An experimentally informed evolutionary model improves phylogenetic fit to divergent lactamase homologs

An experimentally informed evolutionary model improves phylogenetic fit to divergent lactamase homologs

Item
http://www.wikidata.org/entity/Q34201879
Causes of evolutionary rate variation among protein sitesDetection and sequence/structure mapping of biophysical constraints to protein variation in saturated mutational libraries and protein sequence alignments with a dedicated serverSoftware for the analysis and visualization of deep mutational scanning data.The relationship between dN/dS and scaled selection coefficients.How structural and physicochemical determinants shape sequence constraints in a functional enzymeExperimental Estimation of the Effects of All Amino-Acid Mutations to HIV's Envelope Protein on Viral Replication in Cell CultureSite-Specific Amino Acid Preferences Are Mostly Conserved in Two Closely Related Protein Homologs.SHV-129: A Gateway to Global Suppressors in the SHV β-Lactamase Family?Accurate Measurement of the Effects of All Amino-Acid Mutations on Influenza Hemagglutinin.Identification of positive selection in genes is greatly improved by using experimentally informed site-specific models.phydms: software for phylogenetic analyses informed by deep mutational scanning.Extensively Parameterized Mutation-Selection Models Reliably Capture Site-Specific Selective Constraint.Detecting Adaptation in Protein-Coding Genes Using a Bayesian Site-Heterogeneous Mutation-Selection Codon Substitution Model.Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints.Mapping mutational effects along the evolutionary landscape of HIV envelope.Modeling site-specific amino-acid preferences deepens phylogenetic estimates of viral sequence divergenceUsing the Mutation-Selection Framework to Characterize Selection on Protein Sequences
P2860

An experimentally informed evolutionary model improves phylogenetic fit to divergent lactamase homologs

Item
http://www.wikidata.org/entity/Q34201879
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
An experimentally informed evo ...... o divergent lactamase homologs
@ast
An experimentally informed evo ...... o divergent lactamase homologs
@en
An experimentally informed evo ...... o divergent lactamase homologs
@nl
type
label
An experimentally informed evo ...... o divergent lactamase homologs
@ast
An experimentally informed evo ...... o divergent lactamase homologs
@en
An experimentally informed evo ...... o divergent lactamase homologs
@nl
prefLabel
An experimentally informed evo ...... o divergent lactamase homologs
@ast
An experimentally informed evo ...... o divergent lactamase homologs
@en
An experimentally informed evo ...... o divergent lactamase homologs
@nl
P1433
P1476
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
An experimentally informed evo ...... o divergent lactamase homologs
@en
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932