Beneficial metabolic effects caused by persistent activation of beta-cell M3 muscarinic acetylcholine receptors in transgenic mice.
about
Muscarinic control of MIN6 pancreatic β cells is enhanced by impaired amino acid signaling.Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor.Novel insights into the function of β-cell M3 muscarinic acetylcholine receptors: therapeutic implications.Targeted deletion of one or two copies of the G protein β subunit Gβ5 gene has distinct effects on body weight and behavior in mice.Spinophilin as a novel regulator of M3 muscarinic receptor-mediated insulin release in vitro and in vivo.Early postnatal low-protein nutrition, metabolic programming and the autonomic nervous system in adult life.CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo.Critical metabolic roles of β-cell M3 muscarinic acetylcholine receptorsMinireview: Novel aspects of M3 muscarinic receptor signaling in pancreatic β-cells.Muscarinic receptors as model targets and antitargets for structure-based ligand discovery.Nervous glucose sensing regulates postnatal β cell proliferation and glucose homeostasis.Employing novel animal models in the design of clinically efficacious GPCR ligands.Muscarinic acetylcholine receptors: novel opportunities for drug development.Effect of hyperglycaemia on muscarinic M3 receptor expression and secretory sensitivity to cholinergic receptor activation in islets.The role of M(3)-muscarinic receptor signaling in insulin secretion.Gene Editing, Gene Therapy, and Cell Xenotransplantation: Cell Transplantation Across Species.Inhibition of cholinergic potentiation of insulin secretion from pancreatic islets by chronic elevation of glucose and fatty acids: Protection by casein kinase 2 inhibitor.Acetylcholine induces fibrogenic effects via M2/M3 acetylcholine receptors in non-alcoholic steatohepatitis and in primary human hepatic stellate cells.Transgenic Expression of Glucagon-Like Peptide-1 (GLP-1) and Activated Muscarinic Receptor (M3R) Significantly Improves Pig Islet Secretory Function.Impaired β-cell function in the adult offspring of rats fed a protein-restricted diet during lactation is associated with changes in muscarinic acetylcholine receptor subtypes.Disruption and stabilization of β-cell actin microfilaments differently influence insulin secretion triggered by intracellular Ca2+ mobilization or store-operated Ca2+ entry.
P2860
Q33619580-8DCB967B-5560-4871-8184-6353BDC069ACQ34376884-2FA4B743-C733-42E8-BD1C-6323D7C51D05Q34625376-4433E76D-5EAE-4029-AFF9-5C9D8BDC3BA2Q35497109-252F6541-CFA3-4D4E-9278-62156A5AC3A2Q36252363-5B962AD1-E50D-4DBD-B454-FABAA45AF298Q36295132-E09996F5-40AF-4330-BA45-1420C4C5A8D2Q36371495-4DEDA0C7-761E-43EA-9DBD-36E914BF8FD1Q36599383-0671B3A9-595E-4EC8-8D8B-6B9D2259ED45Q37050369-C22D3C37-5E7E-4552-AE5A-9A8C5F50C37AQ37193147-830DFDF1-1AEE-4D55-829F-3C18D9549C65Q37410576-3B767ED0-0680-4ADB-812C-530AFB54D547Q38200338-400F63FF-A071-4BAB-B6FD-E2C45033D2BFQ38218059-382A61EC-AA31-445B-8C11-D9288AC88D3CQ38307846-57B35453-37B1-4D05-99AB-779942D13793Q38577501-6F7C6F96-B93B-49C9-9AF8-CECCA31603EEQ41563981-ED6438A0-EE21-4E81-917C-99D0286206E7Q42377921-547BA38E-7F5E-4CCD-83FB-807A0A00667FQ42481066-B1BAEB9E-D7DA-4E96-9D5C-D073C61BB113Q42502862-A6689CCE-607A-4F3A-8DB7-83BD2A6D4452Q45369965-B31D024A-5BEB-405B-BC7E-E257B52AC9F4Q52619261-A5602BFE-9A7F-4236-BD66-D9A8E4BFAA23
P2860
Beneficial metabolic effects caused by persistent activation of beta-cell M3 muscarinic acetylcholine receptors in transgenic mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Beneficial metabolic effects c ...... receptors in transgenic mice.
@ast
Beneficial metabolic effects c ...... receptors in transgenic mice.
@en
Beneficial metabolic effects c ...... receptors in transgenic mice.
@nl
type
label
Beneficial metabolic effects c ...... receptors in transgenic mice.
@ast
Beneficial metabolic effects c ...... receptors in transgenic mice.
@en
Beneficial metabolic effects c ...... receptors in transgenic mice.
@nl
prefLabel
Beneficial metabolic effects c ...... receptors in transgenic mice.
@ast
Beneficial metabolic effects c ...... receptors in transgenic mice.
@en
Beneficial metabolic effects c ...... receptors in transgenic mice.
@nl
P2093
P2860
P356
P1433
P1476
Beneficial metabolic effects c ...... receptors in transgenic mice.
@en
P2093
Dinesh Gautam
Inigo Ruiz de Azua
Jean-Marc Guettier
Jian Hua Li
Jürgen Wess
Oksana Gavrilova
Thomas Heard
Walter S Zawalich
William Jou
P2860
P304
P356
10.1210/EN.2010-0519
P407
P577
2010-09-15T00:00:00Z