Distinct haematological disorder with deletion of long arm of no. 5 chromosome.
about
The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5qIdentification of RPS14 as a 5q- syndrome gene by RNA interference screenLoss of both CSF1R (FMS) alleles in patients with myelodysplasia and a chromosome 5 deletionCytogenetic features in myelodysplastic syndromesGuarding the 'translation apparatus': defective ribosome biogenesis and the p53 signaling pathwayPP2A: The Achilles Heal in MDS with 5q DeletionDeletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasiaNPM1 deletion is associated with gross chromosomal rearrangements in leukemiaCommon deleted genes in the 5q- syndrome: thrombocytopenia and reduced erythroid colony formation in SPARC null mice.The role of lenalidomide in the management of myelodysplasia with del 5q.Myelodysplastic syndromes: Contemporary review and how we treat.A myeloproliferative disease in two infants associated with eosinophilia and chromosome t(1;5) translocation.A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.WHO-defined 'myelodysplastic syndrome with isolated del(5q)' in 88 consecutive patients: survival data, leukemic transformation rates and prevalence of JAK2, MPL and IDH mutations.Extended survival and reduced risk of AML progression in erythroid-responsive lenalidomide-treated patients with lower-risk del(5q) MDS.Unimpaired terminal erythroid differentiation and preserved enucleation capacity in myelodysplastic 5q(del) clones: a single cell study.The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemiaRibosomopathies: human disorders of ribosome dysfunction.Current therapy of myelodysplastic syndromesCytogenetic analysis in leukemia.Driver somatic mutations identify distinct disease entities within myeloid neoplasms with myelodysplasia.Ribosome defects in disorders of erythropoiesis.Sleeping giants: emerging roles for the fat cadherins in health and disease.The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders.Genetic deletions in AML and MDS.Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders.Clinical utility of lenalidomide in the treatment of myelodysplastic syndromesAnimal models of Diamond Blackfan anemia.Nonrandom chromosomal abnormalities in hematologic disorders of man.How much? How frequent? How long? A clinical guide to new therapies in myelodysplastic syndromesLenalidomide in the context of complex karyotype or interrupted treatment: case reviews of del(5q)MDS patients with unexpected responses.The role of haploinsufficiency of RPS14 and p53 activation in the molecular pathogenesis of the 5q- syndrome.Chromosomal localization of the human c-fms oncogeneLenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients.SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts.Important genes in the pathogenesis of 5q- syndrome and their connection with ribosomal stress and the innate immune system pathway.Molecular pathophysiology of myelodysplastic syndromes.The p53 pathway in hematopoiesis: lessons from mouse models, implications for humans.Practical recommendations on the use of lenalidomide in the management of myelodysplastic syndromes.Chromosome studies in man: past achievements and recent advances
P2860
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P2860
Distinct haematological disorder with deletion of long arm of no. 5 chromosome.
description
1974 nî lūn-bûn
@nan
1974 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1974 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1974年の論文
@ja
1974年論文
@yue
1974年論文
@zh-hant
1974年論文
@zh-hk
1974年論文
@zh-mo
1974年論文
@zh-tw
1974年论文
@wuu
name
Distinct haematological disorder with deletion of long arm of no. 5 chromosome.
@ast
Distinct haematological disorder with deletion of long arm of no. 5 chromosome.
@en
Distinct haematological disorder with deletion of long arm of no. 5 chromosome.
@nl
type
label
Distinct haematological disorder with deletion of long arm of no. 5 chromosome.
@ast
Distinct haematological disorder with deletion of long arm of no. 5 chromosome.
@en
Distinct haematological disorder with deletion of long arm of no. 5 chromosome.
@nl
prefLabel
Distinct haematological disorder with deletion of long arm of no. 5 chromosome.
@ast
Distinct haematological disorder with deletion of long arm of no. 5 chromosome.
@en
Distinct haematological disorder with deletion of long arm of no. 5 chromosome.
@nl
P2093
P356
P1433
P1476
Distinct haematological disorder with deletion of long arm of no. 5 chromosome.
@en
P2093
Cassiman JJ
Michaux JL
Van den Berghe H
P2888
P304
P356
10.1038/251437A0
P407
P577
1974-10-01T00:00:00Z
P6179
1013471585