Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
about
K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanismWhy do HIV-1 and HIV-2 use different pathways to develop AZT resistance?Mutations in HIV-1 reverse transcriptase affect the errors made in a single cycle of viral replication.A high-affinity inhibitor of human CD59 enhances complement-mediated virolysis of HIV-1: implications for treatment of HIV-1/AIDSMutation V111I in HIV-2 reverse transcriptase increases the fitness of the nucleoside analogue-resistant K65R and Q151M viruses.The evolution of HIV-1 reverse transcriptase in route to acquisition of Q151M multi-drug resistance is complex and involves mutations in multiple domains.Understanding HIV resistance, fitness, replication capacity and compensation: targeting viral fitness as a therapeutic strategy.Resistance to reverse transcriptase inhibitors used in the treatment and prevention of HIV-1 infection.Increased G-->A transition frequencies displayed by primer grip mutants of human immunodeficiency virus type 1 reverse transcriptaseMechanism of resistance to GS-9148 conferred by the Q151L mutation in HIV-1 reverse transcriptase.Amino acid residues in HIV-2 reverse transcriptase that restrict the development of nucleoside analogue resistance through the excision pathway.
P2860
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P2860
Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
@ast
Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
@en
Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
@nl
type
label
Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
@ast
Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
@en
Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
@nl
prefLabel
Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
@ast
Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
@en
Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
@nl
P2093
P1433
P1476
Pathways for the emergence of multi-dideoxynucleoside-resistant HIV-1 variants.
@en
P2093
Hiroaki Mitsuya
Hsinyi Tsang
Mark F Kavlick
Pope Kosalaraksa
Shigeyoshi Harada
Shintaro Matsumi
P304
P356
10.1097/00002030-200305230-00003
P407
P577
2003-05-01T00:00:00Z