Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
about
Delineating the biosynthesis of gentamicin x2, the common precursor of the gentamicin C antibiotic complex.HPLC-ELSD determination of kanamycin B in the presence of kanamycin A in fermentation broth.Heterologous production of 4-O-demethylbarbamide, a marine cyanobacterial natural product.C3'-Deoxygenation of Paromamine Catalyzed by a Radical S-Adenosylmethionine Enzyme: Characterization of the Enzyme AprD4 and Its Reductase Partner AprD3.Synthetic biological approaches to natural product biosynthesis.2-Deoxystreptamine-containing aminoglycoside antibiotics: recent advances in the characterization and manipulation of their biosynthetic pathways.Achievements and impacts of glycosylation reactions involved in natural product biosynthesis in prokaryotes.Developing Streptomyces venezuelae as a cell factory for the production of small molecules used in drug discovery.Aminoglycoside Antibiotics: New Insights into the Biosynthetic Machinery of Old Drugs.Parallel pathways in the biosynthesis of aminoglycoside antibiotics.Genetic regulation and manipulation for natural product discovery.Modulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus via metabolic engineering.Specificity and promiscuity at the branch point in gentamicin biosynthesis.The last step of kanamycin biosynthesis: unique deamination reaction catalyzed by the α-ketoglutarate-dependent nonheme iron dioxygenase KanJ and the NADPH-dependent reductase KanK.Re-engineering of genetic circuit for 2-deoxystreptamine (2-DOS) biosynthesis in Escherichia coli BL21 (DE3).Characterization and engineering of the ethylmalonyl-CoA pathway towards the improved heterologous production of polyketides in Streptomyces venezuelae.Chiral phosphoric acid-catalyzed desymmetrizative glycosylation of 2-deoxystreptamine and its application to aminoglycoside synthesis.Streptomyces venezuelae TX-TL - a next generation cell-free synthetic biology tool.Istamycin aminoglycosides profiling and their characterization in Streptomyces tenjimariensis ATCC 31603 culture using high-performance liquid chromatography with tandem mass spectrometry.Characterization of fortimicin aminoglycoside profiles produced from Micromonospora olivasterospora DSM 43868 by high-performance liquid chromatography-electrospray ionization-ion trap-mass spectrometry.Photoelectrochemical aptasensor for the sensitive and selective detection of kanamycin based on Au nanoparticle functionalized self-doped TiO2 nanotube arrays.Regio-selectively reduced streptogramin A analogue, 5,6-dihydrovirginiamycin M1 exhibits improved potency against MRSA.Genetic engineering combined with random mutagenesis to enhance G418 production in Micromonospora echinospora.Synthetic Biology of Antibiotic Production
P2860
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P2860
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
@ast
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
@en
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
@nl
type
label
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
@ast
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
@en
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
@nl
prefLabel
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
@ast
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
@en
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
@nl
P2093
P2860
P921
P356
P1476
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
@en
P2093
Ah Reum Han
Eui Min Kim
Eun Ji Kim
Jae Kyung Sohng
Je Won Park
Keshav Kumar Nepal
Sung Ryeol Park
Yeo Joon Yoon
Yeon Hee Ban
P2860
P2888
P304
P356
10.1038/NCHEMBIO.671
P577
2011-10-09T00:00:00Z
P5875
P6179
1015272495