Rational design and synthesis of optimized glycoclusters for multivalent lectin-carbohydrate interactions: influence of the linker arm.
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Aromatic thioglycoside inhibitors against the virulence factor LecA from Pseudomonas aeruginosaStructure-based optimization of the terminal tripeptide in glycopeptide dendrimer inhibitors of Pseudomonas aeruginosa biofilms targeting LecAA LecA ligand identified from a galactoside-conjugate array inhibits host cell invasion by Pseudomonas aeruginosaFucofullerenes as tight ligands of RSL and LecB, two bacterial lectins.Glycopeptide dendrimers as Pseudomonas aeruginosa biofilm inhibitors.The influence of the aromatic aglycon of galactoclusters on the binding of LecA: a case study with O-phenyl, S-phenyl, O-benzyl, S-benzyl, O-biphenyl and O-naphthyl aglycons.Multivalent glycoconjugates as anti-pathogenic agentsGlycomaterials for probing host-pathogen interactions and the immune response.Multivalent glycocalixarenes for recognition of biological macromolecules: glycocalyx mimics capable of multitasking.Multivalent glycoconjugate syntheses and applications using aromatic scaffolds.Bridging lectin binding sites by multivalent carbohydrates.Design and Synthesis of Galactosylated Bifurcated Ligands with Nanomolar Affinity for Lectin LecA from Pseudomonas aeruginosa.Toward the Rational Design of Galactosylated Glycoclusters That Target Pseudomonas aeruginosa Lectin A (LecA): Influence of Linker Arms That Lead to Low-Nanomolar Multivalent Ligands.Importance of topology for glycocluster binding to Pseudomonas aeruginosa and Burkholderia ambifaria bacterial lectins.Adaptable synthesis of C-lactosyl glycoclusters and their binding properties with galectin-3.Glyconanosynthons as powerful scaffolds and building blocks for the rapid construction of multifaceted, dense and chiral dendrimers.Synthesis of multivalent carbohydrate-centered glycoclusters as nanomolar ligands of the bacterial lectin LecA from Pseudomonas aeruginosa.Synthesis of a selective inhibitor of a fucose binding bacterial lectin from Burkholderia ambifaria.Pseudomonas Aeruginosa Lectins As Targets for Novel Antibacterials.Glycosylated Porphyrins, Phthalocyanines, and Other Porphyrinoids for Diagnostics and Therapeutics.Applications of isothermal titration calorimetry - the research and technical developments from 2011 to 2015.Inhibitory Effect of Multivalent Rhamnobiosides on Recombinant Horseshoe Crab Plasma Lectin Interactions with Pseudomonas aeruginosa PAO1.Biologically Active Heteroglycoclusters Constructed on a Pillar[5]arene-Containing [2]Rotaxane Scaffold.Effects of the Surface Densities of Glycoclusters on the Determination of Their IC50 and Kd Value Determination by Using a Microarray.Development and optimization of a competitive binding assay for the galactophilic low affinity lectin LecA from Pseudomonas aeruginosa.Pentavalent pillar[5]arene-based glycoclusters and their multivalent binding to pathogenic bacterial lectins.Thiourea-based spacers in potent divalent inhibitors of Pseudomonas aeruginosa virulence lectin LecA.Functionalization of a Rigid Divalent Ligand for LecA, a Bacterial Adhesion Lectin.Tetravalent glycocyclopeptide with nanomolar affinity to wheat germ agglutinin.Perylenediimide-based glycoclusters as high affinity ligands of bacterial lectins: synthesis, binding studies and anti-adhesive properties.Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging.What regulates the catalytic activities in AGE catalysis? An answer from quantum mechanics/molecular mechanics simulations.Mannose-centered aromatic galactoclusters inhibit the biofilm formation of Pseudomonas aeruginosa.A highly versatile convergent/divergent "onion peel" synthetic strategy toward potent multivalent glycodendrimers.Mechanistic Insight into Nanomolar Binding of Multivalent Neoglycopeptides to Wheat Germ Agglutinin.Optimizing divalent inhibitors of Pseudomonas aeruginosa lectin LecA by using a rigid spacer.Hetero-Multivalency of Pseudomonas aeruginosa Lectin LecA Binding to Model Membranes.Synthesis of Galactoclusters by Metal-Free Thiol “Click Chemistry” and Their Binding Affinities forPseudomonas aeruginosaLectin LecASynthesis of branched-phosphodiester and mannose-centered fucosylated glycoclusters and their binding studies with Burkholderia ambifaria lectin (BambL)Glycomics@ExPASy: Bridging the gap
P2860
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P2860
Rational design and synthesis of optimized glycoclusters for multivalent lectin-carbohydrate interactions: influence of the linker arm.
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Rational design and synthesis ...... : influence of the linker arm.
@ast
Rational design and synthesis ...... : influence of the linker arm.
@en
Rational design and synthesis ...... : influence of the linker arm.
@nl
type
label
Rational design and synthesis ...... : influence of the linker arm.
@ast
Rational design and synthesis ...... : influence of the linker arm.
@en
Rational design and synthesis ...... : influence of the linker arm.
@nl
prefLabel
Rational design and synthesis ...... : influence of the linker arm.
@ast
Rational design and synthesis ...... : influence of the linker arm.
@en
Rational design and synthesis ...... : influence of the linker arm.
@nl
P2093
P2860
P50
P356
P1476
Rational design and synthesis ...... : influence of the linker arm.
@en
P2093
Jean-Pierre Praly
Samy Cecioni
Sébastien Vidal
P2860
P304
P356
10.1002/CHEM.201200010
P407
P577
2012-04-04T00:00:00Z