Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
about
Lovastatin production by Aspergillus terreus using agro-biomass as substrate in solid state fermentationLost in Translation (LiT): IUPHAR Review 6Increasing disparities between resource inputs and outcomes, as measured by certain health deliverables, in biomedical researchBypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidus2015 Korean Guidelines for the Management of Dyslipidemia: Executive Summary (English Translation)Contributions of risk factors and medical care to cardiovascular mortality trendsThe role of statins in the setting of HIV infectionStatin-Induced Increases in Atrophy Gene Expression Occur Independently of Changes in PGC1α Protein and Mitochondrial ContentIntracellular oxygen determined by respiration regulates localization of Ras and prenylated proteins.Structural analysis of alterations in zebrafish muscle differentiation induced by simvastatin and their recovery with cholesterol.Crystal structure and biochemical studies of the trans-acting polyketide enoyl reductase LovC from lovastatin biosynthesisGenome-wide analysis of sterol-lipid storage and trafficking in Saccharomyces cerevisiae.The Validation of Nematode-Specific Acetylcholine-Gated Chloride Channels as Potential Anthelmintic Drug TargetsHead-to-Head Comparison of Anti-Inflammatory Performance of Known Natural Products In VitroCamphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activityMethod for comparing the structures of protein ligand-binding sites and application for predicting protein-drug interactions.Opportunities to minimise risk in drug discovery and development.Alterations in zebrafish development induced by simvastatin: Comprehensive morphological and physiological study, focusing on muscle.The pleiotropic effects of simvastatin on retinal microvascular endothelium has important implications for ischaemic retinopathiesThe Pathway Less Traveled: Moving from Candidate Genes to Candidate Pathways in the Analysis of Genome-Wide Data from Large Scale Pharmacogenetic Association Studies.Is there an anti-inflammatory effect of statins in rheumatoid arthritis? Analysis of a large routinely collected claims databaseHigh-content drug screening with engineered musculoskeletal tissues50-year trends in US socioeconomic inequalities in health: US-born Black and White Americans, 1959-2008Roles of inflammation, oxidative stress, and vascular dysfunction in hypertension.Statins and neuroprotection: a prescription to move the field forwardAt the crossroads of chemistry and cell biology: inhibiting membrane traffic by small molecules.Cellular trafficking and anticancer activity of Garcinia mangostana extract-encapsulated polymeric nanoparticles.Dietary cholesterol reverses resistance to diet-induced weight gain in mice lacking Niemann-Pick C1-Like 1.Statins and clinical outcome of acute ischemic stroke: a systematic reviewThe clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy.Mapping genes that predict treatment outcome in admixed populationsSimvastatin: a review.Chemoenzymatic synthesis of building blocks for statin side chains.Kinase Substrate Sensor (KISS), a mammalian in situ protein interaction sensor.Discontinued drugs in 2005: cardiovascular drugs.A highly productive, whole-cell DERA chemoenzymatic process for production of key lactonized side-chain intermediates in statin synthesisRole of cholesterol in the development and progression of breast cancerSimvastatin stimulates production of the antiapoptotic protein Bcl-2 via endothelin-1 and NFATc3 in SH-SY5Y cells.Rational improvement of simvastatin synthase solubility in Escherichia coli leads to higher whole-cell biocatalytic activity.Effects of statins on the risk of hepatocellular carcinoma
P2860
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P2860
Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
@ast
Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
@en
Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
@nl
type
label
Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
@ast
Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
@en
Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
@nl
prefLabel
Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
@ast
Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
@en
Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
@nl
P356
P1476
Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors.
@en
P2093
Jonathan A Tobert
P2888
P304
P356
10.1038/NRD1112
P577
2003-07-01T00:00:00Z
P5875
P6179
1044529746