Modeling, molecular dynamics simulation, and mutation validation for structure of cannabinoid receptor 2 based on known crystal structures of GPCRs.
about
Exploring the mechanism of F282L mutation-caused constitutive activity of GPCR by a computational study.Difference and Influence of Inactive and Active States of Cannabinoid Receptor Subtype CB2: From Conformation to Drug Discovery.Allosteric Binding Site and Activation Mechanism of Class C G-Protein Coupled Receptors: Metabotropic Glutamate Receptor Family.Design and activity of AP endonuclease-1 inhibitors.Structural insight into tetrameric hTRPV1 from homology modeling, molecular docking, molecular dynamics simulation, virtual screening, and bioassay validations.Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion.Computational Advances for the Development of Allosteric Modulators and Bitopic Ligands in G Protein-Coupled ReceptorsMetal binding mediated conformational change of XPA protein:a potential cytotoxic mechanism of nickel in the nucleotide excision repairMulti-Functional Diarylurea Small Molecule Inhibitors of TRPV1 with Therapeutic Potential for Neuroinflammation.Heat-shock protein 90 (Hsp90) as anticancer target for drug discovery: an ample computational perspective.Targeting cannabinoid receptor-2 pathway by phenylacetylamide suppresses the proliferation of human myeloma cells through mitotic dysregulation and cytoskeleton disruption.StemCellCKB: An Integrated Stem Cell-Specific Chemogenomics KnowledgeBase for Target Identification and Systems-Pharmacology Research.The endocannabinoid system in the baboon (Papio spp.) as a complex framework for developmental pharmacology.Unraveling the conformational determinants of LARP7 and 7SK small nuclear RNA by theoretical approaches.Binding mechanisms of 1,4-dihydropyridine derivatives to L-type calcium channel Cav1.2: a molecular modeling study.Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage.Chemogenomics knowledgebase and systems pharmacology for hallucinogen target identification-Salvinorin A as a case study.Allosteric Modulation of Intact γ-Secretase Structural Dynamics.Selective cannabinoid 2 receptor stimulation reduces tubular epithelial cell damage following renal ischemia-reperfusion injury.Insight into the key features for ligand binding in Y1230 mutated c-Met kinase domain by molecular dynamics simulations.The cyclohexene derivative MC-3129 exhibits antileukemic activity via RhoA/ROCK1/PTEN/PI3K/Akt pathway-mediated mitochondrial translocation of cofilin.
P2860
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P2860
Modeling, molecular dynamics simulation, and mutation validation for structure of cannabinoid receptor 2 based on known crystal structures of GPCRs.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Modeling, molecular dynamics s ...... n crystal structures of GPCRs.
@ast
Modeling, molecular dynamics s ...... n crystal structures of GPCRs.
@en
Modeling, molecular dynamics s ...... n crystal structures of GPCRs.
@nl
type
label
Modeling, molecular dynamics s ...... n crystal structures of GPCRs.
@ast
Modeling, molecular dynamics s ...... n crystal structures of GPCRs.
@en
Modeling, molecular dynamics s ...... n crystal structures of GPCRs.
@nl
prefLabel
Modeling, molecular dynamics s ...... n crystal structures of GPCRs.
@ast
Modeling, molecular dynamics s ...... n crystal structures of GPCRs.
@en
Modeling, molecular dynamics s ...... n crystal structures of GPCRs.
@nl
P2093
P2860
P921
P356
P1476
Modeling, molecular dynamics s ...... wn crystal structures of GPCRs
@en
P2093
Ananda Chowdhury
Lirong Wang
Mohammed Hamed Alqarni
Xiang-Qun Xie
Zhiwei Feng
P2860
P304
P356
10.1021/CI5002718
P50
P577
2014-09-05T00:00:00Z