Chloroquine inhibits the intracellular multiplication of Legionella pneumophila by limiting the availability of iron. A potential new mechanism for the therapeutic effect of chloroquine against intracellular pathogens
about
Antimalarial therapy selection for quinolone resistance among Escherichia coli in the absence of quinolone exposure, in tropical South AmericaQuinine sulfate and bacterial invasionCryptococcus neoformans resides in an acidic phagolysosome of human macrophagesChloroquine induces human mononuclear phagocytes to inhibit and kill Cryptococcus neoformans by a mechanism independent of iron deprivationEnhanced resistance to Cryptococcus neoformans infection induced by chloroquine in a murine model of meningoencephalitisThe major iron-containing protein of Legionella pneumophila is an aconitase homologous with the human iron-responsive element-binding proteinDevelopment of clinical methods of iron deprivation for suppression of neoplastic and infectious diseases.Regulation of transferrin receptor expression and ferritin content in human mononuclear phagocytes. Coordinate upregulation by iron transferrin and downregulation by interferon gamma.Inhibition of intramacrophage growth of Penicillium marneffei by 4-aminoquinolines.The Legionella pneumophila iraAB locus is required for iron assimilation, intracellular infection, and virulence.Effects of Anaplasma phagocytophilum on host cell ferritin mRNA and protein levels.Relationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae.Legionella pneumophila feoAB promotes ferrous iron uptake and intracellular infection.Chloroquine induces human macrophage killing of Histoplasma capsulatum by limiting the availability of intracellular iron and is therapeutic in a murine model of histoplasmosisAbrogation of gamma interferon-induced inhibition of Ehrlichia chaffeensis infection in human monocytes with iron-transferrin.Inhibition of growth of Histoplasma capsulatum yeast cells in human macrophages by the iron chelator VUF 8514 and comparison of VUF 8514 with deferoxamine.Growth of Francisella tularensis LVS in macrophages: the acidic intracellular compartment provides essential iron required for growthIdentification of TonB homologs in the family Enterobacteriaceae and evidence for conservation of TonB-dependent energy transduction complexesSuperinfection in malaria: Plasmodium shows its iron will.Strategies of Intracellular Pathogens for Obtaining Iron from the EnvironmentRole of Toll-like receptor 9 in Legionella pneumophila-induced interleukin-12 p40 production in bone marrow-derived dendritic cells and macrophages from permissive and nonpermissive mice.Legionella pneumophila replication vacuoles mature into acidic, endocytic organellesKilling of Escherichia coli by Crohn's Disease Monocyte-derived Macrophages and Its Enhancement by Hydroxychloroquine and Vitamin DIron in innate immunity: starve the invaders.Francisella tularensis phagosomal escape does not require acidification of the phagosome.Tumor necrosis factor alpha (TNFalpha) promotes growth of virulent Mycobacterium tuberculosis in human monocytes iron-mediated growth suppression is correlated with decreased release of TNFalpha from iron-treated infected monocytes.Quantitative assessment of cytosolic Salmonella in epithelial cells.Efficacy of Resistance to Francisella Imparted by ITY/NRAMP/SLC11A1 Depends on Route of Infection.Gamma interferon-activated human macrophages and Toxoplasma gondii, Chlamydia psittaci, and Leishmania donovani: antimicrobial role of limiting intracellular iron.Xenophagy in Helicobacter pylori- and Epstein-Barr virus-induced gastric cancer.Differential modulation of intracellular survival of cytosolic and vacuolar pathogens by curcumin.The CovS/CovR acid response regulator is required for intracellular survival of group B Streptococcus in macrophages.Bafilomycin A1 and intracellular multiplication of Legionella pneumophila.Chloroquine stimulates nitric oxide synthesis in murine, porcine, and human endothelial cells.Enhanced anticryptococcal activity of chloroquine in phosphatidylserine-containing liposomes in a murine model.Fungistatic effect of hydroxychloroquine, lessons from a case.In vitro Synergism between Chloroquine and Antibiotics against Orientia tsutsugamushi.Assessment of chloroquine as a modulator of immune activation to improve CD4 recovery in immune nonresponding HIV-infected patients receiving antiretroviral therapy.Chloroquine inhibits Paracoccidioides brasiliensis survival within human monocytes by limiting the availability of intracellular iron.Monitoring lactoferrin iron levels by fluorescence resonance energy transfer: a combined chemical and computational study.
P2860
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P2860
Chloroquine inhibits the intracellular multiplication of Legionella pneumophila by limiting the availability of iron. A potential new mechanism for the therapeutic effect of chloroquine against intracellular pathogens
description
1991 nî lūn-bûn
@nan
1991 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Chloroquine inhibits the intra ...... gainst intracellular pathogens
@ast
Chloroquine inhibits the intra ...... gainst intracellular pathogens
@en
Chloroquine inhibits the intra ...... gainst intracellular pathogens
@nl
type
label
Chloroquine inhibits the intra ...... gainst intracellular pathogens
@ast
Chloroquine inhibits the intra ...... gainst intracellular pathogens
@en
Chloroquine inhibits the intra ...... gainst intracellular pathogens
@nl
prefLabel
Chloroquine inhibits the intra ...... gainst intracellular pathogens
@ast
Chloroquine inhibits the intra ...... gainst intracellular pathogens
@en
Chloroquine inhibits the intra ...... gainst intracellular pathogens
@nl
P2860
P356
P1476
Chloroquine inhibits the intra ...... gainst intracellular pathogens
@en
P2093
P2860
P304
P356
10.1172/JCI115301
P407
P577
1991-07-01T00:00:00Z