Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes.
about
CRISPR/Cas9-mediated gene editing in human tripronuclear zygotesNutritional and Nanotechnological Modulators of MicrogliaCRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseasesCRISPR/Cas9 mediated genome editing in ES cells and its application for chimeric analysis in miceUsing CRISPR/Cas to study gene function and model disease in vivoApplications of CRISPR/Cas9 for Gene Editing in Hereditary Movement DisordersNovel Hypomorphic Alleles of the Mouse Tyrosinase Gene Induced by CRISPR-Cas9 Nucleases Cause Non-Albino Pigmentation PhenotypesCRISPR-Cas Genome Surgery in Ophthalmology.CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome.A CRISPR view of development.Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNAA mouse geneticist's practical guide to CRISPR applications.Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers.Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.CRISPR-engineered mosaicism rapidly reveals that loss of Kcnj13 function in mice mimics human disease phenotypes.Sox4 regulates choroid fissure closure by limiting Hedgehog signaling during ocular morphogenesis.Insertion of sequences at the original provirus integration site of mouse ROSA26 locus using the CRISPR/Cas9 system.Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem CellsBrains, genes, and primates.Pervasive Genotypic Mosaicism in Founder Mice Derived from Genome Editing through Pronuclear InjectionGeneration of mutant mice via the CRISPR/Cas9 system using FokI-dCas9Purloined mechanisms of bacterial immunity can cure muscular dystrophy.The Expression of TALEN before Fertilization Provides a Rapid Knock-Out Phenotype in Xenopus laevis Founder Embryos.Efficient identification of CRISPR/Cas9-induced insertions/deletions by direct germline screening in zebrafish.Generation of an Oocyte-Specific Cas9 Transgenic Mouse for Genome Editing.Phospholamban Ablation Using CRISPR/Cas9 System Improves Mortality in a Murine Heart Failure Model.Maternal Supply of Cas9 to Zygotes Facilitates the Efficient Generation of Site-Specific Mutant Mouse Models.Rapid reverse genetic screening using CRISPR in zebrafish.The complex genetics of hypoplastic left heart syndrome.A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular ResearchCRISPR/Cas9-Mediated Insertion of loxP Sites in the Mouse Dock7 Gene Provides an Effective Alternative to Use of Targeted Embryonic Stem Cells.Utilization of the CRISPR/Cas9 system for the efficient production of mutant mice using crRNA/tracrRNA with Cas9 nickase and FokI-dCas9.Efficient Production of Gene-Modified Mice using Staphylococcus aureus Cas9.Microinjection-based generation of mutant mice with a double mutation and a 0.5 Mb deletion in their genome by the CRISPR/Cas9 system.Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment.Promoting Cas9 degradation reduces mosaic mutations in non-human primate embryosCRISPR/Cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method.Optimization of the production of knock-in alleles by CRISPR/Cas9 microinjection into the mouse zygote.Sharing mutations: are biobanks still required in the post-CRISPR/Cas9 era?Modeling Disease In Vivo With CRISPR/Cas9.
P2860
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P2860
Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Somatic mosaicism and allele c ...... A injections in mouse zygotes.
@ast
Somatic mosaicism and allele c ...... A injections in mouse zygotes.
@en
Somatic mosaicism and allele c ...... A injections in mouse zygotes.
@nl
type
label
Somatic mosaicism and allele c ...... A injections in mouse zygotes.
@ast
Somatic mosaicism and allele c ...... A injections in mouse zygotes.
@en
Somatic mosaicism and allele c ...... A injections in mouse zygotes.
@nl
prefLabel
Somatic mosaicism and allele c ...... A injections in mouse zygotes.
@ast
Somatic mosaicism and allele c ...... A injections in mouse zygotes.
@en
Somatic mosaicism and allele c ...... A injections in mouse zygotes.
@nl
P2093
P2860
P1476
Somatic mosaicism and allele c ...... A injections in mouse zygotes.
@en
P2093
Chad N Smith
James F Martin
Jan Parker-Thornburg
Jian Min Deng
Paul G Swinton
Richard R Behringer
Shireen J Usman
P2860
P356
10.1016/J.YDBIO.2014.06.017
P407
P577
2014-06-28T00:00:00Z