized secretion of truncated forms of the influenza hemagglutinin and the vesicular stomatitus virus G protein from MDCK cells.Polymorphic DNA haplotypes at the LDL receptor locusAdvantages and versatility of fluorescence-based methodology to characterize the functionality of LDLR and class mutation assignment.Multiple crm- mutations in familial hypercholesterolemia. Evidence for 13 alleles, including four deletionsThe familial hypercholesterolemia (FH)-North Karelia mutation of the low density lipoprotein receptor gene deletes seven nucleotides of exon 6 and is a common cause of FH in Finland.Exon-Alu recombination deletes 5 kilobases from the low density lipoprotein receptor gene, producing a null phenotype in familial hypercholesterolemiaNew liver cell mutants defective in the endocytic pathwayBiosynthesis and intracellular sorting of growth hormone-viral envelope glycoprotein hybrids.Heterologous transmembrane and cytoplasmic domains direct functional chimeric influenza virus hemagglutinins into the endocytic pathwayUnusual forms of low density lipoprotein receptors in hamster cell mutants with defects in the receptor structural geneCytoplasmic domains of cellular and viral integral membrane proteins substitute for the cytoplasmic domain of the vesicular stomatitis virus glycoprotein in transport to the plasma membrane.Analysis of progressive deletions of the transmembrane and cytoplasmic domains of influenza hemagglutininPotassium-dependent assembly of coated pits: new coated pits form as planar clathrin lattices.A specific transmembrane domain of a coronavirus E1 glycoprotein is required for its retention in the Golgi region.Effects of mutations in three domains of the vesicular stomatitis viral glycoprotein on its lateral diffusion in the plasma membraneDifferential effects of mutations in three domains on folding, quaternary structure, and intracellular transport of vesicular stomatitis virus G protein.Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization.
P2860
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P2860
Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain.
description
1985 nî lūn-bûn
@nan
1985 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1985 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
name
Internalization-defective LDL ...... uncate the cytoplasmic domain.
@ast
Internalization-defective LDL ...... uncate the cytoplasmic domain.
@en
Internalization-defective LDL ...... uncate the cytoplasmic domain.
@nl
type
label
Internalization-defective LDL ...... uncate the cytoplasmic domain.
@ast
Internalization-defective LDL ...... uncate the cytoplasmic domain.
@en
Internalization-defective LDL ...... uncate the cytoplasmic domain.
@nl
prefLabel
Internalization-defective LDL ...... uncate the cytoplasmic domain.
@ast
Internalization-defective LDL ...... uncate the cytoplasmic domain.
@en
Internalization-defective LDL ...... uncate the cytoplasmic domain.
@nl
P2093
P1433
P1476
Internalization-defective LDL ...... uncate the cytoplasmic domain.
@en
P2093
D W Russell
J L Goldstein
M A Lehrman
W J Schneider
P304
P356
10.1016/S0092-8674(85)80054-4
P407
P577
1985-07-01T00:00:00Z