Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.
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Transgenic mice that overexpress mouse apolipoprotein B. Evidence that the DNA sequences controlling intestinal expression of the apolipoprotein B gene are distant from the structural geneIncreased atherosclerosis in hyperlipidemic mice deficient in alpha -tocopherol transfer protein and vitamin EA deficiency of microsomal triglyceride transfer protein reduces apolipoprotein B secretionSusceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B48 or apolipoprotein B100Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" miceMacrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in low density lipoprotein receptor-deficient miceDual mechanisms for the low plasma levels of truncated apolipoprotein B proteins in familial hypobetalipoproteinemia. Analysis of a new mouse model with a nonsense mutation in the Apob geneDefining the atherogenicity of large and small lipoproteins containing apolipoprotein B100Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48Mouse models to study the effect of cardiovascular risk factors on brain structure and cognitionThe effects of second-hand smoke on biological processes important in atherogenesis.ApoE-/- PGC-1α-/- mice display reduced IL-18 levels and do not develop enhanced atherosclerosis.Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD).MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B.Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice.Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivoEstablishment of a transgenic mouse model specifically expressing human serum amyloid A in adipose tissue.Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in mice.Animal models of ischemic stroke. Part one: modeling risk factors.SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesisAdvances in experimental dyslipidemia and atherosclerosis.Lipoprotein size and susceptibility to atherosclerosis--insights from genetically modified mouse modelsTargeted disruption of LDLR causes hypercholesterolemia and atherosclerosis in Yucatan miniature pigsApoB-100-containing lipoproteins are major carriers of 3-iodothyronamine in circulation.The androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female miceMacrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null miceA genetic model for absent chylomicron formation: mice producing apolipoprotein B in the liver, but not in the intestine.Inhibition of atherosclerosis in CD4 T-cell-ablated and nude (nu/nu) C57BL/6 hyperlipidemic miceCultured cells of the blood-brain barrier from apolipoprotein B-100 transgenic mice: effects of oxidized low-density lipoprotein treatment.Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals.Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in miceHigh-resolution association mapping of atherosclerosis loci in miceLow density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: no accentuation by apolipoprotein(a).Progression and disruption of advanced atherosclerotic plaques in murine models.Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein EParadoxical enhancement of atherosclerosis by probucol treatment in apolipoprotein E-deficient mice.Macrophage-specific expression of human lipoprotein lipase accelerates atherosclerosis in transgenic apolipoprotein e knockout mice but not in C57BL/6 mice.Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.Animal models for the atherosclerosis research: a review.Natural killer T cells in atherosclerosis.
P2860
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P2860
Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Transgenic mice expressing hig ...... n response to a high-fat diet.
@ast
Transgenic mice expressing hig ...... n response to a high-fat diet.
@en
Transgenic mice expressing hig ...... n response to a high-fat diet.
@nl
type
label
Transgenic mice expressing hig ...... n response to a high-fat diet.
@ast
Transgenic mice expressing hig ...... n response to a high-fat diet.
@en
Transgenic mice expressing hig ...... n response to a high-fat diet.
@nl
prefLabel
Transgenic mice expressing hig ...... n response to a high-fat diet.
@ast
Transgenic mice expressing hig ...... n response to a high-fat diet.
@en
Transgenic mice expressing hig ...... n response to a high-fat diet.
@nl
P2093
P2860
P356
P1476
Transgenic mice expressing hig ...... in response to a high-fat diet
@en
P2093
D A Purcell-Huynh
D F Johnson
D L Newland
M F Linton
R V Farese
V Pierotti
P2860
P304
P356
10.1172/JCI117915
P407
P577
1995-05-01T00:00:00Z