Clinical pharmacokinetics of imipramine and desipramine.
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The Use of In Vitro Data and Physiologically-Based Pharmacokinetic Modeling to Predict Drug Metabolite Exposure: Desipramine Exposure in Cytochrome P4502D6 Extensive and Poor Metabolizers Following Administration of Imipramine.Absence of effect of stimulants on the phamacokinetics of desipramine in children.Desipramine, substrate for CYP2D6 activity: population pharmacokinetic model and design elements of drug-drug interaction trialsThe role of S-mephenytoin 4'-hydroxylase in imipramine metabolism by human liver microsomes: a two-enzyme kinetic analysis of N-demethylation and 2-hydroxylationCombined norepinephrine/serotonergic reuptake inhibition: effects on maternal behavior, aggression, and oxytocin in the rat.Noradrenergic dysfunction in Alzheimer's disease.Drug bioactivation, covalent binding to target proteins and toxicity relevance.Pharmacological properties of the active metabolites of the antidepressants desipramine and citalopram.Protein binding predictions in infantsPharmacokinetics of antidepressants in patients with hepatic impairment.Comparison of the effects of venlafaxine, desipramine, and paroxetine on noradrenaline- and methoxamine-evoked constriction of the dorsal hand vein.Comparison of the effects of desipramine on noradrenaline- and methoxamine-evoked venoconstriction in man.The effects of desvenlafaxine and paroxetine on the pharmacokinetics of the cytochrome P450 2D6 substrate desipramine in healthy adults.Effect of terbinafine on the pharmacokinetics and pharmacodynamics of desipramine in healthy volunteers identified as cytochrome P450 2D6 (CYP2D6) extensive metabolizers.Development and Qualification of Physiologically Based Pharmacokinetic Models for Drugs With Atypical Distribution Behavior: A Desipramine Case Study.Inhibitory effects of psychotropic drugs on mexiletine metabolism in human liver microsomes: prediction of in vivo drug interactions.The effect of mirabegron, a potent and selective β3-adrenoceptor agonist, on the pharmacokinetics of CYP2D6 substrates desipramine and metoprolol.Exposure to commonly prescribed drugs and the etiology of cryptogenic fibrosing alveolitis: a case-control study.Isozyme selective alterations of the expression of cytochrome P450 during regeneration of male rat liver following partial hepatectomy.
P2860
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P2860
Clinical pharmacokinetics of imipramine and desipramine.
description
1990 nî lūn-bûn
@nan
1990 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Clinical pharmacokinetics of imipramine and desipramine.
@ast
Clinical pharmacokinetics of imipramine and desipramine.
@en
Clinical pharmacokinetics of imipramine and desipramine.
@nl
type
label
Clinical pharmacokinetics of imipramine and desipramine.
@ast
Clinical pharmacokinetics of imipramine and desipramine.
@en
Clinical pharmacokinetics of imipramine and desipramine.
@nl
prefLabel
Clinical pharmacokinetics of imipramine and desipramine.
@ast
Clinical pharmacokinetics of imipramine and desipramine.
@en
Clinical pharmacokinetics of imipramine and desipramine.
@nl
P1476
Clinical pharmacokinetics of imipramine and desipramine.
@en
P2093
P304
P356
10.2165/00003088-199018050-00002
P577
1990-05-01T00:00:00Z
P6179
1048725651