A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity. - Wikidata - awgldk - TriplyDB

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

http://www.wikidata.org/entity/Q34205743

about

Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytes Genome-scale engineering for systems and synthetic biology Programmable DNA-binding proteins from Burkholderia provide a fresh perspective on the TALE-like repeat domain Targeting DNA With Fingers and TALENs Precision editing of large animal genomes Newer gene editing technologies toward HIV gene therapy A TALE of two nucleases: gene targeting for the masses?In Vivo Delivery Systems for Therapeutic Genome Editing Genome-editing Technologies for Gene and Cell Therapy Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing Origins of Programmable Nucleases for Genome Engineering Minimizing off-Target Mutagenesis Risks Caused by Programmable Nucleases Applications of Engineered DNA-Binding Molecules Such as TAL Proteins and the CRISPR/Cas System in Biology Research Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools Designed nucleases for targeted genome editing Progress toward curing HIV infection with hematopoietic cell transplantation CCR5 Targeted Cell Therapy for HIV and Prevention of Viral Escape Bone Marrow Gene Therapy for HIV/AIDS Investigation of Rett syndrome using pluripotent stem cells Pluripotent stem cells and gene therapy Cutting-edge microfabricated biomedical tools for human pluripotent stem cell research Transcription activator-like effectors: a toolkit for synthetic biology Epigenome engineering in cancer: fairytale or a realistic path to the clinic?The role of single-cell analyses in understanding cell lineage commitment Gene therapy on the move Making designer mutants in model organisms Progress and prospects of engineered sequence-specific DNA modulating technologies for the management of liver diseases Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9 Current translational and clinical practices in hematopoietic cell and gene therapy Molecular dynamics simulations of DNA-free and DNA-bound TAL effectors Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region Recent Developments in Systems Biology and Metabolic Engineering of Plant-Microbe Interactions.Engineering T Cells to Functionally Cure HIV-1 Infection Simple and efficient methods for enrichment and isolation of endonuclease modified cells Precise gene modification mediated by TALEN and single-stranded oligodeoxynucleotides in human cells CCR5 gene disruption via lentiviral vectors expressing Cas9 and single guided RNA renders cells resistant to HIV-1 infection CRISPR/Cas9-induced knockout and knock-in mutations in Chlamydomonas reinhardtii Resources for functional genomics studies in Drosophila melanogaster Tipping points in seaweed genetic engineering: scaling up opportunities in the next decade ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

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P2860

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

http://www.wikidata.org/entity/Q34205743

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

A novel TALE nuclease scaffold ...... combination with low toxicity.

@ast

A novel TALE nuclease scaffold ...... combination with low toxicity.

@en

A novel TALE nuclease scaffold ...... combination with low toxicity.

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type

label

A novel TALE nuclease scaffold ...... combination with low toxicity.

@ast

A novel TALE nuclease scaffold ...... combination with low toxicity.

@en

A novel TALE nuclease scaffold ...... combination with low toxicity.

@nl

prefLabel

A novel TALE nuclease scaffold ...... combination with low toxicity.

@ast

A novel TALE nuclease scaffold ...... combination with low toxicity.

@en

A novel TALE nuclease scaffold ...... combination with low toxicity.

@nl

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P1433

Nucleic Acids Research

P1476

A novel TALE nuclease scaffold ...... combination with low toxicity

@en

P2093

Claudio Mussolino

http://www.w3.org/2001/XMLSchema#string

Fabienne Lütge

http://www.w3.org/2001/XMLSchema#string

Nadine Dannemann

http://www.w3.org/2001/XMLSchema#string

Robert Morbitzer

http://www.w3.org/2001/XMLSchema#string

Thomas Lahaye

http://www.w3.org/2001/XMLSchema#string

P2860

Genome editing with modularly assembled zinc-finger nucleases

TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

Targeting DNA double-strand breaks with TAL effector nucleases

Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks

Knockout rats via embryo microinjection of zinc-finger nucleases

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

Targeted chromosomal deletions in human cells using zinc finger nucleases

P304

9283-9293

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P31

scholarly article

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10.1093/NAR/GKR597

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21

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P478

39

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2011-08-03T00:00:00Z

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51544349

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21813459

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P932

3241638

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